These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
2. Transcriptional regulation of cytochrome p450 genes by the nuclear receptor hepatocyte nuclear factor 4-alpha. Jover R; Moya M; Gómez-Lechón MJ Curr Drug Metab; 2009 Jun; 10(5):508-19. PubMed ID: 19689247 [TBL] [Abstract][Full Text] [Related]
3. The xenobiotic-sensing nuclear receptors pregnane X receptor, constitutive androstane receptor, and orphan nuclear receptor hepatocyte nuclear factor 4alpha in the regulation of human steroid-/bile acid-sulfotransferase. Echchgadda I; Song CS; Oh T; Ahmed M; De La Cruz IJ; Chatterjee B Mol Endocrinol; 2007 Sep; 21(9):2099-111. PubMed ID: 17595319 [TBL] [Abstract][Full Text] [Related]
4. Involvement of hepatocyte nuclear factor 4 alpha in transcriptional regulation of the human pregnane X receptor gene in the human liver. Iwazaki N; Kobayashi K; Morimoto K; Hirano M; Kawashima S; Furihata T; Chiba K Drug Metab Pharmacokinet; 2008; 23(1):59-66. PubMed ID: 18305375 [TBL] [Abstract][Full Text] [Related]
5. HNF4α--role in drug metabolism and potential drug target? Hwang-Verslues WW; Sladek FM Curr Opin Pharmacol; 2010 Dec; 10(6):698-705. PubMed ID: 20833107 [TBL] [Abstract][Full Text] [Related]
6. Role of the hepatocyte nuclear factor 4alpha in control of the pregnane X receptor during fetal liver development. Kamiya A; Inoue Y; Gonzalez FJ Hepatology; 2003 Jun; 37(6):1375-84. PubMed ID: 12774017 [TBL] [Abstract][Full Text] [Related]
7. Hepatocyte Nuclear Factor 4α Controls Iron Metabolism and Regulates Transferrin Receptor 2 in Mouse Liver. Matsuo S; Ogawa M; Muckenthaler MU; Mizui Y; Sasaki S; Fujimura T; Takizawa M; Ariga N; Ozaki H; Sakaguchi M; Gonzalez FJ; Inoue Y J Biol Chem; 2015 Dec; 290(52):30855-65. PubMed ID: 26527688 [TBL] [Abstract][Full Text] [Related]
8. Human CYP2C8 is transcriptionally regulated by the nuclear receptors constitutive androstane receptor, pregnane X receptor, glucocorticoid receptor, and hepatic nuclear factor 4alpha. Ferguson SS; Chen Y; LeCluyse EL; Negishi M; Goldstein JA Mol Pharmacol; 2005 Sep; 68(3):747-57. PubMed ID: 15933212 [TBL] [Abstract][Full Text] [Related]
9. Nuclear receptor coactivator 6 mediates the synergistic activation of human cytochrome P-450 2C9 by the constitutive androstane receptor and hepatic nuclear factor-4alpha. Surapureddi S; Rana R; Reddy JK; Goldstein JA Mol Pharmacol; 2008 Sep; 74(3):913-23. PubMed ID: 18552123 [TBL] [Abstract][Full Text] [Related]
10. Rifampicin induction of CYP3A4 requires pregnane X receptor cross talk with hepatocyte nuclear factor 4alpha and coactivators, and suppression of small heterodimer partner gene expression. Li T; Chiang JY Drug Metab Dispos; 2006 May; 34(5):756-64. PubMed ID: 16455805 [TBL] [Abstract][Full Text] [Related]
11. Farnesoid X receptor regulates SULT1E1 expression through inhibition of PGC1α binding to HNF4α. Wang S; Yuan X; Lu D; Guo L; Wu B Biochem Pharmacol; 2017 Dec; 145():202-209. PubMed ID: 28912067 [TBL] [Abstract][Full Text] [Related]
12. Characterization of glucocorticoid receptor and hepatocyte nuclear factor 4alpha (HNF4alpha) binding to the hnf4alpha gene in the liver. Bailly A; Briançon N; Weiss MC Biochimie; 2009 Sep; 91(9):1095-103. PubMed ID: 19540905 [TBL] [Abstract][Full Text] [Related]
13. CCAAT/enhancer-binding protein alpha (C/EBPalpha) and hepatocyte nuclear factor 4alpha (HNF4alpha) synergistically cooperate with constitutive androstane receptor to transactivate the human cytochrome P450 2B6 (CYP2B6) gene: application to the development of a metabolically competent human hepatic cell model. Benet M; Lahoz A; Guzmán C; Castell JV; Jover R J Biol Chem; 2010 Sep; 285(37):28457-71. PubMed ID: 20622021 [TBL] [Abstract][Full Text] [Related]
14. Hepatocyte nuclear factor 4 alpha and farnesoid X receptor co-regulates gene transcription in mouse livers on a genome-wide scale. Thomas AM; Hart SN; Li G; Lu H; Fang Y; Fang J; Zhong XB; Guo GL Pharm Res; 2013 Sep; 30(9):2188-98. PubMed ID: 23462932 [TBL] [Abstract][Full Text] [Related]
15. Hepatocyte nuclear factor 4α regulates the expression of the murine pyruvate carboxylase gene through the HNF4-specific binding motif in its proximal promoter. Chavalit T; Rojvirat P; Muangsawat S; Jitrapakdee S Biochim Biophys Acta; 2013 Oct; 1829(10):987-99. PubMed ID: 23665043 [TBL] [Abstract][Full Text] [Related]
16. Hepatitis C virus suppresses Hepatocyte Nuclear Factor 4 alpha, a key regulator of hepatocellular carcinoma. Vallianou I; Dafou D; Vassilaki N; Mavromara P; Hadzopoulou-Cladaras M Int J Biochem Cell Biol; 2016 Sep; 78():315-326. PubMed ID: 27477312 [TBL] [Abstract][Full Text] [Related]
17. Regulation of mouse hepatic alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase, a key enzyme in the tryptophan-nicotinamide adenine dinucleotide pathway, by hepatocyte nuclear factor 4alpha and peroxisome proliferator-activated receptor alpha. Shin M; Kim I; Inoue Y; Kimura S; Gonzalez FJ Mol Pharmacol; 2006 Oct; 70(4):1281-90. PubMed ID: 16807375 [TBL] [Abstract][Full Text] [Related]
18. Transcriptional activation of CYP2C9, CYP1A1, and CYP1A2 by hepatocyte nuclear factor 4alpha requires coactivators peroxisomal proliferator activated receptor-gamma coactivator 1alpha and steroid receptor coactivator 1. Martínez-Jiménez CP; Castell JV; Gómez-Lechón MJ; Jover R Mol Pharmacol; 2006 Nov; 70(5):1681-92. PubMed ID: 16882880 [TBL] [Abstract][Full Text] [Related]
19. Diurnal regulation of the early growth response 1 (Egr-1) protein expression by hepatocyte nuclear factor 4alpha (HNF4alpha) and small heterodimer partner (SHP) cross-talk in liver fibrosis. Zhang Y; Bonzo JA; Gonzalez FJ; Wang L J Biol Chem; 2011 Aug; 286(34):29635-43. PubMed ID: 21725089 [TBL] [Abstract][Full Text] [Related]
20. HNF4α in Hepatocyte Health and Disease. Kotulkar M; Robarts DR; Apte U Semin Liver Dis; 2023 May; 43(2):234-244. PubMed ID: 37216979 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]