229 related articles for article (PubMed ID: 18332218)
1. Essential role of B-Raf in oligodendrocyte maturation and myelination during postnatal central nervous system development.
Galabova-Kovacs G; Catalanotti F; Matzen D; Reyes GX; Zezula J; Herbst R; Silva A; Walter I; Baccarini M
J Cell Biol; 2008 Mar; 180(5):947-55. PubMed ID: 18332218
[TBL] [Abstract][Full Text] [Related]
2. Enhanced inhibition of ERK signaling by a novel allosteric MEK inhibitor, CH5126766, that suppresses feedback reactivation of RAF activity.
Ishii N; Harada N; Joseph EW; Ohara K; Miura T; Sakamoto H; Matsuda Y; Tomii Y; Tachibana-Kondo Y; Iikura H; Aoki T; Shimma N; Arisawa M; Sowa Y; Poulikakos PI; Rosen N; Aoki Y; Sakai T
Cancer Res; 2013 Jul; 73(13):4050-4060. PubMed ID: 23667175
[TBL] [Abstract][Full Text] [Related]
3. The tumour suppressor DiRas3 interacts with C-RAF and downregulates MEK activity to restrict cell migration.
Klingauf M; Beck M; Berge U; Turgay Y; Heinzer S; Horvath P; Kroschewski R
Biol Cell; 2013 Feb; 105(2):91-107. PubMed ID: 23157514
[TBL] [Abstract][Full Text] [Related]
4. G protein-coupled receptor 37 is a negative regulator of oligodendrocyte differentiation and myelination.
Yang HJ; Vainshtein A; Maik-Rachline G; Peles E
Nat Commun; 2016 Mar; 7():10884. PubMed ID: 26961174
[TBL] [Abstract][Full Text] [Related]
5. Different effects of point mutations within the B-Raf glycine-rich loop in colorectal tumors on mitogen-activated protein/extracellular signal-regulated kinase kinase/extracellular signal-regulated kinase and nuclear factor kappaB pathway and cellular transformation.
Ikenoue T; Hikiba Y; Kanai F; Aragaki J; Tanaka Y; Imamura J; Imamura T; Ohta M; Ijichi H; Tateishi K; Kawakami T; Matsumura M; Kawabe T; Omata M
Cancer Res; 2004 May; 64(10):3428-35. PubMed ID: 15150094
[TBL] [Abstract][Full Text] [Related]
6. Mechanism of activation of the RAF-ERK signaling pathway by oncogenic mutations of B-RAF.
Wan PT; Garnett MJ; Roe SM; Lee S; Niculescu-Duvaz D; Good VM; Jones CM; Marshall CJ; Springer CJ; Barford D; Marais R;
Cell; 2004 Mar; 116(6):855-67. PubMed ID: 15035987
[TBL] [Abstract][Full Text] [Related]
7. Regulation and role of Raf-1/B-Raf heterodimerization.
Rushworth LK; Hindley AD; O'Neill E; Kolch W
Mol Cell Biol; 2006 Mar; 26(6):2262-72. PubMed ID: 16508002
[TBL] [Abstract][Full Text] [Related]
8. Protein kinase C alpha trigger Ras and Raf-independent MEK/ERK activation for TPA-induced growth inhibition of human hepatoma cell HepG2.
Wen-Sheng W
Cancer Lett; 2006 Jul; 239(1):27-35. PubMed ID: 16169661
[TBL] [Abstract][Full Text] [Related]
9. A Raf-induced allosteric transition of KSR stimulates phosphorylation of MEK.
Brennan DF; Dar AC; Hertz NT; Chao WC; Burlingame AL; Shokat KM; Barford D
Nature; 2011 Apr; 472(7343):366-9. PubMed ID: 21441910
[TBL] [Abstract][Full Text] [Related]
10. Ras-mutant cancer cells display B-Raf binding to Ras that activates extracellular signal-regulated kinase and is inhibited by protein kinase A phosphorylation.
Li Y; Takahashi M; Stork PJS
J Biol Chem; 2013 Sep; 288(38):27646-27657. PubMed ID: 23893412
[TBL] [Abstract][Full Text] [Related]
11. MEK-1 activates C-Raf through a Ras-independent mechanism.
Leicht DT; Balan V; Zhu J; Kaplun A; Bronisz A; Rana A; Tzivion G
Biochim Biophys Acta; 2013 May; 1833(5):976-86. PubMed ID: 23360980
[TBL] [Abstract][Full Text] [Related]
12. Rit contributes to nerve growth factor-induced neuronal differentiation via activation of B-Raf-extracellular signal-regulated kinase and p38 mitogen-activated protein kinase cascades.
Shi GX; Andres DA
Mol Cell Biol; 2005 Jan; 25(2):830-46. PubMed ID: 15632082
[TBL] [Abstract][Full Text] [Related]
13. Cyclic AMP signaling reduces sirtuin 6 expression in non-small cell lung cancer cells by promoting ubiquitin-proteasomal degradation via inhibition of the Raf-MEK-ERK (Raf/mitogen-activated extracellular signal-regulated kinase/extracellular signal-regulated kinase) pathway.
Kim EJ; Juhnn YS
J Biol Chem; 2015 Apr; 290(15):9604-13. PubMed ID: 25713071
[TBL] [Abstract][Full Text] [Related]
14. RAF inhibitors prime wild-type RAF to activate the MAPK pathway and enhance growth.
Hatzivassiliou G; Song K; Yen I; Brandhuber BJ; Anderson DJ; Alvarado R; Ludlam MJ; Stokoe D; Gloor SL; Vigers G; Morales T; Aliagas I; Liu B; Sideris S; Hoeflich KP; Jaiswal BS; Seshagiri S; Koeppen H; Belvin M; Friedman LS; Malek S
Nature; 2010 Mar; 464(7287):431-5. PubMed ID: 20130576
[TBL] [Abstract][Full Text] [Related]
15. Interferon-alpha2b reduces phosphorylation and activity of MEK and ERK through a Ras/Raf-independent mechanism.
Romerio F; Riva A; Zella D
Br J Cancer; 2000 Aug; 83(4):532-8. PubMed ID: 10945503
[TBL] [Abstract][Full Text] [Related]
16. LINGO-1 negatively regulates myelination by oligodendrocytes.
Mi S; Miller RH; Lee X; Scott ML; Shulag-Morskaya S; Shao Z; Chang J; Thill G; Levesque M; Zhang M; Hession C; Sah D; Trapp B; He Z; Jung V; McCoy JM; Pepinsky RB
Nat Neurosci; 2005 Jun; 8(6):745-51. PubMed ID: 15895088
[TBL] [Abstract][Full Text] [Related]
17. Antitumor efficacy of the novel RAF inhibitor GDC-0879 is predicted by BRAFV600E mutational status and sustained extracellular signal-regulated kinase/mitogen-activated protein kinase pathway suppression.
Hoeflich KP; Herter S; Tien J; Wong L; Berry L; Chan J; O'Brien C; Modrusan Z; Seshagiri S; Lackner M; Stern H; Choo E; Murray L; Friedman LS; Belvin M
Cancer Res; 2009 Apr; 69(7):3042-51. PubMed ID: 19276360
[TBL] [Abstract][Full Text] [Related]
18. MEK-independent survival of B-RAFV600E melanoma cells selected for resistance to apoptosis induced by the RAF inhibitor PLX4720.
Jiang CC; Lai F; Thorne RF; Yang F; Liu H; Hersey P; Zhang XD
Clin Cancer Res; 2011 Feb; 17(4):721-30. PubMed ID: 21088259
[TBL] [Abstract][Full Text] [Related]
19. Induction of beta3-integrin gene expression by sustained activation of the Ras-regulated Raf-MEK-extracellular signal-regulated kinase signaling pathway.
Woods D; Cherwinski H; Venetsanakos E; Bhat A; Gysin S; Humbert M; Bray PF; Saylor VL; McMahon M
Mol Cell Biol; 2001 May; 21(9):3192-205. PubMed ID: 11287623
[TBL] [Abstract][Full Text] [Related]
20. Protein Kinase CK2α Maintains Extracellular Signal-regulated Kinase (ERK) Activity in a CK2α Kinase-independent Manner to Promote Resistance to Inhibitors of RAF and MEK but Not ERK in BRAF Mutant Melanoma.
Zhou B; Ritt DA; Morrison DK; Der CJ; Cox AD
J Biol Chem; 2016 Aug; 291(34):17804-15. PubMed ID: 27226552
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
