BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

128 related articles for article (PubMed ID: 18295447)

  • 1. Transcriptional repression of c-Jun's E3 ubiquitin ligases contributes to c-Jun induction by UV.
    Anzi S; Finkin S; Shaulian E
    Cell Signal; 2008 May; 20(5):862-71. PubMed ID: 18295447
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The ubiquitin ligase SCFFbw7 antagonizes apoptotic JNK signaling.
    Nateri AS; Riera-Sans L; Da Costa C; Behrens A
    Science; 2004 Feb; 303(5662):1374-8. PubMed ID: 14739463
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The v-Jun point mutation allows c-Jun to escape GSK3-dependent recognition and destruction by the Fbw7 ubiquitin ligase.
    Wei W; Jin J; Schlisio S; Harper JW; Kaelin WG
    Cancer Cell; 2005 Jul; 8(1):25-33. PubMed ID: 16023596
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Fbw7 promotes ubiquitin-dependent degradation of c-Myb: involvement of GSK3-mediated phosphorylation of Thr-572 in mouse c-Myb.
    Kitagawa K; Hiramatsu Y; Uchida C; Isobe T; Hattori T; Oda T; Shibata K; Nakamura S; Kikuchi A; Kitagawa M
    Oncogene; 2009 Jun; 28(25):2393-405. PubMed ID: 19421138
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Regulation of the tumour suppressor Fbw7α by PKC-dependent phosphorylation and cancer-associated mutations.
    Durgan J; Parker PJ
    Biochem J; 2010 Nov; 432(1):77-87. PubMed ID: 20815813
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The F-box protein Fbw7 is required for cerebellar development.
    Jandke A; Da Costa C; Sancho R; Nye E; Spencer-Dene B; Behrens A
    Dev Biol; 2011 Oct; 358(1):201-12. PubMed ID: 21827743
    [TBL] [Abstract][Full Text] [Related]  

  • 7. F-box and WD repeat domain-containing 7 regulates intestinal cell lineage commitment and is a haploinsufficient tumor suppressor.
    Sancho R; Jandke A; Davis H; Diefenbacher ME; Tomlinson I; Behrens A
    Gastroenterology; 2010 Sep; 139(3):929-41. PubMed ID: 20638938
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A nucleolar isoform of the Fbw7 ubiquitin ligase regulates c-Myc and cell size.
    Welcker M; Orian A; Grim JE; Eisenman RN; Clurman BE
    Curr Biol; 2004 Oct; 14(20):1852-7. PubMed ID: 15498494
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Retinoic acid inhibits induction of c-Jun protein by ultraviolet radiation that occurs subsequent to activation of mitogen-activated protein kinase pathways in human skin in vivo.
    Fisher GJ; Talwar HS; Lin J; Lin P; McPhillips F; Wang Z; Li X; Wan Y; Kang S; Voorhees JJ
    J Clin Invest; 1998 Mar; 101(6):1432-40. PubMed ID: 9502786
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Tumor suppressor activities of the Fbw7 E3 ubiquitin ligase receptor.
    Fuchs SY
    Cancer Biol Ther; 2005 May; 4(5):506-8. PubMed ID: 15908780
    [TBL] [Abstract][Full Text] [Related]  

  • 11. E3 Ubiquitin Ligase Fbw7 Negatively Regulates Osteoblast Differentiation by Targeting Runx2 for Degradation.
    Kumar Y; Kapoor I; Khan K; Thacker G; Khan MP; Shukla N; Kanaujiya JK; Sanyal S; Chattopadhyay N; Trivedi AK
    J Biol Chem; 2015 Dec; 290(52):30975-87. PubMed ID: 26542806
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Ubiquitin-mediated fluorescence complementation reveals that Jun ubiquitinated by Itch/AIP4 is localized to lysosomes.
    Fang D; Kerppola TK
    Proc Natl Acad Sci U S A; 2004 Oct; 101(41):14782-7. PubMed ID: 15469925
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Fbw7 and Usp28 regulate myc protein stability in response to DNA damage.
    Popov N; Herold S; Llamazares M; Schülein C; Eilers M
    Cell Cycle; 2007 Oct; 6(19):2327-31. PubMed ID: 17873522
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Prognostic significance of Fbw7 in human melanoma and its role in cell migration.
    Cheng Y; Chen G; Martinka M; Ho V; Li G
    J Invest Dermatol; 2013 Jul; 133(7):1794-802. PubMed ID: 23381582
    [TBL] [Abstract][Full Text] [Related]  

  • 15. AP-1 regulates cyclin D1 and c-MYC transcription in an AKT-dependent manner in response to mTOR inhibition: role of AIP4/Itch-mediated JUNB degradation.
    Vartanian R; Masri J; Martin J; Cloninger C; Holmes B; Artinian N; Funk A; Ruegg T; Gera J
    Mol Cancer Res; 2011 Jan; 9(1):115-30. PubMed ID: 21135252
    [TBL] [Abstract][Full Text] [Related]  

  • 16. SAG/ROC2/Rbx2 is a novel activator protein-1 target that promotes c-Jun degradation and inhibits 12-O-tetradecanoylphorbol-13-acetate-induced neoplastic transformation.
    Gu Q; Tan M; Sun Y
    Cancer Res; 2007 Apr; 67(8):3616-25. PubMed ID: 17440073
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Role of the ubiquitin ligase Fbw7 in cancer progression.
    Cheng Y; Li G
    Cancer Metastasis Rev; 2012 Jun; 31(1-2):75-87. PubMed ID: 22124735
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Rack1 protects N-terminal phosphorylated c-Jun from Fbw7-mediated degradation.
    Zhang J; Zhu F; Li X; Dong Z; Xu Y; Peng C; Li S; Cho YY; Yao K; Zykova TA; Bode AM; Dong Z
    Oncogene; 2012 Apr; 31(14):1835-44. PubMed ID: 21860413
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Fbw7 repression by hes5 creates a feedback loop that modulates Notch-mediated intestinal and neural stem cell fate decisions.
    Sancho R; Blake SM; Tendeng C; Clurman BE; Lewis J; Behrens A
    PLoS Biol; 2013; 11(6):e1001586. PubMed ID: 23776410
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Phosphorylation-dependent degradation of c-Myc is mediated by the F-box protein Fbw7.
    Yada M; Hatakeyama S; Kamura T; Nishiyama M; Tsunematsu R; Imaki H; Ishida N; Okumura F; Nakayama K; Nakayama KI
    EMBO J; 2004 May; 23(10):2116-25. PubMed ID: 15103331
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.