155 related articles for article (PubMed ID: 18295795)
1. Alpha-RgIA, a novel conotoxin that blocks the alpha9alpha10 nAChR: structure and identification of key receptor-binding residues.
Ellison M; Feng ZP; Park AJ; Zhang X; Olivera BM; McIntosh JM; Norton RS
J Mol Biol; 2008 Apr; 377(4):1216-27. PubMed ID: 18295795
[TBL] [Abstract][Full Text] [Related]
2. Critical residue properties for potency and selectivity of α-Conotoxin RgIA towards α9α10 nicotinic acetylcholine receptors.
Huynh PN; Harvey PJ; Gajewiak J; Craik DJ; Michael McIntosh J
Biochem Pharmacol; 2020 Nov; 181():114124. PubMed ID: 32593612
[TBL] [Abstract][Full Text] [Related]
3. Rational design of alpha-conotoxin analogues targeting alpha7 nicotinic acetylcholine receptors: improved antagonistic activity by incorporation of proline derivatives.
Armishaw C; Jensen AA; Balle T; Clark RJ; Harpsøe K; Skonberg C; Liljefors T; Strømgaard K
J Biol Chem; 2009 Apr; 284(14):9498-512. PubMed ID: 19131337
[TBL] [Abstract][Full Text] [Related]
4. αO-Conotoxin GeXIVA disulfide bond isomers exhibit differential sensitivity for various nicotinic acetylcholine receptors but retain potency and selectivity for the human α9α10 subtype.
Zhangsun D; Zhu X; Kaas Q; Wu Y; Craik DJ; McIntosh JM; Luo S
Neuropharmacology; 2017 Dec; 127():243-252. PubMed ID: 28416445
[TBL] [Abstract][Full Text] [Related]
5. Selective Penicillamine Substitution Enables Development of a Potent Analgesic Peptide that Acts through a Non-Opioid-Based Mechanism.
Gajewiak J; Christensen SB; Dowell C; Hararah F; Fisher F; Huynh PN; Olivera BM; McIntosh JM
J Med Chem; 2021 Jul; 64(13):9271-9278. PubMed ID: 34142837
[TBL] [Abstract][Full Text] [Related]
6. Structural determinants of selective alpha-conotoxin binding to a nicotinic acetylcholine receptor homolog AChBP.
Ulens C; Hogg RC; Celie PH; Bertrand D; Tsetlin V; Smit AB; Sixma TK
Proc Natl Acad Sci U S A; 2006 Mar; 103(10):3615-20. PubMed ID: 16505382
[TBL] [Abstract][Full Text] [Related]
7. On-resin strategy to label α-conotoxins: Cy5-RgIA, a potent α9α10 nicotinic acetylcholine receptor imaging probe.
Muttenthaler M; Nevin ST; Inserra M; Lewis RJ; Adams DJ; Alewood P
Aust J Chem; 2020; 73(4):327-333. PubMed ID: 32394983
[TBL] [Abstract][Full Text] [Related]
8. Potency- and Selectivity-Enhancing Mutations of Conotoxins for Nicotinic Acetylcholine Receptors Can Be Predicted Using Accurate Free-Energy Calculations.
Katz D; DiMattia MA; Sindhikara D; Li H; Abraham N; Leffler AE
Mar Drugs; 2021 Jun; 19(7):. PubMed ID: 34202022
[TBL] [Abstract][Full Text] [Related]
9. A new alpha-conotoxin which targets alpha3beta2 nicotinic acetylcholine receptors.
Cartier GE; Yoshikami D; Gray WR; Luo S; Olivera BM; McIntosh JM
J Biol Chem; 1996 Mar; 271(13):7522-8. PubMed ID: 8631783
[TBL] [Abstract][Full Text] [Related]
10. Ribbon α-Conotoxin KTM Exhibits Potent Inhibition of Nicotinic Acetylcholine Receptors.
Marquart LA; Turner MW; Warner LR; King MD; Groome JR; McDougal OM
Mar Drugs; 2019 Nov; 17(12):. PubMed ID: 31795126
[TBL] [Abstract][Full Text] [Related]
11. α-Conotoxins Enhance both the In Vivo Suppression of Ehrlich carcinoma Growth and In Vitro Reduction in Cell Viability Elicited by Cyclooxygenase and Lipoxygenase Inhibitors.
Osipov AV; Terpinskaya TI; Yanchanka T; Balashevich T; Zhmak MN; Tsetlin VI; Utkin YN
Mar Drugs; 2020 Apr; 18(4):. PubMed ID: 32272633
[TBL] [Abstract][Full Text] [Related]
12. Dual Antagonism of α9α10 nAChR and GABA
Li X; Tae HS; Chen S; Yousuf A; Huang L; Zhang J; Jiang T; Adams DJ; Yu R
J Med Chem; 2024 Jan; 67(2):971-987. PubMed ID: 38217860
[TBL] [Abstract][Full Text] [Related]
13. Alpha9 nicotinic acetylcholine receptors and the treatment of pain.
McIntosh JM; Absalom N; Chebib M; Elgoyhen AB; Vincler M
Biochem Pharmacol; 2009 Oct; 78(7):693-702. PubMed ID: 19477168
[TBL] [Abstract][Full Text] [Related]
14. Computational Design of α-Conotoxins to Target Specific Nicotinic Acetylcholine Receptor Subtypes.
Wu X; Hone AJ; Huang YH; Clark RJ; McIntosh JM; Kaas Q; Craik DJ
Chemistry; 2024 Feb; 30(7):e202302909. PubMed ID: 37910861
[TBL] [Abstract][Full Text] [Related]
15. Discovery of peptide ligands through docking and virtual screening at nicotinic acetylcholine receptor homology models.
Leffler AE; Kuryatov A; Zebroski HA; Powell SR; Filipenko P; Hussein AK; Gorson J; Heizmann A; Lyskov S; Tsien RW; Poget SF; Nicke A; Lindstrom J; Rudy B; Bonneau R; Holford M
Proc Natl Acad Sci U S A; 2017 Sep; 114(38):E8100-E8109. PubMed ID: 28874590
[TBL] [Abstract][Full Text] [Related]
16. Synthetic α-conotoxin mutants as probes for studying nicotinic acetylcholine receptors and in the development of novel drug leads.
Armishaw CJ
Toxins (Basel); 2010 Jun; 2(6):1471-99. PubMed ID: 22069647
[TBL] [Abstract][Full Text] [Related]
17. Rational Design of Potent α-Conotoxin PeIA Analogues with Non-Natural Amino Acids for the Inhibition of Human α9α10 Nicotinic Acetylcholine Receptors.
Li T; Tae HS; Liang J; Zhang Z; Li X; Jiang T; Adams DJ; Yu R
Mar Drugs; 2024 Feb; 22(3):. PubMed ID: 38535451
[TBL] [Abstract][Full Text] [Related]
18. Basic Residues at Position 11 of α-Conotoxin LvIA Influence Subtype Selectivity between α3β2 and α3β4 Nicotinic Receptors via an Electrostatic Mechanism.
Haufe Y; Kuruva V; Samanani Z; Lokaj G; Kamnesky G; Shadamarshan P; Shahoei R; Katz D; Sampson JM; Pusch M; Brik A; Nicke A; Leffler AE
ACS Chem Neurosci; 2023 Dec; 14(24):4311-4322. PubMed ID: 38051211
[TBL] [Abstract][Full Text] [Related]
19. Aspartic acid mutagenesis of αO-Conotoxin GeXIVA isomers reveals arginine residues crucial for inhibition of the α9α10 nicotinic acetylcholine receptor.
Luo A; He J; Yu J; Wu Y; Harvey PJ; Kasheverov IE; Kudryavtsev DS; McIntosh JM; Tsetlin VI; Craik DJ; Zhangsun D; Luo S
Int J Biol Macromol; 2024 May; 271(Pt 1):132472. PubMed ID: 38772455
[TBL] [Abstract][Full Text] [Related]
20. Peptides from the Sea Anemone
Kasheverov IE; Logashina YA; Kornilov FD; Lushpa VA; Maleeva EE; Korolkova YV; Yu J; Zhu X; Zhangsun D; Luo S; Stensvåg K; Kudryavtsev DS; Mineev KS; Andreev YA
Toxins (Basel); 2022 Dec; 15(1):. PubMed ID: 36668848
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
