BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

151 related articles for article (PubMed ID: 18336347)

  • 21. Total synthesis and biological evaluation of potent analogues of dictyostatin: modification of the C2-C6 dienoate region.
    Paterson I; Gardner NM; Guzmán E; Wright AE
    Bioorg Med Chem Lett; 2008 Dec; 18(23):6268-72. PubMed ID: 18951787
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Designer discodermolide segments via ozonolysis of vinyl phosphonates.
    Mollat du Jourdin X; Noshi M; Fuchs PL
    Org Lett; 2009 Feb; 11(3):543-6. PubMed ID: 19117490
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Design and synthesis of (+)-discodermolide-paclitaxel hybrids leading to enhanced biological activity.
    Smith AB; Sugasawa K; Atasoylu O; Yang CP; Horwitz SB
    J Med Chem; 2011 Sep; 54(18):6319-27. PubMed ID: 21870795
    [TBL] [Abstract][Full Text] [Related]  

  • 24. A photoaffinity analogue of discodermolide specifically labels a peptide in beta-tubulin.
    Xia S; Kenesky CS; Rucker PV; Smith AB; Orr GA; Horwitz SB
    Biochemistry; 2006 Oct; 45(39):11762-75. PubMed ID: 17002277
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Synthesis and biological assessment of simplified analogues of the potent microtubule stabilizer (+)-discodermolide.
    Mínguez JM; Kim SY; Giuliano KA; Balachandran R; Madiraju C; Day BW; Curran DP
    Bioorg Med Chem; 2003 Jul; 11(15):3335-57. PubMed ID: 12837544
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Distinct pose of discodermolide in taxol binding pocket drives a complementary mode of microtubule stabilization.
    Khrapunovich-Baine M; Menon V; Verdier-Pinard P; Smith AB; Angeletti RH; Fiser A; Horwitz SB; Xiao H
    Biochemistry; 2009 Dec; 48(49):11664-77. PubMed ID: 19863156
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Design, synthesis and biological evaluation of a simplified fluorescently labeled discodermolide as a molecular probe to study the binding of discodermolide to tubulin.
    Qi J; Blanden AR; Bane S; Kingston DG
    Bioorg Med Chem; 2011 Sep; 19(17):5247-54. PubMed ID: 21802957
    [TBL] [Abstract][Full Text] [Related]  

  • 28. The discodermolide hairpin structure flows from conformationally stable modular motifs.
    Jogalekar AS; Kriel FH; Shi Q; Cornett B; Cicero D; Snyder JP
    J Med Chem; 2010 Jan; 53(1):155-65. PubMed ID: 19894728
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Discodermolide analogues as the chemical component of combination bacteriolytic therapy.
    Smith AB; Freeze BS; LaMarche MJ; Sager J; Kinzler KW; Vogelstein B
    Bioorg Med Chem Lett; 2005 Aug; 15(15):3623-6. PubMed ID: 15979874
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Total synthesis of (+)-discodermolide: an improved endgame exploiting a Still-Gennari-type olefination with a C1-C8 beta-ketophosphonate fragment.
    Paterson I; Lyothier I
    Org Lett; 2004 Dec; 6(26):4933-6. PubMed ID: 15606103
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Scalable, catalytic asymmetric synthesis of syn, anti stereotriad building blocks for polypropionate antibiotics.
    Parker KA; Cao H
    Org Lett; 2006 Aug; 8(16):3541-4. PubMed ID: 16869655
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Toward a commercial synthesis of (+)-discodermolide.
    Mickel SJ
    Curr Opin Drug Discov Devel; 2004 Nov; 7(6):869-81. PubMed ID: 15595446
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Iron complexation to oxygen rich marine natural products: a computational study.
    Manning TJ; Williams J; Jarrard J; Gorman T
    Mar Drugs; 2010 Jan; 8(1):1-23. PubMed ID: 20161968
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Design, synthesis, and evaluation of analogues of (+)-14-normethyldiscodermolide.
    Smith AB; Freeze BS; Lamarche MJ; Hirose T; Brouard I; Xian M; Sundermann KF; Shaw SJ; Burlingame MA; Horwitz SB; Myles DC
    Org Lett; 2005 Jan; 7(2):315-8. PubMed ID: 15646986
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Decarboxylative Grob-type fragmentations in the synthesis of trisubstituted Z olefins: application to peloruside A, discodermolide, and epothilone D.
    Prantz K; Mulzer J
    Angew Chem Int Ed Engl; 2009; 48(27):5030-3. PubMed ID: 19492384
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Design, synthesis and biological evaluation of a macrocyclic discodermolide/dictyostatin hybrid.
    Paterson I; Gardner NM
    Chem Commun (Camb); 2007 Jan; (1):49-51. PubMed ID: 17279257
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Insights into the interaction of discodermolide and docetaxel with tubulin. Mapping the binding sites of microtubule-stabilizing agents by using an integrated NMR and computational approach.
    Canales A; Rodríguez-Salarichs J; Trigili C; Nieto L; Coderch C; Andreu JM; Paterson I; Jiménez-Barbero J; Díaz JF
    ACS Chem Biol; 2011 Aug; 6(8):789-99. PubMed ID: 21539341
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Discodermolide/Dictyostatin hybrids: synthesis and biological evaluation.
    Shin Y; Choy N; Turner TR; Balachandran R; Madiraju C; Day BW; Curran DP
    Org Lett; 2002 Dec; 4(25):4443-6. PubMed ID: 12465908
    [TBL] [Abstract][Full Text] [Related]  

  • 39. A strategy for exploiting the pseudosymmetry of the C1-C13 stretch of discodermolide.
    Parker KA; Katsoulis IA
    Org Lett; 2004 Apr; 6(9):1413-6. PubMed ID: 15101755
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Design, synthesis, and biological evaluation of potent discodermolide fluorescent and photoaffinity molecular probes.
    Smith AB; Rucker PV; Brouard I; Freeze BS; Xia S; Horwitz SB
    Org Lett; 2005 Nov; 7(23):5199-202. PubMed ID: 16268537
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 8.