549 related articles for article (PubMed ID: 18332086)
1. Intestinal human colon adenocarcinoma cell line LS180 is an excellent model to study pregnane X receptor, but not constitutive androstane receptor, mediated CYP3A4 and multidrug resistance transporter 1 induction: studies with anti-human immunodeficiency virus protease inhibitors.
Gupta A; Mugundu GM; Desai PB; Thummel KE; Unadkat JD
Drug Metab Dispos; 2008 Jun; 36(6):1172-80. PubMed ID: 18332086
[TBL] [Abstract][Full Text] [Related]
2. Fucoxanthin attenuates rifampin-induced cytochrome P450 3A4 (CYP3A4) and multiple drug resistance 1 (MDR1) gene expression through pregnane X receptor (PXR)-mediated pathways in human hepatoma HepG2 and colon adenocarcinoma LS174T cells.
Liu CL; Lim YP; Hu ML
Mar Drugs; 2012 Jan; 10(1):242-257. PubMed ID: 22363234
[TBL] [Abstract][Full Text] [Related]
3. Valproic acid induces CYP3A4 and MDR1 gene expression by activation of constitutive androstane receptor and pregnane X receptor pathways.
Cerveny L; Svecova L; Anzenbacherova E; Vrzal R; Staud F; Dvorak Z; Ulrichova J; Anzenbacher P; Pavek P
Drug Metab Dispos; 2007 Jul; 35(7):1032-41. PubMed ID: 17392393
[TBL] [Abstract][Full Text] [Related]
4. Induction of CYP3A4 and MDR1 gene expression by baicalin, baicalein, chlorogenic acid, and ginsenoside Rf through constitutive androstane receptor- and pregnane X receptor-mediated pathways.
Li Y; Wang Q; Yao X; Li Y
Eur J Pharmacol; 2010 Aug; 640(1-3):46-54. PubMed ID: 20580705
[TBL] [Abstract][Full Text] [Related]
5. Activation of pregnane X receptor and induction of MDR1 by dietary phytochemicals.
Satsu H; Hiura Y; Mochizuki K; Hamada M; Shimizu M
J Agric Food Chem; 2008 Jul; 56(13):5366-73. PubMed ID: 18540626
[TBL] [Abstract][Full Text] [Related]
6. A human immunodeficiency virus protease inhibitor is a novel functional inhibitor of human pregnane X receptor.
Healan-Greenberg C; Waring JF; Kempf DJ; Blomme EA; Tirona RG; Kim RB
Drug Metab Dispos; 2008 Mar; 36(3):500-7. PubMed ID: 18096673
[TBL] [Abstract][Full Text] [Related]
7. Transport of 5,5-diphenylbarbituric acid and its precursors and their effect on P-gp, MRP2 and CYP3A4 in Caco-2 and LS180 cells.
Fan J; Maeng HJ; Du Y; Kwan D; Pang KS
Eur J Pharm Sci; 2011 Jan; 42(1-2):19-29. PubMed ID: 20955791
[TBL] [Abstract][Full Text] [Related]
8. Bioactive terpenoids and flavonoids from Ginkgo biloba extract induce the expression of hepatic drug-metabolizing enzymes through pregnane X receptor, constitutive androstane receptor, and aryl hydrocarbon receptor-mediated pathways.
Li L; Stanton JD; Tolson AH; Luo Y; Wang H
Pharm Res; 2009 Apr; 26(4):872-82. PubMed ID: 19034627
[TBL] [Abstract][Full Text] [Related]
9. The pregnane X receptor regulates gene expression in a ligand- and promoter-selective fashion.
Masuyama H; Suwaki N; Tateishi Y; Nakatsukasa H; Segawa T; Hiramatsu Y
Mol Endocrinol; 2005 May; 19(5):1170-80. PubMed ID: 15650019
[TBL] [Abstract][Full Text] [Related]
10. Gene expression of CYP3A4, ABC-transporters (MDR1 and MRP1-MRP5) and hPXR in three different human colon carcinoma cell lines.
Pfrunder A; Gutmann H; Beglinger C; Drewe J
J Pharm Pharmacol; 2003 Jan; 55(1):59-66. PubMed ID: 12625868
[TBL] [Abstract][Full Text] [Related]
11. The pregnane X receptor binds to response elements in a genomic context-dependent manner, and PXR activator rifampicin selectively alters the binding among target genes.
Song X; Xie M; Zhang H; Li Y; Sachdeva K; Yan B
Drug Metab Dispos; 2004 Jan; 32(1):35-42. PubMed ID: 14709618
[TBL] [Abstract][Full Text] [Related]
12. Gancao (Glycyrrhizae Radix) provides the main contribution to Shaoyao-Gancao decoction on enhancements of CYP3A4 and MDR1 expression via pregnane X receptor pathway in vitro.
Feng D; Tang T; Fan R; Luo J; Cui H; Wang Y; Gan P
BMC Complement Altern Med; 2018 Dec; 18(1):345. PubMed ID: 30594244
[TBL] [Abstract][Full Text] [Related]
13. Modulation of pregnane X receptor (PXR) and constitutive androstane receptor (CAR) activation by ursolic acid (UA) attenuates rifampin-isoniazid cytotoxicity.
Chang HY; Chen CJ; Ma WC; Cheng WK; Lin YN; Lee YR; Chen JJ; Lim YP
Phytomedicine; 2017 Dec; 36():37-49. PubMed ID: 29157826
[TBL] [Abstract][Full Text] [Related]
14. Diindolylmethane, a naturally occurring compound, induces CYP3A4 and MDR1 gene expression by activating human PXR.
Pondugula SR; Flannery PC; Abbott KL; Coleman ES; Mani S; Samuel T; Xie W
Toxicol Lett; 2015 Feb; 232(3):580-9. PubMed ID: 25542144
[TBL] [Abstract][Full Text] [Related]
15. Influence of sildenafil and tadalafil on the enzyme- and transporter-inducing effects of bosentan and ambrisentan in LS180 cells.
Weiss J; Theile D; Spalwisz A; Burhenne J; Riedel KD; Haefeli WE
Biochem Pharmacol; 2013 Jan; 85(2):265-73. PubMed ID: 23219525
[TBL] [Abstract][Full Text] [Related]
16. PXR-mediated transcriptional activation of CYP3A4 by cryptotanshinone and tanshinone IIA.
Yu C; Ye S; Sun H; Liu Y; Gao L; Shen C; Chen S; Zeng S
Chem Biol Interact; 2009 Jan; 177(1):58-64. PubMed ID: 18805405
[TBL] [Abstract][Full Text] [Related]
17. Endosulfan induces CYP2B6 and CYP3A4 by activating the pregnane X receptor.
Casabar RC; Das PC; Dekrey GK; Gardiner CS; Cao Y; Rose RL; Wallace AD
Toxicol Appl Pharmacol; 2010 Jun; 245(3):335-43. PubMed ID: 20361990
[TBL] [Abstract][Full Text] [Related]
18. Antimalarial artemisinin drugs induce cytochrome P450 and MDR1 expression by activation of xenosensors pregnane X receptor and constitutive androstane receptor.
Burk O; Arnold KA; Nussler AK; Schaeffeler E; Efimova E; Avery BA; Avery MA; Fromm MF; Eichelbaum M
Mol Pharmacol; 2005 Jun; 67(6):1954-65. PubMed ID: 15761118
[TBL] [Abstract][Full Text] [Related]
19. The effects of splicing variant of PXR PAR-2 on CYP3A4 and MDR1 mRNA expressions.
Liu Y; Ji W; Yin Y; Fan L; Zhang J; Yun H; Wang N; Li Q; Wei Z; Ouyang D; Zhou HH
Clin Chim Acta; 2009 May; 403(1-2):142-4. PubMed ID: 19232333
[TBL] [Abstract][Full Text] [Related]
20. Glucocorticoid-mediated induction of CYP3A4 is decreased by disruption of a protein: DNA interaction distinct from the pregnane X receptor response element.
El-Sankary W; Bombail V; Gibson GG; Plant N
Drug Metab Dispos; 2002 Sep; 30(9):1029-34. PubMed ID: 12167569
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
