234 related articles for article (PubMed ID: 18324787)
1. Cross-linking of the DNA repair protein Omicron6-alkylguanine DNA alkyltransferase to DNA in the presence of antitumor nitrogen mustards.
Loeber R; Michaelson E; Fang Q; Campbell C; Pegg AE; Tretyakova N
Chem Res Toxicol; 2008 Apr; 21(4):787-95. PubMed ID: 18324787
[TBL] [Abstract][Full Text] [Related]
2. Cross-linking of the human DNA repair protein O6-alkylguanine DNA alkyltransferase to DNA in the presence of 1,2,3,4-diepoxybutane.
Loeber R; Rajesh M; Fang Q; Pegg AE; Tretyakova N
Chem Res Toxicol; 2006 May; 19(5):645-54. PubMed ID: 16696566
[TBL] [Abstract][Full Text] [Related]
3. Proteomic analysis of DNA-protein cross-linking by antitumor nitrogen mustards.
Loeber RL; Michaelson-Richie ED; Codreanu SG; Liebler DC; Campbell CR; Tretyakova NY
Chem Res Toxicol; 2009 Jun; 22(6):1151-62. PubMed ID: 19480393
[TBL] [Abstract][Full Text] [Related]
4. Cross-linking of the DNA repair protein O
Ming X; Michaelson-Richie ED; Groehler AS; Villalta PW; Campbell C; Tretyakova NY
DNA Repair (Amst); 2020 May; 89():102840. PubMed ID: 32283495
[TBL] [Abstract][Full Text] [Related]
5. Adenine-containing DNA-DNA cross-links of antitumor nitrogen mustards.
Balcome S; Park S; Quirk Dorr DR; Hafner L; Phillips L; Tretyakova N
Chem Res Toxicol; 2004 Jul; 17(7):950-62. PubMed ID: 15257621
[TBL] [Abstract][Full Text] [Related]
6. Mass spectrometry based approach to study the kinetics of O6-alkylguanine DNA alkyltransferase-mediated repair of O6-pyridyloxobutyl-2'-deoxyguanosine adducts in DNA.
Kotandeniya D; Murphy D; Seneviratne U; Guza R; Pegg A; Kanugula S; Tretyakova N
Chem Res Toxicol; 2011 Nov; 24(11):1966-75. PubMed ID: 21913712
[TBL] [Abstract][Full Text] [Related]
7. Measurement of O(6)-alkylguanine-DNA alkyltransferase activity in tumour cells using stable isotope dilution HPLC-ESI-MS/MS.
Sun G; Zhao L; Fan T; Ren T; Zhong R
J Chromatogr B Analyt Technol Biomed Life Sci; 2016 Oct; 1033-1034():138-146. PubMed ID: 27544051
[TBL] [Abstract][Full Text] [Related]
8. Synthesis and antitumor activity evaluation of a novel combi-nitrosourea prodrug: Designed to release a DNA cross-linking agent and an inhibitor of O(6)-alkylguanine-DNA alkyltransferase.
Sun G; Zhang N; Zhao L; Fan T; Zhang S; Zhong R
Bioorg Med Chem; 2016 May; 24(9):2097-107. PubMed ID: 27041398
[TBL] [Abstract][Full Text] [Related]
9. Covalent DNA-Protein Cross-Linking by Phosphoramide Mustard and Nornitrogen Mustard in Human Cells.
Groehler A; Villalta PW; Campbell C; Tretyakova N
Chem Res Toxicol; 2016 Feb; 29(2):190-202. PubMed ID: 26692166
[TBL] [Abstract][Full Text] [Related]
10. Effect of O6-benzylguanine on nitrogen mustard-induced toxicity, apoptosis, and mutagenicity in Chinese hamster ovary cells.
Cai Y; Ludeman SM; Wilson LR; Chung AB; Dolan ME
Mol Cancer Ther; 2001 Nov; 1(1):21-8. PubMed ID: 12467235
[TBL] [Abstract][Full Text] [Related]
11. Mechlorethamine-induced DNA-protein cross-linking in human fibrosarcoma (HT1080) cells.
Michaelson-Richie ED; Ming X; Codreanu SG; Loeber RL; Liebler DC; Campbell C; Tretyakova NY
J Proteome Res; 2011 Jun; 10(6):2785-96. PubMed ID: 21486066
[TBL] [Abstract][Full Text] [Related]
12. O6-alkylguanine-DNA alkyltransferase has opposing effects in modulating the genotoxicity of dibromomethane and bromomethyl acetate.
Liu L; Williams KM; Guengerich FP; Pegg AE
Chem Res Toxicol; 2004 Jun; 17(6):742-52. PubMed ID: 15206895
[TBL] [Abstract][Full Text] [Related]
13. Kinetics of O(6)-pyridyloxobutyl-2'-deoxyguanosine repair by human O(6)-alkylguanine DNA alkyltransferase.
Kotandeniya D; Murphy D; Yan S; Park S; Seneviratne U; Koopmeiners JS; Pegg A; Kanugula S; Kassie F; Tretyakova N
Biochemistry; 2013 Jun; 52(23):4075-88. PubMed ID: 23683164
[TBL] [Abstract][Full Text] [Related]
14. Kinetics of O(6)-methyl-2'-deoxyguanosine repair by O(6)-alkylguanine DNA alkyltransferase within K-ras gene-derived DNA sequences.
Guza R; Rajesh M; Fang Q; Pegg AE; Tretyakova N
Chem Res Toxicol; 2006 Apr; 19(4):531-8. PubMed ID: 16608164
[TBL] [Abstract][Full Text] [Related]
15. Effect of alterations of key active site residues in O6-alkylguanine-DNA Alkyltransferase on its ability to modulate the genotoxicity of 1,2-dibromoethane.
Liu L; Watanabe K; Fang Q; Williams KM; Guengerich FP; Pegg AE
Chem Res Toxicol; 2007 Jan; 20(1):155-63. PubMed ID: 17226938
[TBL] [Abstract][Full Text] [Related]
16. A New Cross-Link for an Old Cross-Linking Drug: The Nitrogen Mustard Anticancer Agent Mechlorethamine Generates Cross-Links Derived from Abasic Sites in Addition to the Expected Drug-Bridged Cross-Links.
Nejad MI; Johnson KM; Price NE; Gates KS
Biochemistry; 2016 Dec; 55(50):7033-7041. PubMed ID: 27992994
[TBL] [Abstract][Full Text] [Related]
17. DNA sequence selectivity of guanine-N7 alkylation by nitrogen mustards.
Mattes WB; Hartley JA; Kohn KW
Nucleic Acids Res; 1986 Apr; 14(7):2971-87. PubMed ID: 3960738
[TBL] [Abstract][Full Text] [Related]
18. Expression of the inactive C145A mutant human O6-alkylguanine-DNA alkyltransferase in E.coli increases cell killing and mutations by N-methyl-N'-nitro-N-nitrosoguanidine.
Edara S; Kanugula S; Pegg AE
Carcinogenesis; 1999 Jan; 20(1):103-8. PubMed ID: 9934856
[TBL] [Abstract][Full Text] [Related]
19. Paradoxical enhancement of the toxicity of 1,2-dibromoethane by O6-alkylguanine-DNA alkyltransferase.
Liu L; Pegg AE; Williams KM; Guengerich FP
J Biol Chem; 2002 Oct; 277(40):37920-8. PubMed ID: 12151404
[TBL] [Abstract][Full Text] [Related]
20. Conserved residue lysine165 is essential for the ability of O6-alkylguanine-DNA alkyltransferase to react with O6-benzylguanine.
Xu-Welliver M; Kanugula S; Loktionova NA; Crone TM; Pegg AE
Biochem J; 2000 Apr; 347(Pt 2):527-34. PubMed ID: 10749683
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]