BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

476 related articles for article (PubMed ID: 18316032)

  • 1. ATF4-mediated induction of 4E-BP1 contributes to pancreatic beta cell survival under endoplasmic reticulum stress.
    Yamaguchi S; Ishihara H; Yamada T; Tamura A; Usui M; Tominaga R; Munakata Y; Satake C; Katagiri H; Tashiro F; Aburatani H; Tsukiyama-Kohara K; Miyazaki J; Sonenberg N; Oka Y
    Cell Metab; 2008 Mar; 7(3):269-76. PubMed ID: 18316032
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The JNK pathway modulates expression and phosphorylation of 4E-BP1 in MIN6 pancreatic beta-cells under oxidative stress conditions.
    Tominaga R; Yamaguchi S; Satake C; Usui M; Tanji Y; Kondo K; Katagiri H; Oka Y; Ishihara H
    Cell Biochem Funct; 2010 Jul; 28(5):387-93. PubMed ID: 20589738
    [TBL] [Abstract][Full Text] [Related]  

  • 3. WFS1-deficiency increases endoplasmic reticulum stress, impairs cell cycle progression and triggers the apoptotic pathway specifically in pancreatic beta-cells.
    Yamada T; Ishihara H; Tamura A; Takahashi R; Yamaguchi S; Takei D; Tokita A; Satake C; Tashiro F; Katagiri H; Aburatani H; Miyazaki J; Oka Y
    Hum Mol Genet; 2006 May; 15(10):1600-9. PubMed ID: 16571599
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Expressional and functional studies of Wolframin, the gene function deficient in Wolfram syndrome, in mice and patient cells.
    Philbrook C; Fritz E; Weiher H
    Exp Gerontol; 2005; 40(8-9):671-8. PubMed ID: 16087305
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Protective role for nitric oxide during the endoplasmic reticulum stress response in pancreatic beta-cells.
    Kitiphongspattana K; Khan TA; Ishii-Schrade K; Roe MW; Philipson LH; Gaskins HR
    Am J Physiol Endocrinol Metab; 2007 Jun; 292(6):E1543-54. PubMed ID: 17264231
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Protection of pancreatic beta-cells by exendin-4 may involve the reduction of endoplasmic reticulum stress; in vivo and in vitro studies.
    Tsunekawa S; Yamamoto N; Tsukamoto K; Itoh Y; Kaneko Y; Kimura T; Ariyoshi Y; Miura Y; Oiso Y; Niki I
    J Endocrinol; 2007 Apr; 193(1):65-74. PubMed ID: 17400804
    [TBL] [Abstract][Full Text] [Related]  

  • 7. L-serine deficiency caused by genetic Phgdh deletion leads to robust induction of 4E-BP1 and subsequent repression of translation initiation in the developing central nervous system.
    Sayano T; Kawakami Y; Kusada W; Suzuki T; Kawano Y; Watanabe A; Takashima K; Arimoto Y; Esaki K; Wada A; Yoshizawa F; Watanabe M; Okamoto M; Hirabayashi Y; Furuya S
    FEBS J; 2013 Mar; 280(6):1502-17. PubMed ID: 23350942
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Reduced insulin signaling and endoplasmic reticulum stress act synergistically to deteriorate pancreatic beta cell function.
    Matsuda T; Kido Y; Uchida T; Kasuga M
    Kobe J Med Sci; 2008 Jul; 54(2):E114-21. PubMed ID: 18772613
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Nitric oxide-induced apoptosis in pancreatic beta cells is mediated by the endoplasmic reticulum stress pathway.
    Oyadomari S; Takeda K; Takiguchi M; Gotoh T; Matsumoto M; Wada I; Akira S; Araki E; Mori M
    Proc Natl Acad Sci U S A; 2001 Sep; 98(19):10845-50. PubMed ID: 11526215
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Activating transcription factor 4 and CCAAT/enhancer-binding protein-beta negatively regulate the mammalian target of rapamycin via Redd1 expression in response to oxidative and endoplasmic reticulum stress.
    Jin HO; Seo SK; Woo SH; Kim ES; Lee HC; Yoo DH; An S; Choe TB; Lee SJ; Hong SI; Rhee CH; Kim JI; Park IC
    Free Radic Biol Med; 2009 Apr; 46(8):1158-67. PubMed ID: 19439225
    [TBL] [Abstract][Full Text] [Related]  

  • 11. High expression rates of human islet amyloid polypeptide induce endoplasmic reticulum stress mediated beta-cell apoptosis, a characteristic of humans with type 2 but not type 1 diabetes.
    Huang CJ; Lin CY; Haataja L; Gurlo T; Butler AE; Rizza RA; Butler PC
    Diabetes; 2007 Aug; 56(8):2016-27. PubMed ID: 17475933
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Atf6α-null mice are glucose intolerant due to pancreatic β-cell failure on a high-fat diet but partially resistant to diet-induced insulin resistance.
    Usui M; Yamaguchi S; Tanji Y; Tominaga R; Ishigaki Y; Fukumoto M; Katagiri H; Mori K; Oka Y; Ishihara H
    Metabolism; 2012 Aug; 61(8):1118-28. PubMed ID: 22386934
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Wolfram syndrome 1 gene (WFS1) product localizes to secretory granules and determines granule acidification in pancreatic beta-cells.
    Hatanaka M; Tanabe K; Yanai A; Ohta Y; Kondo M; Akiyama M; Shinoda K; Oka Y; Tanizawa Y
    Hum Mol Genet; 2011 Apr; 20(7):1274-84. PubMed ID: 21199859
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Elevated sensitivity to diet-induced obesity and insulin resistance in mice lacking 4E-BP1 and 4E-BP2.
    Le Bacquer O; Petroulakis E; Paglialunga S; Poulin F; Richard D; Cianflone K; Sonenberg N
    J Clin Invest; 2007 Feb; 117(2):387-96. PubMed ID: 17273556
    [TBL] [Abstract][Full Text] [Related]  

  • 15. ERp46 is reduced by high glucose and regulates insulin content in pancreatic beta-cells.
    Alberti A; Karamessinis P; Peroulis M; Kypreou K; Kavvadas P; Pagakis S; Politis PK; Charonis A
    Am J Physiol Endocrinol Metab; 2009 Sep; 297(3):E812-21. PubMed ID: 19622788
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A PDX1-ATF transcriptional complex governs β cell survival during stress.
    Juliana CA; Yang J; Cannon CE; Good AL; Haemmerle MW; Stoffers DA
    Mol Metab; 2018 Nov; 17():39-48. PubMed ID: 30174228
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Up-regulation of gamma-synuclein contributes to cancer cell survival under endoplasmic reticulum stress.
    Hua H; Xu L; Wang J; Jing J; Luo T; Jiang Y
    J Pathol; 2009 Mar; 217(4):507-15. PubMed ID: 19009586
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Transcriptional regulation of the endoplasmic reticulum stress gene chop in pancreatic insulin-producing cells.
    Pirot P; Ortis F; Cnop M; Ma Y; Hendershot LM; Eizirik DL; Cardozo AK
    Diabetes; 2007 Apr; 56(4):1069-77. PubMed ID: 17395747
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Targeted disruption of the Chop gene delays endoplasmic reticulum stress-mediated diabetes.
    Oyadomari S; Koizumi A; Takeda K; Gotoh T; Akira S; Araki E; Mori M
    J Clin Invest; 2002 Feb; 109(4):525-32. PubMed ID: 11854325
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Inhibition of 4E-BP1 sensitizes U87 glioblastoma xenograft tumors to irradiation by decreasing hypoxia tolerance.
    Dubois L; Magagnin MG; Cleven AH; Weppler SA; Grenacher B; Landuyt W; Lieuwes N; Lambin P; Gorr TA; Koritzinsky M; Wouters BG
    Int J Radiat Oncol Biol Phys; 2009 Mar; 73(4):1219-27. PubMed ID: 19251093
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 24.