BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

106 related articles for article (PubMed ID: 1831978)

  • 1. Examination of an area in beta-hexosaminidase B homologous to that in cathepsin D linked to lysosomal targeting.
    Sagherian C; Mahuran D
    Biochem Biophys Res Commun; 1991 Aug; 179(1):477-81. PubMed ID: 1831978
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Active arginine residues in beta-hexosaminidase. Identification through studies of the B1 variant of Tay-Sachs disease.
    Brown CA; Mahuran DJ
    J Biol Chem; 1991 Aug; 266(24):15855-62. PubMed ID: 1831451
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Proteolytic processing of the pro beta chain of beta-hexosaminidase occurs at basic residues contained within an exposed disulfide loop structure.
    Sagherian C; Poroszlay S; Vavougios G; Mahuran D
    Biochem Cell Biol; 1993; 71(7-8):340-7. PubMed ID: 8123251
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Introduction of the alpha subunit mutation associated with the B1 variant of Tay-Sachs disease into the beta subunit produces a beta-hexosaminidase B without catalytic activity.
    Brown CA; Neote K; Leung A; Gravel RA; Mahuran DJ
    J Biol Chem; 1989 Dec; 264(36):21705-10. PubMed ID: 2532211
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Analysis of the glycosylation and phosphorylation of the alpha-subunit of the lysosomal enzyme, beta-hexosaminidase A, by site-directed mutagenesis.
    Weitz G; Proia RL
    J Biol Chem; 1992 May; 267(14):10039-44. PubMed ID: 1533633
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Translation initiation in the HEXB gene encoding the beta-subunit of human beta-hexosaminidase.
    Neote K; Brown CA; Mahuran DJ; Gravel RA
    J Biol Chem; 1990 Dec; 265(34):20799-806. PubMed ID: 2147427
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Identification of an active acidic residue in the catalytic site of beta-hexosaminidase.
    Tse R; Vavougios G; Hou Y; Mahuran DJ
    Biochemistry; 1996 Jun; 35(23):7599-607. PubMed ID: 8652542
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Generation of a lysosomal enzyme targeting signal in the secretory protein pepsinogen.
    Baranski TJ; Faust PL; Kornfeld S
    Cell; 1990 Oct; 63(2):281-91. PubMed ID: 2170024
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Lysine-based structure responsible for selective mannose phosphorylation of cathepsin D and cathepsin L defines a common structural motif for lysosomal enzyme targeting.
    Cuozzo JW; Tao K; Cygler M; Mort JS; Sahagian GG
    J Biol Chem; 1998 Aug; 273(33):21067-76. PubMed ID: 9694859
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Isolation and sequencing of a cDNA clone encoding rat liver lysosomal cathepsin D and the structure of three forms of mature enzymes.
    Fujita H; Tanaka Y; Noguchi Y; Kono A; Himeno M; Kato K
    Biochem Biophys Res Commun; 1991 Aug; 179(1):190-6. PubMed ID: 1883350
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Identification of the 6-sulfate binding site unique to alpha-subunit-containing isozymes of human beta-hexosaminidase.
    Sharma R; Deng H; Leung A; Mahuran D
    Biochemistry; 2001 May; 40(18):5440-6. PubMed ID: 11331008
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Beta-N-acetylhexosaminidases A and S have similar sub-cellular distributions in HL-60 cells.
    Martino S; Emiliani C; Orlacchio A; Hosseini R; Stirling JL
    Biochim Biophys Acta; 1995 Apr; 1243(3):489-95. PubMed ID: 7727524
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Identification of domains in human beta-hexosaminidase that determine substrate specificity.
    Pennybacker M; Liessem B; Moczall H; Tifft CJ; Sandhoff K; Proia RL
    J Biol Chem; 1996 Jul; 271(29):17377-82. PubMed ID: 8663217
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Two mutations produce intron insertion in mRNA and elongated beta-subunit of human beta-hexosaminidase.
    Dlott B; d'Azzo A; Quon DV; Neufeld EF
    J Biol Chem; 1990 Oct; 265(29):17921-7. PubMed ID: 2170400
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Identification of functional domains within the alpha and beta subunits of beta-hexosaminidase A through the expression of alpha-beta fusion proteins.
    Tse R; Wu YJ; Vavougios G; Hou Y; Hinek A; Mahuran DJ
    Biochemistry; 1996 Aug; 35(33):10894-903. PubMed ID: 8718882
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Characterization of the Glu and Asp residues in the active site of human beta-hexosaminidase B.
    Hou Y; Vocadlo DJ; Leung A; Withers SG; Mahuran D
    Biochemistry; 2001 Feb; 40(7):2201-9. PubMed ID: 11329289
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Intracellular targeting of lysosomal cathepsin D in COS cells.
    Takeshima H; Sakaguchi M; Mihara K; Murakami K; Omura T
    J Biochem; 1995 Nov; 118(5):981-8. PubMed ID: 8749316
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Promoters for the human beta-hexosaminidase genes, HEXA and HEXB.
    Norflus F; Yamanaka S; Proia RL
    DNA Cell Biol; 1996 Feb; 15(2):89-97. PubMed ID: 8634145
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Sequencing, expression, and enzymatic characterization of beta-hexosaminidase in rabbit lacrimal gland and primary cultured acinar cells.
    Andersson SV; Sjögren EC; Magnusson C; Gierow JP
    Glycobiology; 2005 Mar; 15(3):211-20. PubMed ID: 15483268
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Photoaffinity labeling of human lysosomal beta-hexosaminidase B. Identification of Glu-355 at the substrate binding site.
    Liessem B; Glombitza GJ; Knoll F; Lehmann J; Kellermann J; Lottspeich F; Sandhoff K
    J Biol Chem; 1995 Oct; 270(40):23693-9. PubMed ID: 7559539
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.