131 related articles for article (PubMed ID: 18298956)
1. Activation of the farnesoid X receptor represses PCSK9 expression in human hepatocytes.
Langhi C; Le May C; Kourimate S; Caron S; Staels B; Krempf M; Costet P; Cariou B
FEBS Lett; 2008 Mar; 582(6):949-55. PubMed ID: 18298956
[TBL] [Abstract][Full Text] [Related]
2. Curcumin enhances cell-surface LDLR level and promotes LDL uptake through downregulation of PCSK9 gene expression in HepG2 cells.
Tai MH; Chen PK; Chen PY; Wu MJ; Ho CT; Yen JH
Mol Nutr Food Res; 2014 Nov; 58(11):2133-45. PubMed ID: 25164566
[TBL] [Abstract][Full Text] [Related]
3. Bile acids induce the expression of the human peroxisome proliferator-activated receptor alpha gene via activation of the farnesoid X receptor.
Pineda Torra I; Claudel T; Duval C; Kosykh V; Fruchart JC; Staels B
Mol Endocrinol; 2003 Feb; 17(2):259-72. PubMed ID: 12554753
[TBL] [Abstract][Full Text] [Related]
4. Dual mechanisms for the fibrate-mediated repression of proprotein convertase subtilisin/kexin type 9.
Kourimate S; Le May C; Langhi C; Jarnoux AL; Ouguerram K; Zaïr Y; Nguyen P; Krempf M; Cariou B; Costet P
J Biol Chem; 2008 Apr; 283(15):9666-73. PubMed ID: 18245819
[TBL] [Abstract][Full Text] [Related]
5. Treatment with the natural FXR agonist chenodeoxycholic acid reduces clearance of plasma LDL whilst decreasing circulating PCSK9, lipoprotein(a) and apolipoprotein C-III.
Ghosh Laskar M; Eriksson M; Rudling M; Angelin B
J Intern Med; 2017 Jun; 281(6):575-585. PubMed ID: 28145001
[TBL] [Abstract][Full Text] [Related]
6. Suppression of Idol expression is an additional mechanism underlying statin-induced up-regulation of hepatic LDL receptor expression.
Dong B; Wu M; Cao A; Li H; Liu J
Int J Mol Med; 2011 Jan; 27(1):103-10. PubMed ID: 21069265
[TBL] [Abstract][Full Text] [Related]
7. Decreased plasma cholesterol and hypersensitivity to statins in mice lacking Pcsk9.
Rashid S; Curtis DE; Garuti R; Anderson NN; Bashmakov Y; Ho YK; Hammer RE; Moon YA; Horton JD
Proc Natl Acad Sci U S A; 2005 Apr; 102(15):5374-9. PubMed ID: 15805190
[TBL] [Abstract][Full Text] [Related]
8. The farnesoid X receptor induces very low density lipoprotein receptor gene expression.
Sirvent A; Claudel T; Martin G; Brozek J; Kosykh V; Darteil R; Hum DW; Fruchart JC; Staels B
FEBS Lett; 2004 May; 566(1-3):173-7. PubMed ID: 15147890
[TBL] [Abstract][Full Text] [Related]
9. Hepatic PCSK9 expression is regulated by nutritional status via insulin and sterol regulatory element-binding protein 1c.
Costet P; Cariou B; Lambert G; Lalanne F; Lardeux B; Jarnoux AL; Grefhorst A; Staels B; Krempf M
J Biol Chem; 2006 Mar; 281(10):6211-8. PubMed ID: 16407292
[TBL] [Abstract][Full Text] [Related]
10. Bile acids and lipoprotein metabolism: effects of cholestyramine and chenodeoxycholic acid on human hepatic mRNA expression.
Nilsson LM; Abrahamsson A; Sahlin S; Gustafsson U; Angelin B; Parini P; Einarsson C
Biochem Biophys Res Commun; 2007 Jun; 357(3):707-11. PubMed ID: 17448444
[TBL] [Abstract][Full Text] [Related]
11. Farnesoid x receptor ligands inhibit vascular smooth muscle cell inflammation and migration.
Li YT; Swales KE; Thomas GJ; Warner TD; Bishop-Bailey D
Arterioscler Thromb Vasc Biol; 2007 Dec; 27(12):2606-11. PubMed ID: 18029909
[TBL] [Abstract][Full Text] [Related]
12. Chenodeoxycholic acid-mediated activation of the farnesoid X receptor negatively regulates hydroxysteroid sulfotransferase.
Miyata M; Matsuda Y; Tsuchiya H; Kitada H; Akase T; Shimada M; Nagata K; Gonzalez FJ; Yamazoe Y
Drug Metab Pharmacokinet; 2006 Aug; 21(4):315-23. PubMed ID: 16946559
[TBL] [Abstract][Full Text] [Related]
13. Statins upregulate PCSK9, the gene encoding the proprotein convertase neural apoptosis-regulated convertase-1 implicated in familial hypercholesterolemia.
Dubuc G; Chamberland A; Wassef H; Davignon J; Seidah NG; Bernier L; Prat A
Arterioscler Thromb Vasc Biol; 2004 Aug; 24(8):1454-9. PubMed ID: 15178557
[TBL] [Abstract][Full Text] [Related]
14. Regulation of the proprotein convertase subtilisin/kexin type 9 in intestinal epithelial cells.
Leblond F; Seidah NG; Précourt LP; Delvin E; Dominguez M; Levy E
Am J Physiol Gastrointest Liver Physiol; 2009 Apr; 296(4):G805-15. PubMed ID: 19179626
[TBL] [Abstract][Full Text] [Related]
15. Farnesoid X receptor activation by chenodeoxycholic acid induces detoxifying enzymes through AMP-activated protein kinase and extracellular signal-regulated kinase 1/2-mediated phosphorylation of CCAAT/enhancer binding protein β.
Noh K; Kim YM; Kim YW; Kim SG
Drug Metab Dispos; 2011 Aug; 39(8):1451-9. PubMed ID: 21596890
[TBL] [Abstract][Full Text] [Related]
16. Strong induction of PCSK9 gene expression through HNF1alpha and SREBP2: mechanism for the resistance to LDL-cholesterol lowering effect of statins in dyslipidemic hamsters.
Dong B; Wu M; Li H; Kraemer FB; Adeli K; Seidah NG; Park SW; Liu J
J Lipid Res; 2010 Jun; 51(6):1486-95. PubMed ID: 20048381
[TBL] [Abstract][Full Text] [Related]
17. GW4064, an agonist of farnesoid X receptor, represses CYP3A4 expression in human hepatocytes by inducing small heterodimer partner expression.
Zhang S; Pan X; Jeong H
Drug Metab Dispos; 2015 May; 43(5):743-8. PubMed ID: 25725071
[TBL] [Abstract][Full Text] [Related]
18. Bile acid signaling through FXR induces intracellular adhesion molecule-1 expression in mouse liver and human hepatocytes.
Qin P; Borges-Marcucci LA; Evans MJ; Harnish DC
Am J Physiol Gastrointest Liver Physiol; 2005 Aug; 289(2):G267-73. PubMed ID: 15817812
[TBL] [Abstract][Full Text] [Related]
19. The mystery of PCSK9.
Attie AD
Arterioscler Thromb Vasc Biol; 2004 Aug; 24(8):1337-9. PubMed ID: 15297287
[No Abstract] [Full Text] [Related]
20. Human kininogen gene is transactivated by the farnesoid X receptor.
Zhao A; Lew JL; Huang L; Yu J; Zhang T; Hrywna Y; Thompson JR; de Pedro N; Blevins RA; Peláez F; Wright SD; Cui J
J Biol Chem; 2003 Aug; 278(31):28765-70. PubMed ID: 12761213
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
