BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

147 related articles for article (PubMed ID: 18316628)

  • 1. Dual targeting of the proteasome regulates survival and homing in Waldenstrom macroglobulinemia.
    Roccaro AM; Leleu X; Sacco A; Jia X; Melhem M; Moreau AS; Ngo HT; Runnels J; Azab A; Azab F; Burwick N; Farag M; Treon SP; Palladino MA; Hideshima T; Chauhan D; Anderson KC; Ghobrial IM
    Blood; 2008 May; 111(9):4752-63. PubMed ID: 18316628
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Carfilzomib-dependent selective inhibition of the chymotrypsin-like activity of the proteasome leads to antitumor activity in Waldenstrom's Macroglobulinemia.
    Sacco A; Aujay M; Morgan B; Azab AK; Maiso P; Liu Y; Zhang Y; Azab F; Ngo HT; Issa GC; Quang P; Roccaro AM; Ghobrial IM
    Clin Cancer Res; 2011 Apr; 17(7):1753-64. PubMed ID: 21355079
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Targeting NF-kappaB in Waldenstrom macroglobulinemia.
    Leleu X; Eeckhoute J; Jia X; Roccaro AM; Moreau AS; Farag M; Sacco A; Ngo HT; Runnels J; Melhem MR; Burwick N; Azab A; Azab F; Hunter Z; Hatjiharissi E; Carrasco DR; Treon SP; Witzig TE; Hideshima T; Brown M; Anderson KC; Ghobrial IM
    Blood; 2008 May; 111(10):5068-77. PubMed ID: 18334673
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mechanisms of activity of the TORC1 inhibitor everolimus in Waldenstrom macroglobulinemia.
    Roccaro AM; Sacco A; Jia X; Banwait R; Maiso P; Azab F; Flores L; Manier S; Azab AK; Ghobrial IM
    Clin Cancer Res; 2012 Dec; 18(24):6609-22. PubMed ID: 23048077
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Combination of proteasome inhibitors bortezomib and NPI-0052 trigger in vivo synergistic cytotoxicity in multiple myeloma.
    Chauhan D; Singh A; Brahmandam M; Podar K; Hideshima T; Richardson P; Munshi N; Palladino MA; Anderson KC
    Blood; 2008 Feb; 111(3):1654-64. PubMed ID: 18006697
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Selective inhibition of chymotrypsin-like activity of the immunoproteasome and constitutive proteasome in Waldenstrom macroglobulinemia.
    Roccaro AM; Sacco A; Aujay M; Ngo HT; Azab AK; Azab F; Quang P; Maiso P; Runnels J; Anderson KC; Demo S; Ghobrial IM
    Blood; 2010 May; 115(20):4051-60. PubMed ID: 20110419
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A novel orally active proteasome inhibitor induces apoptosis in multiple myeloma cells with mechanisms distinct from Bortezomib.
    Chauhan D; Catley L; Li G; Podar K; Hideshima T; Velankar M; Mitsiades C; Mitsiades N; Yasui H; Letai A; Ovaa H; Berkers C; Nicholson B; Chao TH; Neuteboom ST; Richardson P; Palladino MA; Anderson KC
    Cancer Cell; 2005 Nov; 8(5):407-19. PubMed ID: 16286248
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Role of proteasome inhibition in Waldenström's macroglobulinemia.
    Roccaro AM; Sacco A; Leleu X; Azab AK; Azab F; Runnels J; Jia X; Ngo HT; Melhem M; Moreau AS; Ghobrial IM
    Clin Lymphoma Myeloma; 2009 Mar; 9(1):94-6. PubMed ID: 19362985
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The proteasome inhibitor NPI-0052 is a more effective inducer of apoptosis than bortezomib in lymphocytes from patients with chronic lymphocytic leukemia.
    Ruiz S; Krupnik Y; Keating M; Chandra J; Palladino M; McConkey D
    Mol Cancer Ther; 2006 Jul; 5(7):1836-43. PubMed ID: 16891470
    [TBL] [Abstract][Full Text] [Related]  

  • 10. microRNA expression in the biology, prognosis, and therapy of Waldenström macroglobulinemia.
    Roccaro AM; Sacco A; Chen C; Runnels J; Leleu X; Azab F; Azab AK; Jia X; Ngo HT; Melhem MR; Burwick N; Varticovski L; Novina CD; Rollins BJ; Anderson KC; Ghobrial IM
    Blood; 2009 Apr; 113(18):4391-402. PubMed ID: 19074725
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Resveratrol exerts antiproliferative activity and induces apoptosis in Waldenström's macroglobulinemia.
    Roccaro AM; Leleu X; Sacco A; Moreau AS; Hatjiharissi E; Jia X; Xu L; Ciccarelli B; Patterson CJ; Ngo HT; Russo D; Vacca A; Dammacco F; Anderson KC; Ghobrial IM; Treon SP
    Clin Cancer Res; 2008 Mar; 14(6):1849-58. PubMed ID: 18347188
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Inhibition of Yin Yang 1-dependent repressor activity of DR5 transcription and expression by the novel proteasome inhibitor NPI-0052 contributes to its TRAIL-enhanced apoptosis in cancer cells.
    Baritaki S; Suzuki E; Umezawa K; Spandidos DA; Berenson J; Daniels TR; Penichet ML; Jazirehi AR; Palladino M; Bonavida B
    J Immunol; 2008 May; 180(9):6199-210. PubMed ID: 18424742
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Bortezomib as a treatment option in patients with Waldenström macroglobulinemia.
    Dimopoulos MA; Chen C; Kastritis E; Gavriatopoulou M; Treon SP
    Clin Lymphoma Myeloma Leuk; 2010 Apr; 10(2):110-7. PubMed ID: 20371443
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Caspase-8 dependent histone acetylation by a novel proteasome inhibitor, NPI-0052: a mechanism for synergy in leukemia cells.
    Miller CP; Rudra S; Keating MJ; Wierda WG; Palladino M; Chandra J
    Blood; 2009 Apr; 113(18):4289-99. PubMed ID: 19182209
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Protein kinase C inhibitor enzastaurin induces in vitro and in vivo antitumor activity in Waldenstrom macroglobulinemia.
    Moreau AS; Jia X; Ngo HT; Leleu X; O'Sullivan G; Alsayed Y; Leontovich A; Podar K; Kutok J; Daley J; Lazo-Kallanian S; Hatjiharissi E; Raab MS; Xu L; Treon SP; Hideshima T; Anderson KC; Ghobrial IM
    Blood; 2007 Jun; 109(11):4964-72. PubMed ID: 17284528
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Antiproliferative and proapoptotic effects of proteasome inhibitors and their combination with histone deacetylase inhibitors on leukemia cells.
    Fuchs O; Provaznikova D; Marinov I; Kuzelova K; Spicka I
    Cardiovasc Hematol Disord Drug Targets; 2009 Mar; 9(1):62-77. PubMed ID: 19275578
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The Akt pathway regulates survival and homing in Waldenstrom macroglobulinemia.
    Leleu X; Jia X; Runnels J; Ngo HT; Moreau AS; Farag M; Spencer JA; Pitsillides CM; Hatjiharissi E; Roccaro A; O'Sullivan G; McMillin DW; Moreno D; Kiziltepe T; Carrasco R; Treon SP; Hideshima T; Anderson KC; Lin CP; Ghobrial IM
    Blood; 2007 Dec; 110(13):4417-26. PubMed ID: 17761832
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Pivotal roles of snail inhibition and RKIP induction by the proteasome inhibitor NPI-0052 in tumor cell chemoimmunosensitization.
    Baritaki S; Yeung K; Palladino M; Berenson J; Bonavida B
    Cancer Res; 2009 Nov; 69(21):8376-85. PubMed ID: 19843864
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Proteasome Inhibitors in Waldenström Macroglobulinemia.
    Kastritis E; Dimopoulos MA
    Hematol Oncol Clin North Am; 2018 Oct; 32(5):829-840. PubMed ID: 30190021
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Bortezomib and Waldenstrom's macroglobulinemia.
    Pascal L; Gay J; Willekens C; Wemeau M; Balkaran S; Robu D; Roccaro A; Morel P; Ghobrial I; Leleu X
    Expert Opin Pharmacother; 2009 Apr; 10(5):909-16. PubMed ID: 19351237
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.