BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

272 related articles for article (PubMed ID: 18298651)

  • 1. Proteasome inhibitor-induced apoptosis is mediated by positive feedback amplification of PKCdelta proteolytic activation and mitochondrial translocation.
    Sun F; Kanthasamy A; Song C; Yang Y; Anantharam V; Kanthasamy AG
    J Cell Mol Med; 2008 Dec; 12(6A):2467-81. PubMed ID: 18298651
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Vanadium induces dopaminergic neurotoxicity via protein kinase Cdelta dependent oxidative signaling mechanisms: relevance to etiopathogenesis of Parkinson's disease.
    Afeseh Ngwa H; Kanthasamy A; Anantharam V; Song C; Witte T; Houk R; Kanthasamy AG
    Toxicol Appl Pharmacol; 2009 Oct; 240(2):273-85. PubMed ID: 19646462
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Dieldrin induces apoptosis by promoting caspase-3-dependent proteolytic cleavage of protein kinase Cdelta in dopaminergic cells: relevance to oxidative stress and dopaminergic degeneration.
    Kitazawa M; Anantharam V; Kanthasamy AG
    Neuroscience; 2003; 119(4):945-64. PubMed ID: 12831855
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Dopaminergic neurotoxicant 6-OHDA induces oxidative damage through proteolytic activation of PKCδ in cell culture and animal models of Parkinson's disease.
    Latchoumycandane C; Anantharam V; Jin H; Kanthasamy A; Kanthasamy A
    Toxicol Appl Pharmacol; 2011 Nov; 256(3):314-23. PubMed ID: 21846476
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Protein kinase Cdelta is a key downstream mediator of manganese-induced apoptosis in dopaminergic neuronal cells.
    Latchoumycandane C; Anantharam V; Kitazawa M; Yang Y; Kanthasamy A; Kanthasamy AG
    J Pharmacol Exp Ther; 2005 Apr; 313(1):46-55. PubMed ID: 15608081
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Blockade of PKCdelta proteolytic activation by loss of function mutants rescues mesencephalic dopaminergic neurons from methylcyclopentadienyl manganese tricarbonyl (MMT)-induced apoptotic cell death.
    Anantharam V; Kitazawa M; Latchoumycandane C; Kanthasamy A; Kanthasamy AG
    Ann N Y Acad Sci; 2004 Dec; 1035():271-89. PubMed ID: 15681813
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Methamphetamine-induced neurotoxicity linked to ubiquitin-proteasome system dysfunction and autophagy-related changes that can be modulated by protein kinase C delta in dopaminergic neuronal cells.
    Lin M; Chandramani-Shivalingappa P; Jin H; Ghosh A; Anantharam V; Ali S; Kanthasamy AG; Kanthasamy A
    Neuroscience; 2012 May; 210():308-32. PubMed ID: 22445524
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Environmental neurotoxin dieldrin induces apoptosis via caspase-3-dependent proteolytic activation of protein kinase C delta (PKCdelta): Implications for neurodegeneration in Parkinson's disease.
    Kanthasamy AG; Kitazawa M; Yang Y; Anantharam V; Kanthasamy A
    Mol Brain; 2008 Oct; 1():12. PubMed ID: 18945348
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Caspase-3-dependent proteolytic cleavage of protein kinase Cdelta is essential for oxidative stress-mediated dopaminergic cell death after exposure to methylcyclopentadienyl manganese tricarbonyl.
    Anantharam V; Kitazawa M; Wagner J; Kaul S; Kanthasamy AG
    J Neurosci; 2002 Mar; 22(5):1738-51. PubMed ID: 11880503
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A novel peptide inhibitor targeted to caspase-3 cleavage site of a proapoptotic kinase protein kinase C delta (PKCdelta) protects against dopaminergic neuronal degeneration in Parkinson's disease models.
    Kanthasamy AG; Anantharam V; Zhang D; Latchoumycandane C; Jin H; Kaul S; Kanthasamy A
    Free Radic Biol Med; 2006 Nov; 41(10):1578-89. PubMed ID: 17045926
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Caspase-3 dependent proteolytic activation of protein kinase C delta mediates and regulates 1-methyl-4-phenylpyridinium (MPP+)-induced apoptotic cell death in dopaminergic cells: relevance to oxidative stress in dopaminergic degeneration.
    Kaul S; Kanthasamy A; Kitazawa M; Anantharam V; Kanthasamy AG
    Eur J Neurosci; 2003 Sep; 18(6):1387-401. PubMed ID: 14511319
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Environmental neurotoxic pesticide dieldrin activates a non receptor tyrosine kinase to promote PKCδ-mediated dopaminergic apoptosis in a dopaminergic neuronal cell model.
    Saminathan H; Asaithambi A; Anantharam V; Kanthasamy AG; Kanthasamy A
    Neurotoxicology; 2011 Oct; 32(5):567-77. PubMed ID: 21801747
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Suppression of caspase-3-dependent proteolytic activation of protein kinase C delta by small interfering RNA prevents MPP+-induced dopaminergic degeneration.
    Yang Y; Kaul S; Zhang D; Anantharam V; Kanthasamy AG
    Mol Cell Neurosci; 2004 Mar; 25(3):406-21. PubMed ID: 15033169
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Activation of protein kinase C delta by proteolytic cleavage contributes to manganese-induced apoptosis in dopaminergic cells: protective role of Bcl-2.
    Kitazawa M; Anantharam V; Yang Y; Hirata Y; Kanthasamy A; Kanthasamy AG
    Biochem Pharmacol; 2005 Jan; 69(1):133-46. PubMed ID: 15588722
    [TBL] [Abstract][Full Text] [Related]  

  • 15. α-Synuclein negatively regulates protein kinase Cδ expression to suppress apoptosis in dopaminergic neurons by reducing p300 histone acetyltransferase activity.
    Jin H; Kanthasamy A; Ghosh A; Yang Y; Anantharam V; Kanthasamy AG
    J Neurosci; 2011 Feb; 31(6):2035-51. PubMed ID: 21307242
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Proteolytic activation of proapoptotic kinase protein kinase Cδ by tumor necrosis factor α death receptor signaling in dopaminergic neurons during neuroinflammation.
    Gordon R; Anantharam V; Kanthasamy AG; Kanthasamy A
    J Neuroinflammation; 2012 Apr; 9():82. PubMed ID: 22540228
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mechanistic Interplay Between Autophagy and Apoptotic Signaling in Endosulfan-Induced Dopaminergic Neurotoxicity: Relevance to the Adverse Outcome Pathway in Pesticide Neurotoxicity.
    Song C; Charli A; Luo J; Riaz Z; Jin H; Anantharam V; Kanthasamy A; Kanthasamy AG
    Toxicol Sci; 2019 Jun; 169(2):333-352. PubMed ID: 30796443
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Tyrosine phosphorylation regulates the proteolytic activation of protein kinase Cdelta in dopaminergic neuronal cells.
    Kaul S; Anantharam V; Yang Y; Choi CJ; Kanthasamy A; Kanthasamy AG
    J Biol Chem; 2005 Aug; 280(31):28721-30. PubMed ID: 15961393
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Androgens induce dopaminergic neurotoxicity via caspase-3-dependent activation of protein kinase Cdelta.
    Cunningham RL; Giuffrida A; Roberts JL
    Endocrinology; 2009 Dec; 150(12):5539-48. PubMed ID: 19837873
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The protein kinase C delta catalytic fragment targets Mcl-1 for degradation to trigger apoptosis.
    Sitailo LA; Tibudan SS; Denning MF
    J Biol Chem; 2006 Oct; 281(40):29703-10. PubMed ID: 16901898
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.