BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

643 related articles for article (PubMed ID: 18322105)

  • 1. Interplay between cyclin-dependent kinase 5 and glycogen synthase kinase 3 beta mediated by neuregulin signaling leads to differential effects on tau phosphorylation and amyloid precursor protein processing.
    Wen Y; Planel E; Herman M; Figueroa HY; Wang L; Liu L; Lau LF; Yu WH; Duff KE
    J Neurosci; 2008 Mar; 28(10):2624-32. PubMed ID: 18322105
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Suppression of cyclin-dependent kinase 5 activation by amyloid precursor protein: a novel excitoprotective mechanism involving modulation of tau phosphorylation.
    Han P; Dou F; Li F; Zhang X; Zhang YW; Zheng H; Lipton SA; Xu H; Liao FF
    J Neurosci; 2005 Dec; 25(50):11542-52. PubMed ID: 16354912
    [TBL] [Abstract][Full Text] [Related]  

  • 3. CDK5 activator protein p25 preferentially binds and activates GSK3β.
    Chow HM; Guo D; Zhou JC; Zhang GY; Li HF; Herrup K; Zhang J
    Proc Natl Acad Sci U S A; 2014 Nov; 111(45):E4887-95. PubMed ID: 25331900
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Neuroprotective effects of regulators of the glycogen synthase kinase-3beta signaling pathway in a transgenic model of Alzheimer's disease are associated with reduced amyloid precursor protein phosphorylation.
    Rockenstein E; Torrance M; Adame A; Mante M; Bar-on P; Rose JB; Crews L; Masliah E
    J Neurosci; 2007 Feb; 27(8):1981-91. PubMed ID: 17314294
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Alterations of cyclin dependent kinase 5 expression and phosphorylation in amyloid precursor protein (APP)-transfected PC12 cells.
    Czapski GA; Gąssowska M; Songin M; Radecka UD; Strosznajder JB
    FEBS Lett; 2011 Apr; 585(8):1243-8. PubMed ID: 21457712
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Valproate reduces tau phosphorylation via cyclin-dependent kinase 5 and glycogen synthase kinase 3 signaling pathways.
    Hu JP; Xie JW; Wang CY; Wang T; Wang X; Wang SL; Teng WP; Wang ZY
    Brain Res Bull; 2011 May; 85(3-4):194-200. PubMed ID: 21435383
    [TBL] [Abstract][Full Text] [Related]  

  • 7. FLZ alleviates the memory deficits in transgenic mouse model of Alzheimer's disease via decreasing beta-amyloid production and tau hyperphosphorylation.
    Bao XQ; Li N; Wang T; Kong XC; Tai WJ; Sun H; Zhang D
    PLoS One; 2013; 8(11):e78033. PubMed ID: 24223757
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Neuropathogenic role of adenylate kinase-1 in Aβ-mediated tau phosphorylation via AMPK and GSK3β.
    Park H; Kam TI; Kim Y; Choi H; Gwon Y; Kim C; Koh JY; Jung YK
    Hum Mol Genet; 2012 Jun; 21(12):2725-37. PubMed ID: 22419736
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Fuzhisan ameliorates Aβ production and tau phosphorylation in hippocampal of 11month old APP/PS1 transgenic mice: A Western blot study.
    Zhang ZX; Zhao RP; Wang DS; Wang AN
    Exp Gerontol; 2016 Nov; 84():88-95. PubMed ID: 27612601
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Cyclin-Dependent kinase 5 targeting prevents β-Amyloid aggregation involving glycogen synthase kinase 3β and phosphatases.
    Castro-Alvarez JF; Uribe-Arias A; Cardona-Gómez GP
    J Neurosci Res; 2015 Aug; 93(8):1258-66. PubMed ID: 25711385
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Activation of Cdk5/p25 and tau phosphorylation following chronic brain hypoperfusion in rats involves microRNA-195 down-regulation.
    Sun LH; Ban T; Liu CD; Chen QX; Wang X; Yan ML; Hu XL; Su XL; Bao YN; Sun LL; Zhao LJ; Pei SC; Jiang XM; Zong DK; Ai J
    J Neurochem; 2015 Sep; 134(6):1139-51. PubMed ID: 26118667
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cyclin-dependent protein kinase 5 primes microtubule-associated protein tau site-specifically for glycogen synthase kinase 3beta.
    Li T; Hawkes C; Qureshi HY; Kar S; Paudel HK
    Biochemistry; 2006 Mar; 45(10):3134-45. PubMed ID: 16519508
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Inhibition of glycogen synthase kinase-3beta downregulates total tau proteins in cultured neurons and its reversal by the blockade of protein phosphatase-2A.
    Martin L; Magnaudeix A; Esclaire F; Yardin C; Terro F
    Brain Res; 2009 Feb; 1252():66-75. PubMed ID: 19071093
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Divergent roles of GSK3 and CDK5 in APP processing.
    Ryder J; Su Y; Liu F; Li B; Zhou Y; Ni B
    Biochem Biophys Res Commun; 2003 Dec; 312(4):922-9. PubMed ID: 14651959
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Cypermethrin Stimulates GSK3β-Dependent Aβ and p-tau Proteins and Cognitive Loss in Young Rats: Reduced HB-EGF Signaling and Downstream Neuroinflammation as Critical Regulators.
    Maurya SK; Mishra J; Abbas S; Bandyopadhyay S
    Mol Neurobiol; 2016 Mar; 53(2):968-982. PubMed ID: 25575682
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Diaminothiazoles modify Tau phosphorylation and improve the tauopathy in mouse models.
    Zhang X; Hernandez I; Rei D; Mair W; Laha JK; Cornwell ME; Cuny GD; Tsai LH; Steen JA; Kosik KS
    J Biol Chem; 2013 Jul; 288(30):22042-56. PubMed ID: 23737518
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Prolyl isomerase Pin1 promotes amyloid precursor protein (APP) turnover by inhibiting glycogen synthase kinase-3β (GSK3β) activity: novel mechanism for Pin1 to protect against Alzheimer disease.
    Ma SL; Pastorino L; Zhou XZ; Lu KP
    J Biol Chem; 2012 Mar; 287(10):6969-73. PubMed ID: 22184106
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Amyloid beta-mediated cell death of cultured hippocampal neurons reveals extensive Tau fragmentation without increased full-length tau phosphorylation.
    Reifert J; Hartung-Cranston D; Feinstein SC
    J Biol Chem; 2011 Jun; 286(23):20797-811. PubMed ID: 21482827
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The spleen tyrosine kinase (Syk) regulates Alzheimer amyloid-β production and Tau hyperphosphorylation.
    Paris D; Ait-Ghezala G; Bachmeier C; Laco G; Beaulieu-Abdelahad D; Lin Y; Jin C; Crawford F; Mullan M
    J Biol Chem; 2014 Dec; 289(49):33927-44. PubMed ID: 25331948
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Abeta amyloidosis induces the initial stage of tau accumulation in APP(Sw) mice.
    Tomidokoro Y; Ishiguro K; Harigaya Y; Matsubara E; Ikeda M; Park JM; Yasutake K; Kawarabayashi T; Okamoto K; Shoji M
    Neurosci Lett; 2001 Feb; 299(3):169-72. PubMed ID: 11165762
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 33.