BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

245 related articles for article (PubMed ID: 18332083)

  • 1. ATF5 is a highly abundant liver-enriched transcription factor that cooperates with constitutive androstane receptor in the transactivation of CYP2B6: implications in hepatic stress responses.
    Pascual M; Gómez-Lechón MJ; Castell JV; Jover R
    Drug Metab Dispos; 2008 Jun; 36(6):1063-72. PubMed ID: 18332083
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Fasting induced up-regulation of activating transcription factor 5 in mouse liver.
    Shimizu YI; Morita M; Ohmi A; Aoyagi S; Ebihara H; Tonaki D; Horino Y; Iijima M; Hirose H; Takahashi S; Takahashi Y
    Life Sci; 2009 Jun; 84(25-26):894-902. PubMed ID: 19376136
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Cigarette smoke extract induces CYP2B6 through constitutive androstane receptor in hepatocytes.
    Washio I; Maeda M; Sugiura C; Shiga R; Yoshida M; Nonen S; Fujio Y; Azuma J
    Drug Metab Dispos; 2011 Jan; 39(1):1-3. PubMed ID: 20966044
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Dexamethasone enhances constitutive androstane receptor expression in human hepatocytes: consequences on cytochrome P450 gene regulation.
    Pascussi JM; Gerbal-Chaloin S; Fabre JM; Maurel P; Vilarem MJ
    Mol Pharmacol; 2000 Dec; 58(6):1441-50. PubMed ID: 11093784
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A novel distal enhancer module regulated by pregnane X receptor/constitutive androstane receptor is essential for the maximal induction of CYP2B6 gene expression.
    Wang H; Faucette S; Sueyoshi T; Moore R; Ferguson S; Negishi M; LeCluyse EL
    J Biol Chem; 2003 Apr; 278(16):14146-52. PubMed ID: 12571232
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Regulation of cytochrome P450 2C9 expression in primary cultures of human hepatocytes.
    Sahi J; Shord SS; Lindley C; Ferguson S; LeCluyse EL
    J Biochem Mol Toxicol; 2009; 23(1):43-58. PubMed ID: 19202563
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Regulation of the human CYP2B6 gene by the nuclear pregnane X receptor.
    Goodwin B; Moore LB; Stoltz CM; McKee DD; Kliewer SA
    Mol Pharmacol; 2001 Sep; 60(3):427-31. PubMed ID: 11502872
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Constitutive androstane receptor and pregnane X receptor gene expression in human liver: interindividual variability and correlation with CYP2B6 mRNA levels.
    Chang TK; Bandiera SM; Chen J
    Drug Metab Dispos; 2003 Jan; 31(1):7-10. PubMed ID: 12485946
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Retinoid X receptor-alpha-dependent transactivation by a naturally occurring structural variant of human constitutive androstane receptor (NR1I3).
    Auerbach SS; Stoner MA; Su S; Omiecinski CJ
    Mol Pharmacol; 2005 Nov; 68(5):1239-53. PubMed ID: 16099843
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Regulation of the human CHOP gene promoter by the stress response transcription factor ATF5 via the AARE1 site in human hepatoma HepG2 cells.
    Yamazaki T; Ohmi A; Kurumaya H; Kato K; Abe T; Yamamoto H; Nakanishi N; Okuyama R; Umemura M; Kaise T; Watanabe R; Okawa Y; Takahashi S; Takahashi Y
    Life Sci; 2010 Aug; 87(9-10):294-301. PubMed ID: 20654631
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Comparison of immortalized Fa2N-4 cells and human hepatocytes as in vitro models for cytochrome P450 induction.
    Hariparsad N; Carr BA; Evers R; Chu X
    Drug Metab Dispos; 2008 Jun; 36(6):1046-55. PubMed ID: 18332078
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Human constitutive androstane receptor mediates induction of CYP2B6 gene expression by phenytoin.
    Wang H; Faucette S; Moore R; Sueyoshi T; Negishi M; LeCluyse E
    J Biol Chem; 2004 Jul; 279(28):29295-301. PubMed ID: 15123723
    [TBL] [Abstract][Full Text] [Related]  

  • 13. CCAAT/enhancer-binding protein alpha (C/EBPalpha) and hepatocyte nuclear factor 4alpha (HNF4alpha) synergistically cooperate with constitutive androstane receptor to transactivate the human cytochrome P450 2B6 (CYP2B6) gene: application to the development of a metabolically competent human hepatic cell model.
    Benet M; Lahoz A; Guzmán C; Castell JV; Jover R
    J Biol Chem; 2010 Sep; 285(37):28457-71. PubMed ID: 20622021
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Characterization of activating signal cointegrator-2 as a novel transcriptional coactivator of the xenobiotic nuclear receptor constitutive androstane receptor.
    Choi E; Lee S; Yeom SY; Kim GH; Lee JW; Kim SW
    Mol Endocrinol; 2005 Jul; 19(7):1711-9. PubMed ID: 15764585
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Glucocorticoid receptor enhancement of pregnane X receptor-mediated CYP2B6 regulation in primary human hepatocytes.
    Wang H; Faucette SR; Gilbert D; Jolley SL; Sueyoshi T; Negishi M; LeCluyse EL
    Drug Metab Dispos; 2003 May; 31(5):620-30. PubMed ID: 12695351
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The orphan nuclear receptor DAX-1 functions as a potent corepressor of the constitutive androstane receptor (NR1I3).
    Laurenzana EM; Chen T; Kannuswamy M; Sell BE; Strom SC; Li Y; Omiecinski CJ
    Mol Pharmacol; 2012 Nov; 82(5):918-28. PubMed ID: 22896671
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Constitutive androstane receptor (CAR) as a potential sensing biomarker of persistent organic pollutants (POPs) in aquatic mammal: molecular characterization, expression level, and ligand profiling in Baikal seal (Pusa sibirica).
    Sakai H; Iwata H; Kim EY; Tsydenova O; Miyazaki N; Petrov EA; Batoev VB; Tanabe S
    Toxicol Sci; 2006 Nov; 94(1):57-70. PubMed ID: 16929008
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Induction of drug-metabolizing enzymes by garlic and allyl sulfide compounds via activation of constitutive androstane receptor and nuclear factor E2-related factor 2.
    Fisher CD; Augustine LM; Maher JM; Nelson DM; Slitt AL; Klaassen CD; Lehman-McKeeman LD; Cherrington NJ
    Drug Metab Dispos; 2007 Jun; 35(6):995-1000. PubMed ID: 17353348
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Involvement of pregnane X receptor in the regulation of CYP2B6 gene expression by oltipraz in human hepatocytes.
    Piton A; Rauch C; Langouet S; Guillouzo A; Morel F
    Toxicol In Vitro; 2010 Mar; 24(2):452-9. PubMed ID: 19833192
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Hepatic expression of thyroid hormone-responsive spot 14 protein is regulated by constitutive androstane receptor (NR1I3).
    Breuker C; Moreau A; Lakhal L; Tamasi V; Parmentier Y; Meyer U; Maurel P; Lumbroso S; Vilarem MJ; Pascussi JM
    Endocrinology; 2010 Apr; 151(4):1653-61. PubMed ID: 20185760
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.