These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

138 related articles for article (PubMed ID: 18321713)

  • 1. Synthesis, checkpoint kinase 1 inhibitory properties and in vitro antiproliferative activities of new pyrrolocarbazoles.
    Conchon E; Anizon F; Aboab B; Golsteyn RM; Léonce S; Pfeiffer B; Prudhomme M
    Bioorg Med Chem; 2008 Apr; 16(8):4419-30. PubMed ID: 18321713
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis and biological activities of new checkpoint kinase 1 inhibitors structurally related to granulatimide.
    Conchon E; Anizon F; Aboab B; Prudhomme M
    J Med Chem; 2007 Sep; 50(19):4669-80. PubMed ID: 17722905
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis and biological activities of isogranulatimide analogues.
    Hugon B; Anizon F; Bailly C; Golsteyn RM; Pierré A; Léonce S; Hickman J; Pfeiffer B; Prudhomme M
    Bioorg Med Chem; 2007 Sep; 15(17):5965-80. PubMed ID: 17582773
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis, in vitro antiproliferative activities, and Chk1 inhibitory properties of pyrrolo[3,4-a]carbazole-1,3-diones, pyrrolo[3,4-c]carbazole-1,3-diones, and 2-aminopyridazino[3,4-a]pyrrolo[3,4-c]carbazole-1,3,4,7-tetraone.
    Conchon E; Anizon F; Aboab B; Golsteyn RM; Léonce S; Pfeiffer B; Prudhomme M
    Eur J Med Chem; 2008 Feb; 43(2):282-92. PubMed ID: 17502122
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Bis-imide granulatimide analogues as potent Checkpoint 1 kinase inhibitors.
    Hénon H; Messaoudi S; Anizon F; Aboab B; Kucharczyk N; Léonce S; Golsteyn RM; Pfeiffer B; Prudhomme M
    Eur J Pharmacol; 2007 Jan; 554(2-3):106-12. PubMed ID: 17134696
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Marine pyrrolocarbazoles and analogues: synthesis and kinase inhibition.
    Deslandes S; Chassaing S; Delfourne E
    Mar Drugs; 2009 Dec; 7(4):754-86. PubMed ID: 20098609
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis and biological activities of 7-aza rebeccamycin analogues bearing the sugar moiety on the nitrogen of the pyridine ring.
    Messaoudi S; Anizon F; Peixoto P; David-Cordonnier MH; Golsteyn RM; Léonce S; Pfeiffer B; Prudhomme M
    Bioorg Med Chem; 2006 Nov; 14(22):7551-62. PubMed ID: 16889964
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis and biological activities of 4-substituted pyrrolo[2,3-a]carbazole Pim kinase inhibitors.
    Giraud F; Akué-Gédu R; Nauton L; Candelon N; Debiton E; Théry V; Anizon F; Moreau P
    Eur J Med Chem; 2012 Oct; 56():225-36. PubMed ID: 22982527
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Pyrrolocarbazoles as checkpoint 1 kinase inhibitors.
    Hénon H; Conchon E; Hugon B; Messaoudi S; Golsteyn RM; Prudhomme M
    Anticancer Agents Med Chem; 2008 Aug; 8(6):577-97. PubMed ID: 18690823
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis and cytotoxicities of 7-aza rebeccamycin analogues bearing various substituents on the sugar moiety, on the imide nitrogen and on the carbazole framework.
    Messaoudi S; Anizon F; Léonce S; Pierré A; Pfeiffer B; Prudhomme M
    Eur J Med Chem; 2005 Oct; 40(10):961-71. PubMed ID: 15907347
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis and evaluation of 5-substituted 9-hydroxypyrrolo[3,4-c]carbazole-1,3(2H,6H)-diones as check point 1 kinase inhibitors.
    Sako Y; Ichikawa S; Osada A; Matsuda A
    Bioorg Med Chem; 2010 Nov; 18(22):7878-89. PubMed ID: 20943405
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis of C-glycosyl pyrrolo[3,4-c]carbazole-1,3(2H,6H)-diones as a scaffold for check point kinase 1 inhibitors.
    Ichikawa S; Tatebayashi N; Matsuda A
    J Org Chem; 2013 Dec; 78(23):12065-75. PubMed ID: 24127858
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis and structure-activity relationships of soluble 8-substituted 4-(2-chlorophenyl)-9-hydroxypyrrolo[3,4-c]carbazole-1,3(2H,6H)-diones as inhibitors of the Wee1 and Chk1 checkpoint kinases.
    Smaill JB; Lee HH; Palmer BD; Thompson AM; Squire CJ; Baker EN; Booth RJ; Kraker A; Hook K; Denny WA
    Bioorg Med Chem Lett; 2008 Feb; 18(3):929-33. PubMed ID: 18191399
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis and biological evaluation of new dipyrrolo[3,4-a:3,4-c]carbazole-1,3,4,6-tetraones, substituted with various saturated and unsaturated side chains via palladium catalyzed cross-coupling reactions.
    Hénon H; Anizon F; Golsteyn RM; Léonce S; Hofmann R; Pfeiffer B; Prudhomme M
    Bioorg Med Chem; 2006 Jun; 14(11):3825-34. PubMed ID: 16460946
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Rebeccamycin derivatives as dual DNA-damaging agents and potent checkpoint kinase 1 inhibitors.
    Marminon C; Anizon F; Moreau P; Pfeiffer B; Pierré A; Golsteyn RM; Peixoto P; Hildebrand MP; David-Cordonnier MH; Lozach O; Meijer L; Prudhomme M
    Mol Pharmacol; 2008 Dec; 74(6):1620-9. PubMed ID: 18768386
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Kinase inhibitory potencies and in vitro antiproliferative activities of N-10 substituted pyrrolo[2,3-a]carbazole derivatives.
    Akué-Gédu R; Letribot B; Saugues E; Debiton E; Anizon F; Moreau P
    Bioorg Med Chem Lett; 2012 Jun; 22(11):3807-9. PubMed ID: 22543026
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Identification of 1,6-dihydropyrazolo[4,3-c]carbazoles and 3,6-dihydropyrazolo[3,4-c]carbazoles as new Pim kinase inhibitors.
    Suchaud V; Gavara L; Saugues E; Nauton L; Théry V; Anizon F; Moreau P
    Bioorg Med Chem; 2013 Jul; 21(14):4102-11. PubMed ID: 23735828
    [TBL] [Abstract][Full Text] [Related]  

  • 18. New N-1,N-10-bridged pyrrolo[2,3-a]carbazole-3-carbaldehydes: synthesis and biological activities.
    Giraud F; Bourhis M; Nauton L; Théry V; Herfindal L; Døskeland SO; Anizon F; Moreau P
    Bioorg Chem; 2014 Dec; 57():108-115. PubMed ID: 25305721
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis, Pim kinase inhibitory potencies and in vitro antiproliferative activities of diversely substituted pyrrolo[2,3-a]carbazoles.
    Akué-Gédu R; Nauton L; Théry V; Bain J; Cohen P; Anizon F; Moreau P
    Bioorg Med Chem; 2010 Sep; 18(18):6865-73. PubMed ID: 20728368
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis, kinase inhibitory potencies, and in vitro antiproliferative evaluation of new Pim kinase inhibitors.
    Akué-Gédu R; Rossignol E; Azzaro S; Knapp S; Filippakopoulos P; Bullock AN; Bain J; Cohen P; Prudhomme M; Anizon F; Moreau P
    J Med Chem; 2009 Oct; 52(20):6369-81. PubMed ID: 19788246
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.