378 related articles for article (PubMed ID: 18305219)
1. Targeting the p27 E3 ligase SCF(Skp2) results in p27- and Skp2-mediated cell-cycle arrest and activation of autophagy.
Chen Q; Xie W; Kuhn DJ; Voorhees PM; Lopez-Girona A; Mendy D; Corral LG; Krenitsky VP; Xu W; Moutouh-de Parseval L; Webb DR; Mercurio F; Nakayama KI; Nakayama K; Orlowski RZ
Blood; 2008 May; 111(9):4690-9. PubMed ID: 18305219
[TBL] [Abstract][Full Text] [Related]
2. Inhibitors of SCF-Skp2/Cks1 E3 ligase block estrogen-induced growth stimulation and degradation of nuclear p27kip1: therapeutic potential for endometrial cancer.
Pavlides SC; Huang KT; Reid DA; Wu L; Blank SV; Mittal K; Guo L; Rothenberg E; Rueda B; Cardozo T; Gold LI
Endocrinology; 2013 Nov; 154(11):4030-45. PubMed ID: 24035998
[TBL] [Abstract][Full Text] [Related]
3. High-throughput screening AlphaScreen assay for identification of small-molecule inhibitors of ubiquitin E3 ligase SCFSkp2-Cks1.
Ungermannova D; Lee J; Zhang G; Dallmann HG; McHenry CS; Liu X
J Biomol Screen; 2013 Sep; 18(8):910-20. PubMed ID: 23589337
[TBL] [Abstract][Full Text] [Related]
4. Pharmacogenomics and chemical library screens reveal a novel SCF
Malek E; Abdel-Malek MA; Jagannathan S; Vad N; Karns R; Jegga AG; Broyl A; van Duin M; Sonneveld P; Cottini F; Anderson KC; Driscoll JJ
Leukemia; 2017 Mar; 31(3):645-653. PubMed ID: 27677741
[TBL] [Abstract][Full Text] [Related]
5. Specific small molecule inhibitors of Skp2-mediated p27 degradation.
Wu L; Grigoryan AV; Li Y; Hao B; Pagano M; Cardozo TJ
Chem Biol; 2012 Dec; 19(12):1515-24. PubMed ID: 23261596
[TBL] [Abstract][Full Text] [Related]
6. Cell adhesion induces p27Kip1-associated cell-cycle arrest through down-regulation of the SCFSkp2 ubiquitin ligase pathway in mantle-cell and other non-Hodgkin B-cell lymphomas.
Lwin T; Hazlehurst LA; Dessureault S; Lai R; Bai W; Sotomayor E; Moscinski LC; Dalton WS; Tao J
Blood; 2007 Sep; 110(5):1631-8. PubMed ID: 17502456
[TBL] [Abstract][Full Text] [Related]
7. PTEN regulates the ubiquitin-dependent degradation of the CDK inhibitor p27(KIP1) through the ubiquitin E3 ligase SCF(SKP2).
Mamillapalli R; Gavrilova N; Mihaylova VT; Tsvetkov LM; Wu H; Zhang H; Sun H
Curr Biol; 2001 Feb; 11(4):263-7. PubMed ID: 11250155
[TBL] [Abstract][Full Text] [Related]
8. Oncostatin M induces growth arrest by inhibition of Skp2, Cks1, and cyclin A expression and induced p21 expression.
Halfter H; Friedrich M; Resch A; Kullmann M; Stögbauer F; Ringelstein EB; Hengst L
Cancer Res; 2006 Jul; 66(13):6530-9. PubMed ID: 16818624
[TBL] [Abstract][Full Text] [Related]
9. Estrogen and progesterone regulate p27kip1 levels via the ubiquitin-proteasome system: pathogenic and therapeutic implications for endometrial cancer.
Huang KT; Pavlides SC; Lecanda J; Blank SV; Mittal KR; Gold LI
PLoS One; 2012; 7(9):e46072. PubMed ID: 23029392
[TBL] [Abstract][Full Text] [Related]
10. Degradation of p27(Kip1) at the G(0)-G(1) transition mediated by a Skp2-independent ubiquitination pathway.
Hara T; Kamura T; Nakayama K; Oshikawa K; Hatakeyama S; Nakayama K
J Biol Chem; 2001 Dec; 276(52):48937-43. PubMed ID: 11682478
[TBL] [Abstract][Full Text] [Related]
11. Structural basis of the Cks1-dependent recognition of p27(Kip1) by the SCF(Skp2) ubiquitin ligase.
Hao B; Zheng N; Schulman BA; Wu G; Miller JJ; Pagano M; Pavletich NP
Mol Cell; 2005 Oct; 20(1):9-19. PubMed ID: 16209941
[TBL] [Abstract][Full Text] [Related]
12. Troglitazone induces p27Kip1-associated cell-cycle arrest through down-regulating Skp2 in human hepatoma cells.
Koga H; Harada M; Ohtsubo M; Shishido S; Kumemura H; Hanada S; Taniguchi E; Yamashita K; Kumashiro R; Ueno T; Sata M
Hepatology; 2003 May; 37(5):1086-96. PubMed ID: 12717389
[TBL] [Abstract][Full Text] [Related]
13. Inhibition of F-Box protein p45(SKP2) expression and stabilization of cyclin-dependent kinase inhibitor p27(KIP1) in vitamin D analog-treated cancer cells.
Lin R; Wang TT; Miller WH; White JH
Endocrinology; 2003 Mar; 144(3):749-53. PubMed ID: 12586749
[TBL] [Abstract][Full Text] [Related]
14. E3 Ubiquitin Ligases as Molecular Targets in Human Oral Cancers.
Masumoto K; Kitagawa M
Curr Cancer Drug Targets; 2016; 16(2):130-5. PubMed ID: 26560119
[TBL] [Abstract][Full Text] [Related]
15. Modification of cullin-1 by ubiquitin-like protein Nedd8 enhances the activity of SCF(skp2) toward p27(kip1).
Morimoto M; Nishida T; Honda R; Yasuda H
Biochem Biophys Res Commun; 2000 Apr; 270(3):1093-6. PubMed ID: 10772955
[TBL] [Abstract][Full Text] [Related]
16. CKS1B, overexpressed in aggressive disease, regulates multiple myeloma growth and survival through SKP2- and p27Kip1-dependent and -independent mechanisms.
Zhan F; Colla S; Wu X; Chen B; Stewart JP; Kuehl WM; Barlogie B; Shaughnessy JD
Blood; 2007 Jun; 109(11):4995-5001. PubMed ID: 17303695
[TBL] [Abstract][Full Text] [Related]
17. Sulforaphane down-regulates SKP2 to stabilize p27(KIP1) for inducing antiproliferation in human colon adenocarcinoma cells.
Chung YK; Chi-Hung Or R; Lu CH; Ouyang WT; Yang SY; Chang CC
J Biosci Bioeng; 2015 Jan; 119(1):35-42. PubMed ID: 25070589
[TBL] [Abstract][Full Text] [Related]
18. TGF-β activates APC through Cdh1 binding for Cks1 and Skp2 proteasomal destruction stabilizing p27kip1 for normal endometrial growth.
Pavlides SC; Lecanda J; Daubriac J; Pandya UM; Gama P; Blank S; Mittal K; Shukla P; Gold LI
Cell Cycle; 2016; 15(7):931-47. PubMed ID: 26963853
[TBL] [Abstract][Full Text] [Related]
19. p27(Kip1) ubiquitination and degradation is regulated by the SCF(Skp2) complex through phosphorylated Thr187 in p27.
Tsvetkov LM; Yeh KH; Lee SJ; Sun H; Zhang H
Curr Biol; 1999 Jun; 9(12):661-4. PubMed ID: 10375532
[TBL] [Abstract][Full Text] [Related]
20. Regulation of SCF(SKP2) ubiquitin E3 ligase assembly and p27(KIP1) proteolysis by the PTEN pathway and cyclin D1.
Jonason JH; Gavrilova N; Wu M; Zhang H; Sun H
Cell Cycle; 2007 Apr; 6(8):951-61. PubMed ID: 17438373
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
