BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

223 related articles for article (PubMed ID: 18313386)

  • 1. Bcl2 negatively regulates DNA double-strand-break repair through a nonhomologous end-joining pathway.
    Wang Q; Gao F; May WS; Zhang Y; Flagg T; Deng X
    Mol Cell; 2008 Feb; 29(4):488-98. PubMed ID: 18313386
    [TBL] [Abstract][Full Text] [Related]  

  • 2. c-Myc suppression of DNA double-strand break repair.
    Li Z; Owonikoko TK; Sun SY; Ramalingam SS; Doetsch PW; Xiao ZQ; Khuri FR; Curran WJ; Deng X
    Neoplasia; 2012 Dec; 14(12):1190-202. PubMed ID: 23308051
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A nonhomologous end-joining pathway is required for protein phosphatase 2A promotion of DNA double-strand break repair.
    Wang Q; Gao F; Wang T; Flagg T; Deng X
    Neoplasia; 2009 Oct; 11(10):1012-21. PubMed ID: 19794960
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Ku regulates the non-homologous end joining pathway choice of DNA double-strand break repair in human somatic cells.
    Fattah F; Lee EH; Weisensel N; Wang Y; Lichter N; Hendrickson EA
    PLoS Genet; 2010 Feb; 6(2):e1000855. PubMed ID: 20195511
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Genetic analysis of the DNA-dependent protein kinase reveals an inhibitory role of Ku in late S-G2 phase DNA double-strand break repair.
    Fukushima T; Takata M; Morrison C; Araki R; Fujimori A; Abe M; Tatsumi K; Jasin M; Dhar PK; Sonoda E; Chiba T; Takeda S
    J Biol Chem; 2001 Nov; 276(48):44413-8. PubMed ID: 11577093
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Different types of V(D)J recombination and end-joining defects in DNA double-strand break repair mutant mammalian cells.
    Verkaik NS; Esveldt-van Lange RE; van Heemst D; Brüggenwirth HT; Hoeijmakers JH; Zdzienicka MZ; van Gent DC
    Eur J Immunol; 2002 Mar; 32(3):701-9. PubMed ID: 11870614
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Biochemical evidence for Ku-independent backup pathways of NHEJ.
    Wang H; Perrault AR; Takeda Y; Qin W; Wang H; Iliakis G
    Nucleic Acids Res; 2003 Sep; 31(18):5377-88. PubMed ID: 12954774
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mechanisms of DNA double strand break repair and chromosome aberration formation.
    Iliakis G; Wang H; Perrault AR; Boecker W; Rosidi B; Windhofer F; Wu W; Guan J; Terzoudi G; Pantelias G
    Cytogenet Genome Res; 2004; 104(1-4):14-20. PubMed ID: 15162010
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Papillary and muscle invasive bladder tumors with distinct genomic stability profiles have different DNA repair fidelity and KU DNA-binding activities.
    Bentley J; L'Hôte C; Platt F; Hurst CD; Lowery J; Taylor C; Sak SC; Harnden P; Knowles MA; Kiltie AE
    Genes Chromosomes Cancer; 2009 Apr; 48(4):310-21. PubMed ID: 19105236
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Bcl2 inhibits recruitment of Mre11 complex to DNA double-strand breaks in response to high-linear energy transfer radiation.
    Xie M; Park D; You S; Li R; Owonikoko TK; Wang Y; Doetsch PW; Deng X
    Nucleic Acids Res; 2015 Jan; 43(2):960-72. PubMed ID: 25567982
    [TBL] [Abstract][Full Text] [Related]  

  • 11. An Intrinsically Disordered APLF Links Ku, DNA-PKcs, and XRCC4-DNA Ligase IV in an Extended Flexible Non-homologous End Joining Complex.
    Hammel M; Yu Y; Radhakrishnan SK; Chokshi C; Tsai MS; Matsumoto Y; Kuzdovich M; Remesh SG; Fang S; Tomkinson AE; Lees-Miller SP; Tainer JA
    J Biol Chem; 2016 Dec; 291(53):26987-27006. PubMed ID: 27875301
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Functional redundancy between the XLF and DNA-PKcs DNA repair factors in V(D)J recombination and nonhomologous DNA end joining.
    Oksenych V; Kumar V; Liu X; Guo C; Schwer B; Zha S; Alt FW
    Proc Natl Acad Sci U S A; 2013 Feb; 110(6):2234-9. PubMed ID: 23345432
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Ku70-deficient embryonic stem cells have increased ionizing radiosensitivity, defective DNA end-binding activity, and inability to support V(D)J recombination.
    Gu Y; Jin S; Gao Y; Weaver DT; Alt FW
    Proc Natl Acad Sci U S A; 1997 Jul; 94(15):8076-81. PubMed ID: 9223317
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Complementation of the ionizing radiation sensitivity, DNA end binding, and V(D)J recombination defects of double-strand break repair mutants by the p86 Ku autoantigen.
    Boubnov NV; Hall KT; Wills Z; Lee SE; He DM; Benjamin DM; Pulaski CR; Band H; Reeves W; Hendrickson EA
    Proc Natl Acad Sci U S A; 1995 Jan; 92(3):890-4. PubMed ID: 7846073
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Double-strand break repair by Ku70 requires heterodimerization with Ku80 and DNA binding functions.
    Jin S; Weaver DT
    EMBO J; 1997 Nov; 16(22):6874-85. PubMed ID: 9362500
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Ku70 suppresses alternative end joining in G1-arrested progenitor B cells.
    Liang Z; Kumar V; Le Bouteiller M; Zurita J; Kenrick J; Lin SG; Lou J; Hu J; Ye AY; Boboila C; Alt FW; Frock RL
    Proc Natl Acad Sci U S A; 2021 May; 118(21):. PubMed ID: 34006647
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Suppression of nonhomologous end joining repair by overexpression of HMGA2.
    Li AY; Boo LM; Wang SY; Lin HH; Wang CC; Yen Y; Chen BP; Chen DJ; Ann DK
    Cancer Res; 2009 Jul; 69(14):5699-706. PubMed ID: 19549901
    [TBL] [Abstract][Full Text] [Related]  

  • 18. DNA-dependent protein kinase regulates DNA end resection in concert with Mre11-Rad50-Nbs1 (MRN) and ataxia telangiectasia-mutated (ATM).
    Zhou Y; Paull TT
    J Biol Chem; 2013 Dec; 288(52):37112-25. PubMed ID: 24220101
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The C terminus of Ku80 activates the DNA-dependent protein kinase catalytic subunit.
    Singleton BK; Torres-Arzayus MI; Rottinghaus ST; Taccioli GE; Jeggo PA
    Mol Cell Biol; 1999 May; 19(5):3267-77. PubMed ID: 10207052
    [TBL] [Abstract][Full Text] [Related]  

  • 20. BCL2-overexpressing prostate cancer cells rely on PARP1-dependent end-joining and are sensitive to combined PARP inhibitor and radiation therapy.
    Oing C; Tennstedt P; Simon R; Volquardsen J; Borgmann K; Bokemeyer C; Petersen C; Dikomey E; Rothkamm K; Mansour WY
    Cancer Lett; 2018 Jun; 423():60-70. PubMed ID: 29526801
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.