BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

908 related articles for article (PubMed ID: 18322257)

  • 1. In vitro validation of gamma-secretase inhibitors alone or in combination with other anti-cancer drugs for the treatment of T-cell acute lymphoblastic leukemia.
    De Keersmaecker K; Lahortiga I; Mentens N; Folens C; Van Neste L; Bekaert S; Vandenberghe P; Odero MD; Marynen P; Cools J
    Haematologica; 2008 Apr; 93(4):533-42. PubMed ID: 18322257
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Downregulation of Notch signaling by gamma-secretase inhibition can abrogate chemotherapy-induced apoptosis in T-ALL cell lines.
    Liu S; Breit S; Danckwardt S; Muckenthaler MU; Kulozik AE
    Ann Hematol; 2009 Jul; 88(7):613-21. PubMed ID: 19057901
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Gamma-secretase inhibitors suppress the growth of leukemia and lymphoma cells.
    Kogoshi H; Sato T; Koyama T; Nara N; Tohda S
    Oncol Rep; 2007 Jul; 18(1):77-80. PubMed ID: 17549349
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Apoptosis in T cell acute lymphoblastic leukemia cells after cell cycle arrest induced by pharmacological inhibition of notch signaling.
    Lewis HD; Leveridge M; Strack PR; Haldon CD; O'neil J; Kim H; Madin A; Hannam JC; Look AT; Kohl N; Draetta G; Harrison T; Kerby JA; Shearman MS; Beher D
    Chem Biol; 2007 Feb; 14(2):209-19. PubMed ID: 17317574
    [TBL] [Abstract][Full Text] [Related]  

  • 5. CUTLL1, a novel human T-cell lymphoma cell line with t(7;9) rearrangement, aberrant NOTCH1 activation and high sensitivity to gamma-secretase inhibitors.
    Palomero T; Barnes KC; Real PJ; Glade Bender JL; Sulis ML; Murty VV; Colovai AI; Balbin M; Ferrando AA
    Leukemia; 2006 Jul; 20(7):1279-87. PubMed ID: 16688224
    [TBL] [Abstract][Full Text] [Related]  

  • 6. ABL1 fusions in T-cell acute lymphoblastic leukemia.
    De Keersmaecker K
    Verh K Acad Geneeskd Belg; 2008; 70(4):245-55. PubMed ID: 19166098
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Inhibition of gamma-secretase affects proliferation of leukemia and hepatoma cell lines through Notch signaling.
    Suwanjunee S; Wongchana W; Palaga T
    Anticancer Drugs; 2008 Jun; 19(5):477-86. PubMed ID: 18418214
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Fusion of NUP214 to ABL1 on amplified episomes in T-cell acute lymphoblastic leukemia.
    Graux C; Cools J; Melotte C; Quentmeier H; Ferrando A; Levine R; Vermeesch JR; Stul M; Dutta B; Boeckx N; Bosly A; Heimann P; Uyttebroeck A; Mentens N; Somers R; MacLeod RA; Drexler HG; Look AT; Gilliland DG; Michaux L; Vandenberghe P; Wlodarska I; Marynen P; Hagemeijer A
    Nat Genet; 2004 Oct; 36(10):1084-9. PubMed ID: 15361874
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Determination of drug synergism between the tyrosine kinase inhibitors NSC 680410 (adaphostin) and/or STI571 (imatinib mesylate, Gleevec) with cytotoxic drugs against human leukemia cell lines.
    Avramis IA; Laug WE; Sausville EA; Avramis VI
    Cancer Chemother Pharmacol; 2003 Oct; 52(4):307-18. PubMed ID: 12827297
    [TBL] [Abstract][Full Text] [Related]  

  • 10. T cell acute lymphoblastic leukemia: NOTCHing the way toward a better treatment outcome.
    Pui CH
    Cancer Cell; 2009 Feb; 15(2):85-7. PubMed ID: 19185842
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Inhibition of NOTCH signaling by gamma secretase inhibitor engages the RB pathway and elicits cell cycle exit in T-cell acute lymphoblastic leukemia cells.
    Rao SS; O'Neil J; Liberator CD; Hardwick JS; Dai X; Zhang T; Tyminski E; Yuan J; Kohl NE; Richon VM; Van der Ploeg LH; Carroll PM; Draetta GF; Look AT; Strack PR; Winter CG
    Cancer Res; 2009 Apr; 69(7):3060-8. PubMed ID: 19318552
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Anti-leukemic activity of valproic acid and imatinib mesylate on human Ph+ ALL and CML cells in vitro.
    Kircher B; Schumacher P; Petzer A; Hoflehner E; Haun M; Wolf AM; Nachbaur D; Gastl G
    Eur J Haematol; 2009 Jul; 83(1):48-56. PubMed ID: 19226363
    [TBL] [Abstract][Full Text] [Related]  

  • 13. New insights into Notch1 regulation of the PI3K-AKT-mTOR1 signaling axis: targeted therapy of γ-secretase inhibitor resistant T-cell acute lymphoblastic leukemia.
    Hales EC; Taub JW; Matherly LH
    Cell Signal; 2014 Jan; 26(1):149-61. PubMed ID: 24140475
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Dual antitumor mechanisms of Notch signaling inhibitor in a T-cell acute lymphoblastic leukemia xenograft model.
    Masuda S; Kumano K; Suzuki T; Tomita T; Iwatsubo T; Natsugari H; Tojo A; Shibutani M; Mitsumori K; Hanazono Y; Ogawa S; Kurokawa M; Chiba S
    Cancer Sci; 2009 Dec; 100(12):2444-50. PubMed ID: 19775286
    [TBL] [Abstract][Full Text] [Related]  

  • 15. [Functional analysis of notch in the pathophysiology of leukemia].
    Tohda S
    Rinsho Byori; 2009 Apr; 57(4):351-6. PubMed ID: 19489437
    [TBL] [Abstract][Full Text] [Related]  

  • 16. PSEN1-selective gamma-secretase inhibition in combination with kinase or XPO-1 inhibitors effectively targets T cell acute lymphoblastic leukemia.
    Govaerts I; Prieto C; Vandersmissen C; Gielen O; Jacobs K; Provost S; Nittner D; Maertens J; Boeckx N; De Keersmaecker K; Segers H; Cools J
    J Hematol Oncol; 2021 Jun; 14(1):97. PubMed ID: 34167562
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Gamma-secretase inhibitors exerts antitumor activity via down-regulation of Notch and Nuclear factor kappa B in human tongue carcinoma cells.
    Yao J; Duan L; Fan M; Wu X
    Oral Dis; 2007 Nov; 13(6):555-63. PubMed ID: 17944672
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Therapeutic potential of Notch inhibition in T-cell acute lymphoblastic leukemia: rationale, caveats and promises.
    Sarmento LM; Barata JT
    Expert Rev Anticancer Ther; 2011 Sep; 11(9):1403-15. PubMed ID: 21929314
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Effects of human monoclonal antibody 216 on B-progenitor acute lymphoblastic leukemia in vitro.
    Bieber MM; Twist CJ; Bhat NM; Teng NN
    Pediatr Blood Cancer; 2007 Apr; 48(4):380-6. PubMed ID: 16421902
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Notch1 regulates chemotaxis and proliferation by controlling the CC-chemokine receptors 5 and 9 in T cell acute lymphoblastic leukaemia.
    Mirandola L; Chiriva-Internati M; Montagna D; Locatelli F; Zecca M; Ranzani M; Basile A; Locati M; Cobos E; Kast WM; Asselta R; Paraboschi EM; Comi P; Chiaramonte R
    J Pathol; 2012 Apr; 226(5):713-22. PubMed ID: 21984373
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 46.