273 related articles for article (PubMed ID: 18343673)
1. Design, synthesis and pharmacological evaluation of hybrid molecules out of quinazolinimines and lipoic acid lead to highly potent and selective butyrylcholinesterase inhibitors with antioxidant properties.
Decker M; Kraus B; Heilmann J
Bioorg Med Chem; 2008 Apr; 16(8):4252-61. PubMed ID: 18343673
[TBL] [Abstract][Full Text] [Related]
2. Novel tricyclic quinazolinimines and related tetracyclic nitrogen bridgehead compounds as cholinesterase inhibitors with selectivity towards butyrylcholinesterase.
Decker M; Krauth F; Lehmann J
Bioorg Med Chem; 2006 Mar; 14(6):1966-77. PubMed ID: 16289855
[TBL] [Abstract][Full Text] [Related]
3. Rational approach to discover multipotent anti-Alzheimer drugs.
Rosini M; Andrisano V; Bartolini M; Bolognesi ML; Hrelia P; Minarini A; Tarozzi A; Melchiorre C
J Med Chem; 2005 Jan; 48(2):360-3. PubMed ID: 15658850
[TBL] [Abstract][Full Text] [Related]
4. Probing the mid-gorge of cholinesterases with spacer-modified bivalent quinazolinimines leads to highly potent and selective butyrylcholinesterase inhibitors.
Chen X; Tikhonova IG; Decker M
Bioorg Med Chem; 2011 Feb; 19(3):1222-35. PubMed ID: 21232964
[TBL] [Abstract][Full Text] [Related]
5. Design and synthesis of tacrine-ferulic acid hybrids as multi-potent anti-Alzheimer drug candidates.
Fang L; Kraus B; Lehmann J; Heilmann J; Zhang Y; Decker M
Bioorg Med Chem Lett; 2008 May; 18(9):2905-9. PubMed ID: 18406135
[TBL] [Abstract][Full Text] [Related]
6. Exploiting the lipoic acid structure in the search for novel multitarget ligands against Alzheimer's disease.
Rosini M; Simoni E; Bartolini M; Tarozzi A; Matera R; Milelli A; Hrelia P; Andrisano V; Bolognesi ML; Melchiorre C
Eur J Med Chem; 2011 Nov; 46(11):5435-42. PubMed ID: 21924801
[TBL] [Abstract][Full Text] [Related]
7. Homobivalent quinazolinimines as novel nanomolar inhibitors of cholinesterases with dirigible selectivity toward butyrylcholinesterase.
Decker M
J Med Chem; 2006 Sep; 49(18):5411-3. PubMed ID: 16942014
[TBL] [Abstract][Full Text] [Related]
8. Design and synthesis of antioxidant alpha-lipoic acid hybrids.
Koufaki M; Detsi A
Methods Mol Biol; 2010; 594():297-309. PubMed ID: 20072926
[TBL] [Abstract][Full Text] [Related]
9. Bis-(-)-nor-meptazinols as novel nanomolar cholinesterase inhibitors with high inhibitory potency on amyloid-beta aggregation.
Xie Q; Wang H; Xia Z; Lu M; Zhang W; Wang X; Fu W; Tang Y; Sheng W; Li W; Zhou W; Zhu X; Qiu Z; Chen H
J Med Chem; 2008 Apr; 51(7):2027-36. PubMed ID: 18333606
[TBL] [Abstract][Full Text] [Related]
10. Design, synthesis and evaluation of flavonoid derivatives as potent AChE inhibitors.
Sheng R; Lin X; Zhang J; Chol KS; Huang W; Yang B; He Q; Hu Y
Bioorg Med Chem; 2009 Sep; 17(18):6692-8. PubMed ID: 19692250
[TBL] [Abstract][Full Text] [Related]
11. Identification of a neuroprotective and selective butyrylcholinesterase inhibitor derived from the natural alkaloid evodiamine.
Huang G; Kling B; Darras FH; Heilmann J; Decker M
Eur J Med Chem; 2014 Jun; 81():15-21. PubMed ID: 24819955
[TBL] [Abstract][Full Text] [Related]
12. Synthesis, biological evaluation, and molecular modeling of berberine derivatives as potent acetylcholinesterase inhibitors.
Huang L; Shi A; He F; Li X
Bioorg Med Chem; 2010 Feb; 18(3):1244-51. PubMed ID: 20056426
[TBL] [Abstract][Full Text] [Related]
13. Design, synthesis and evaluation of isaindigotone derivatives as acetylcholinesterase and butyrylcholinesterase inhibitors.
Pan L; Tan JH; Hou JQ; Huang SL; Gu LQ; Huang ZS
Bioorg Med Chem Lett; 2008 Jul; 18(13):3790-3. PubMed ID: 18524585
[TBL] [Abstract][Full Text] [Related]
14. Chromone-lipoic acid conjugate: Neuroprotective agent having acceptable butyrylcholinesterase inhibition, antioxidant and copper-chelation activities.
Jalili-Baleh L; Nadri H; Forootanfar H; Küçükkılınç TT; Ayazgök B; Sharifzadeh M; Rahimifard M; Baeeri M; Abdollahi M; Foroumadi A; Khoobi M
Daru; 2021 Jun; 29(1):23-38. PubMed ID: 33420969
[TBL] [Abstract][Full Text] [Related]
15. Synthesis, biological evaluation of 9-N-substituted berberine derivatives as multi-functional agents of antioxidant, inhibitors of acetylcholinesterase, butyrylcholinesterase and amyloid-β aggregation.
Shan WJ; Huang L; Zhou Q; Meng FC; Li XS
Eur J Med Chem; 2011 Dec; 46(12):5885-93. PubMed ID: 22019228
[TBL] [Abstract][Full Text] [Related]
16. Cholinesterase inhibitors: SAR and enzyme inhibitory activity of 3-[omega-(benzylmethylamino)alkoxy]xanthen-9-ones.
Piazzi L; Belluti F; Bisi A; Gobbi S; Rizzo S; Bartolini M; Andrisano V; Recanatini M; Rampa A
Bioorg Med Chem; 2007 Jan; 15(1):575-85. PubMed ID: 17008100
[TBL] [Abstract][Full Text] [Related]
17. Synthesis of physostigmine analogues and evaluation of their anticholinesterase activities.
Zhan ZJ; Bian HL; Wang JW; Shan WG
Bioorg Med Chem Lett; 2010 Mar; 20(5):1532-4. PubMed ID: 20144867
[TBL] [Abstract][Full Text] [Related]
18. Synthesis, in vitro assay, and molecular modeling of new piperidine derivatives having dual inhibitory potency against acetylcholinesterase and Abeta1-42 aggregation for Alzheimer's disease therapeutics.
Kwon YE; Park JY; No KT; Shin JH; Lee SK; Eun JS; Yang JH; Shin TY; Kim DK; Chae BS; Leem JY; Kim KH
Bioorg Med Chem; 2007 Oct; 15(20):6596-607. PubMed ID: 17681794
[TBL] [Abstract][Full Text] [Related]
19. Synthesis of some new 3-coumaranone and coumarin derivatives as dual inhibitors of acetyl- and butyrylcholinesterase.
Alipour M; Khoobi M; Nadri H; Sakhteman A; Moradi A; Ghandi M; Foroumadi A; Shafiee A
Arch Pharm (Weinheim); 2013 Aug; 346(8):577-87. PubMed ID: 23852709
[TBL] [Abstract][Full Text] [Related]
20. Synthesis and biological evaluation of berberine-thiophenyl hybrids as multi-functional agents: Inhibition of acetylcholinesterase, butyrylcholinesterase, and Aβ aggregation and antioxidant activity.
Su T; Xie S; Wei H; Yan J; Huang L; Li X
Bioorg Med Chem; 2013 Sep; 21(18):5830-40. PubMed ID: 23932451
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]