BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

572 related articles for article (PubMed ID: 18339875)

  • 21. Migration of renal carcinoma cells is dependent on protein kinase Cdelta via beta1 integrin and focal adhesion kinase.
    Brenner W; Greber I; Gudejko-Thiel J; Beitz S; Schneider E; Walenta S; Peters K; Unger R; Thüroff JW
    Int J Oncol; 2008 May; 32(5):1125-31. PubMed ID: 18425341
    [TBL] [Abstract][Full Text] [Related]  

  • 22. TAE226, a dual inhibitor for FAK and IGF-IR, has inhibitory effects on mTOR signaling in esophageal cancer cells.
    Wang ZG; Fukazawa T; Nishikawa T; Watanabe N; Sakurama K; Motoki T; Takaoka M; Hatakeyama S; Omori O; Ohara T; Tanabe S; Fujiwara Y; Shirakawa Y; Yamatsuji T; Tanaka N; Naomoto Y
    Oncol Rep; 2008 Dec; 20(6):1473-7. PubMed ID: 19020730
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Tumor growth inhibition by synthetic and expressed siRNA targeting focal adhesion kinase.
    Tsutsumi K; Kasaoka T; Park HM; Nishiyama H; Nakajima M; Honda T
    Int J Oncol; 2008 Jul; 33(1):215-24. PubMed ID: 18575768
    [TBL] [Abstract][Full Text] [Related]  

  • 24. RNA interference-mediated silencing of focal adhesion kinase inhibits growth of human malignant glioma xenograft in nude mice.
    Wang GJ; Ma YP; Yang Y; Zhang N; Wang W; Liu SY; Chen LJ; Jiang Y; Zhao X; Wei YQ; Deng HX
    Cell Biol Int; 2011 Aug; 35(8):841-8. PubMed ID: 21247411
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Antitumor activity of a dual epidermal growth factor receptor and ErbB2 kinase inhibitor MP-412 (AV-412) in mouse xenograft models.
    Suzuki T; Fujii A; Ohya J; Nakamura H; Fujita F; Koike M; Fujita M
    Cancer Sci; 2009 Aug; 100(8):1526-31. PubMed ID: 19459856
    [TBL] [Abstract][Full Text] [Related]  

  • 26. CUDC-305, a novel synthetic HSP90 inhibitor with unique pharmacologic properties for cancer therapy.
    Bao R; Lai CJ; Qu H; Wang D; Yin L; Zifcak B; Atoyan R; Wang J; Samson M; Forrester J; DellaRocca S; Xu GX; Tao X; Zhai HX; Cai X; Qian C
    Clin Cancer Res; 2009 Jun; 15(12):4046-57. PubMed ID: 19509149
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Biological characterization of ARRY-142886 (AZD6244), a potent, highly selective mitogen-activated protein kinase kinase 1/2 inhibitor.
    Yeh TC; Marsh V; Bernat BA; Ballard J; Colwell H; Evans RJ; Parry J; Smith D; Brandhuber BJ; Gross S; Marlow A; Hurley B; Lyssikatos J; Lee PA; Winkler JD; Koch K; Wallace E
    Clin Cancer Res; 2007 Mar; 13(5):1576-83. PubMed ID: 17332304
    [TBL] [Abstract][Full Text] [Related]  

  • 28. A Cdc7 kinase inhibitor restricts initiation of DNA replication and has antitumor activity.
    Montagnoli A; Valsasina B; Croci V; Menichincheri M; Rainoldi S; Marchesi V; Tibolla M; Tenca P; Brotherton D; Albanese C; Patton V; Alzani R; Ciavolella A; Sola F; Molinari A; Volpi D; Avanzi N; Fiorentini F; Cattoni M; Healy S; Ballinari D; Pesenti E; Isacchi A; Moll J; Bensimon A; Vanotti E; Santocanale C
    Nat Chem Biol; 2008 Jun; 4(6):357-65. PubMed ID: 18469809
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Identification of methyl violet 2B as a novel blocker of focal adhesion kinase signaling pathway in cancer cells.
    Kim H; Kim ND; Lee J; Han G; Sim T
    Biochem Biophys Res Commun; 2013 Jul; 437(2):319-24. PubMed ID: 23817042
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Targeting Focal Adhesion Kinase and Resistance to mTOR Inhibition in Pancreatic Neuroendocrine Tumors.
    François RA; Maeng K; Nawab A; Kaye FJ; Hochwald SN; Zajac-Kaye M
    J Natl Cancer Inst; 2015 Aug; 107(8):. PubMed ID: 25971297
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Synthesis and evaluation of novel 7-azaindazolyl-indolyl-maleimide derivatives as antitumor agents and protein kinase C inhibitors.
    Ye Q; Cao J; Zhou X; Lv D; He Q; Yang B; Hu Y
    Bioorg Med Chem; 2009 Jul; 17(13):4763-72. PubMed ID: 19447039
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Doxycycline inhibits the adhesion and migration of melanoma cells by inhibiting the expression and phosphorylation of focal adhesion kinase (FAK).
    Sun T; Zhao N; Ni CS; Zhao XL; Zhang WZ; Su X; Zhang DF; Gu Q; Sun BC
    Cancer Lett; 2009 Nov; 285(2):141-50. PubMed ID: 19482420
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Signal transduction by focal adhesion kinase in cancer.
    Zhao J; Guan JL
    Cancer Metastasis Rev; 2009 Jun; 28(1-2):35-49. PubMed ID: 19169797
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Design, synthesis, and biological evaluation of pyrazolopyrimidine-sulfonamides as potent multiple-mitotic kinase (MMK) inhibitors (part I).
    Zhang L; Fan J; Chong JH; Cesena A; Tam BY; Gilson C; Boykin C; Wang D; Aivazian D; Marcotte D; Xiao G; Le Brazidec JY; Piao J; Lundgren K; Hong K; Vu K; Nguyen K; Gan LS; Silvian L; Ling L; Teng M; Reff M; Takeda N; Timple N; Wang Q; Morena R; Khan S; Zhao S; Li T; Lee WC; Taveras AG; Chao J
    Bioorg Med Chem Lett; 2011 Sep; 21(18):5633-7. PubMed ID: 21798738
    [TBL] [Abstract][Full Text] [Related]  

  • 35. The role of focal adhesion kinase catalytic activity on the proliferation and migration of squamous cell carcinoma cells.
    Serrels A; McLeod K; Canel M; Kinnaird A; Graham K; Frame MC; Brunton VG
    Int J Cancer; 2012 Jul; 131(2):287-97. PubMed ID: 21823119
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Fibronectin promotes invasiveness and focal adhesion kinase tyrosine phosphorylation of human colon cancer cell.
    Ding J; Li D; Wang X; Wang C; Wu T
    Hepatogastroenterology; 2008; 55(88):2072-6. PubMed ID: 19260479
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Inhibition of focal adhesion kinase suppresses the adverse phenotype of endocrine-resistant breast cancer cells and improves endocrine response in endocrine-sensitive cells.
    Hiscox S; Barnfather P; Hayes E; Bramble P; Christensen J; Nicholson RI; Barrett-Lee P
    Breast Cancer Res Treat; 2011 Feb; 125(3):659-69. PubMed ID: 20354780
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Pharmacologic blockade of FAK autophosphorylation decreases human glioblastoma tumor growth and synergizes with temozolomide.
    Golubovskaya VM; Huang G; Ho B; Yemma M; Morrison CD; Lee J; Eliceiri BP; Cance WG
    Mol Cancer Ther; 2013 Feb; 12(2):162-72. PubMed ID: 23243059
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Design, synthesis, and evaluation of novel imidazo[1,2-a][1,3,5]triazines and their derivatives as focal adhesion kinase inhibitors with antitumor activity.
    Dao P; Smith N; Tomkiewicz-Raulet C; Yen-Pon E; Camacho-Artacho M; Lietha D; Herbeuval JP; Coumoul X; Garbay C; Chen H
    J Med Chem; 2015 Jan; 58(1):237-51. PubMed ID: 25180654
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Optimization of 7-alkene-3-quinolinecarbonitriles as Src kinase inhibitors.
    Boschelli DH; Wang D; Wang Y; Wu B; Honores EE; Barrios Sosa AC; Chaudhary I; Golas J; Lucas J; Boschelli F
    Bioorg Med Chem Lett; 2010 May; 20(9):2924-7. PubMed ID: 20363128
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 29.