BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

709 related articles for article (PubMed ID: 18308615)

  • 1. IkappaB kinase beta (IKKbeta/IKK2/IKBKB)--a key molecule in signaling to the transcription factor NF-kappaB.
    Schmid JA; Birbach A
    Cytokine Growth Factor Rev; 2008 Apr; 19(2):157-65. PubMed ID: 18308615
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Regulation and function of IKK and IKK-related kinases.
    Häcker H; Karin M
    Sci STKE; 2006 Oct; 2006(357):re13. PubMed ID: 17047224
    [TBL] [Abstract][Full Text] [Related]  

  • 3. NF-kappaB activation elicited by ionizing radiation is proapoptotic in testis.
    Rasoulpour RJ; Boekelheide K
    Biol Reprod; 2007 Feb; 76(2):279-85. PubMed ID: 17123945
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The role of ubiquitin in NF-kappaB regulatory pathways.
    Skaug B; Jiang X; Chen ZJ
    Annu Rev Biochem; 2009; 78():769-96. PubMed ID: 19489733
    [TBL] [Abstract][Full Text] [Related]  

  • 5. IkappaB kinase complexes: gateways to NF-kappaB activation and transcription.
    Scheidereit C
    Oncogene; 2006 Oct; 25(51):6685-705. PubMed ID: 17072322
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A selective small molecule IkappaB Kinase beta inhibitor blocks nuclear factor kappaB-mediated inflammatory responses in human fibroblast-like synoviocytes, chondrocytes, and mast cells.
    Wen D; Nong Y; Morgan JG; Gangurde P; Bielecki A; Dasilva J; Keaveney M; Cheng H; Fraser C; Schopf L; Hepperle M; Harriman G; Jaffee BD; Ocain TD; Xu Y
    J Pharmacol Exp Ther; 2006 Jun; 317(3):989-1001. PubMed ID: 16525037
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Validation of the anti-inflammatory properties of small-molecule IkappaB Kinase (IKK)-2 inhibitors by comparison with adenoviral-mediated delivery of dominant-negative IKK1 and IKK2 in human airways smooth muscle.
    Catley MC; Sukkar MB; Chung KF; Jaffee B; Liao SM; Coyle AJ; Haddad el-B; Barnes PJ; Newton R
    Mol Pharmacol; 2006 Aug; 70(2):697-705. PubMed ID: 16687566
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Dynamic protein complexes regulate NF-kappaB signaling.
    Wegener E; Krappmann D
    Handb Exp Pharmacol; 2008; (186):237-59. PubMed ID: 18491055
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Phosphorylation-dependent association of the G4-1/G5PR regulatory subunit with IKKβ negatively modulates NF-κB activation through recruitment of protein phosphatase 5.
    Chiang CW; Liu WK; Chiang CW; Chou CK
    Biochem J; 2011 Jan; 433(1):187-96. PubMed ID: 20925653
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Induction of apoptosis in estrogen receptor-negative breast cancer cells by natural and synthetic cyclopentenones: role of the IkappaB kinase/nuclear factor-kappaB pathway.
    Ciucci A; Gianferretti P; Piva R; Guyot T; Snape TJ; Roberts SM; Santoro MG
    Mol Pharmacol; 2006 Nov; 70(5):1812-21. PubMed ID: 16908599
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Inhibitor of nuclear factor kappaB kinase beta is a key regulator of synovial inflammation.
    Tak PP; Gerlag DM; Aupperle KR; van de Geest DA; Overbeek M; Bennett BL; Boyle DL; Manning AM; Firestein GS
    Arthritis Rheum; 2001 Aug; 44(8):1897-907. PubMed ID: 11508443
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Artemisolide is a typical inhibitor of IkappaB kinase beta targeting cysteine-179 residue and down-regulates NF-kappaB-dependent TNF-alpha expression in LPS-activated macrophages.
    Kim BH; Lee JY; Seo JH; Lee HY; Ryu SY; Ahn BW; Lee CK; Hwang BY; Han SB; Kim Y
    Biochem Biophys Res Commun; 2007 Sep; 361(3):593-8. PubMed ID: 17669364
    [TBL] [Abstract][Full Text] [Related]  

  • 13. HSCARG inhibits activation of NF-kappaB by interacting with IkappaB kinase-beta.
    Gan Q; Li T; Hu B; Lian M; Zheng X
    J Cell Sci; 2009 Nov; 122(Pt 22):4081-8. PubMed ID: 19843583
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The NF-kappaB transcription factor pathway as a therapeutic target in cancer: methods for detection of NF-kappaB activity.
    Mauro C; Zazzeroni F; Papa S; Bubici C; Franzoso G
    Methods Mol Biol; 2009; 512():169-207. PubMed ID: 19347278
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Protein kinase R, IkappaB kinase-beta and NF-kappaB are required for human rhinovirus induced pro-inflammatory cytokine production in bronchial epithelial cells.
    Edwards MR; Hewson CA; Laza-Stanca V; Lau HT; Mukaida N; Hershenson MB; Johnston SL
    Mol Immunol; 2007 Mar; 44(7):1587-97. PubMed ID: 16989899
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Extending the nuclear roles of IkappaB kinase subunits.
    Gloire G; Dejardin E; Piette J
    Biochem Pharmacol; 2006 Oct; 72(9):1081-9. PubMed ID: 16846590
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Epithelial NEMO links innate immunity to chronic intestinal inflammation.
    Nenci A; Becker C; Wullaert A; Gareus R; van Loo G; Danese S; Huth M; Nikolaev A; Neufert C; Madison B; Gumucio D; Neurath MF; Pasparakis M
    Nature; 2007 Mar; 446(7135):557-61. PubMed ID: 17361131
    [TBL] [Abstract][Full Text] [Related]  

  • 18. N-tosyl-L-phenylalanine chloromethyl ketone inhibits NF-kappaB activation by blocking specific cysteine residues of IkappaB kinase beta and p65/RelA.
    Ha KH; Byun MS; Choi J; Jeong J; Lee KJ; Jue DM
    Biochemistry; 2009 Aug; 48(30):7271-8. PubMed ID: 19591457
    [TBL] [Abstract][Full Text] [Related]  

  • 19. NF-kappaB and IKK as therapeutic targets in cancer.
    Kim HJ; Hawke N; Baldwin AS
    Cell Death Differ; 2006 May; 13(5):738-47. PubMed ID: 16485028
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Phosphorylation of NF-kappaB and IkappaB proteins: implications in cancer and inflammation.
    Viatour P; Merville MP; Bours V; Chariot A
    Trends Biochem Sci; 2005 Jan; 30(1):43-52. PubMed ID: 15653325
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 36.