BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

191 related articles for article (PubMed ID: 18343905)

  • 1. Structural insight into the inhibition of acetylcholinesterase by 2,3,4, 5-tetrahydro-1, 5-benzothiazepines.
    Nawaz SA; Umbreen S; Kahlid A; Ansari FL; Choudhary MI
    J Enzyme Inhib Med Chem; 2008 Apr; 23(2):206-12. PubMed ID: 18343905
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Withanolides, a new class of natural cholinesterase inhibitors with calcium antagonistic properties.
    Choudhary MI; Nawaz SA; ul-Haq Z; Lodhi MA; Ghayur MN; Jalil S; Riaz N; Yousuf S; Malik A; Gilani AH; ur-Rahman A
    Biochem Biophys Res Commun; 2005 Aug; 334(1):276-87. PubMed ID: 16108094
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Juliflorine: a potent natural peripheral anionic-site-binding inhibitor of acetylcholinesterase with calcium-channel blocking potential, a leading candidate for Alzheimer's disease therapy.
    Choudhary MI; Nawaz SA; Zaheer-ul-Haq ; Azim MK; Ghayur MN; Lodhi MA; Jalil S; Khalid A; Ahmed A; Rode BM; Atta-ur-Rahman ; Gilani AU; Ahmad VU
    Biochem Biophys Res Commun; 2005 Jul; 332(4):1171-7. PubMed ID: 16021692
    [TBL] [Abstract][Full Text] [Related]  

  • 4. In silico modeling of the specific inhibitory potential of thiophene-2,3-dihydro-1,5-benzothiazepine against BChE in the formation of beta-amyloid plaques associated with Alzheimer's disease.
    Ul-Haq Z; Khan W; Kalsoom S; Ansari FL
    Theor Biol Med Model; 2010 Jun; 7():22. PubMed ID: 20550720
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Kinetics and structure-activity relationship studies on pregnane-type steroidal alkaloids that inhibit cholinesterases.
    Khalid A; Zaheer-ul-Haq ; Anjum S; Khan MR; Atta-ur-Rahman ; Choudhary MI
    Bioorg Med Chem; 2004 May; 12(9):1995-2003. PubMed ID: 15080903
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Acetylcholinesterase complexed with bivalent ligands related to huperzine a: experimental evidence for species-dependent protein-ligand complementarity.
    Wong DM; Greenblatt HM; Dvir H; Carlier PR; Han YF; Pang YP; Silman I; Sussman JL
    J Am Chem Soc; 2003 Jan; 125(2):363-73. PubMed ID: 12517147
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis, biological activity, and docking studies of new acetylcholinesterase inhibitors of the bispyridinium type.
    Kapková P; Stiefl N; Sürig U; Engels B; Baumann K; Holzgrabe U
    Arch Pharm (Weinheim); 2003 Nov; 336(11):523-40. PubMed ID: 14639745
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Design, synthesis and biological evaluation of benzofuran appended benzothiazepine derivatives as inhibitors of butyrylcholinesterase and antimicrobial agents.
    Mostofi M; Mohammadi Ziarani G; Lashgari N
    Bioorg Med Chem; 2018 Jul; 26(12):3076-3095. PubMed ID: 29866481
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis, Biological Evaluation and Molecular Modelling of 2'-Hydroxychalcones as Acetylcholinesterase Inhibitors.
    Sukumaran SD; Chee CF; Viswanathan G; Buckle MJ; Othman R; Abd Rahman N; Chung LY
    Molecules; 2016 Jul; 21(7):. PubMed ID: 27455222
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Oxime-dipeptides as anticholinesterase, reactivator of phosphonylated-serine of AChE catalytic triad: probing the mechanistic insight by MM-GBSA, dynamics simulations and DFT analysis.
    Chadha N; Tiwari AK; Kumar V; Lal S; Milton MD; Mishra AK
    J Biomol Struct Dyn; 2015; 33(5):978-90. PubMed ID: 24805972
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Design, synthesis and evaluation of some N-methylenebenzenamine derivatives as selective acetylcholinesterase (AChE) inhibitor and antioxidant to enhance learning and memory.
    Shrivastava SK; Srivastava P; Upendra TVR; Tripathi PN; Sinha SK
    Bioorg Med Chem; 2017 Feb; 25(4):1471-1480. PubMed ID: 28126439
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Evaluation of the nature of camel retinal acetylcholinesterase: inhibition by hexamethonium.
    Alhomida AS; Kamal MA; al-Jafari AA
    J Enzyme Inhib; 1997 Dec; 12(4):303-11. PubMed ID: 9502051
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis, in vitro assay, and molecular modeling of new piperidine derivatives having dual inhibitory potency against acetylcholinesterase and Abeta1-42 aggregation for Alzheimer's disease therapeutics.
    Kwon YE; Park JY; No KT; Shin JH; Lee SK; Eun JS; Yang JH; Shin TY; Kim DK; Chae BS; Leem JY; Kim KH
    Bioorg Med Chem; 2007 Oct; 15(20):6596-607. PubMed ID: 17681794
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Syntheses and biological activities of chalcone and 1,5-benzothiazepine derivatives: promising new free-radical scavengers, and esterase, urease, and alpha-glucosidase inhibitors.
    Ansari FL; Umbreen S; Hussain L; Makhmoor T; Nawaz SA; Lodhi MA; Khan SN; Shaheen F; Choudhary MI;
    Chem Biodivers; 2005 Apr; 2(4):487-96. PubMed ID: 17191997
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The complex of a bivalent derivative of galanthamine with torpedo acetylcholinesterase displays drastic deformation of the active-site gorge: implications for structure-based drug design.
    Greenblatt HM; Guillou C; Guénard D; Argaman A; Botti S; Badet B; Thal C; Silman I; Sussman JL
    J Am Chem Soc; 2004 Dec; 126(47):15405-11. PubMed ID: 15563167
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The 'aromatic patch' of three proximal residues in the human acetylcholinesterase active centre allows for versatile interaction modes with inhibitors.
    Ariel N; Ordentlich A; Barak D; Bino T; Velan B; Shafferman A
    Biochem J; 1998 Oct; 335 ( Pt 1)(Pt 1):95-102. PubMed ID: 9742217
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Molecular docking and receptor-specific 3D-QSAR studies of acetylcholinesterase inhibitors.
    Deb PK; Sharma A; Piplani P; Akkinepally RR
    Mol Divers; 2012 Nov; 16(4):803-23. PubMed ID: 22996404
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Hopeahainol A binds reversibly at the acetylcholinesterase (AChE) peripheral site and inhibits enzyme activity with a novel higher order concentration dependence.
    Rosenberry TL; Martin PK; Nix AJ; Wildman SA; Cheung J; Snyder SA; Tan RX
    Chem Biol Interact; 2016 Nov; 259(Pt B):78-84. PubMed ID: 27297626
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Identification of Human Acetylcholinesterase Inhibitors from the Constituents of EGb761 by Modeling Docking and Molecular Dynamics Simulations.
    Zhang L; Li D; Cao F; Xiao W; Zhao L; Ding G; Wang ZZ
    Comb Chem High Throughput Screen; 2018; 21(1):41-49. PubMed ID: 29173156
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The nature of the inhibition of camel retina acetylcholinesterase (EC 3.1.1.7) activity by tetrahydroaminoacridine.
    al-Jafari AA
    J Ocul Pharmacol Ther; 1996; 12(4):503-14. PubMed ID: 8951687
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.