BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

193 related articles for article (PubMed ID: 18348982)

  • 1. Differential regulation of the IL-17 receptor by gammac cytokines: inhibitory signaling by the phosphatidylinositol 3-kinase pathway.
    Lindemann MJ; Hu Z; Benczik M; Liu KD; Gaffen SL
    J Biol Chem; 2008 May; 283(20):14100-8. PubMed ID: 18348982
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Late expression of granulysin by microbicidal CD4+ T cells requires PI3K- and STAT5-dependent expression of IL-2Rbeta that is defective in HIV-infected patients.
    Zheng CF; Jones GJ; Shi M; Wiseman JC; Marr KJ; Berenger BM; Huston SM; Gill MJ; Krensky AM; Kubes P; Mody CH
    J Immunol; 2008 Jun; 180(11):7221-9. PubMed ID: 18490721
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Anti-apoptotic signaling by the interleukin-2 receptor reveals a function for cytoplasmic tyrosine residues within the common gamma (gamma c) receptor subunit.
    Lindemann MJ; Benczik M; Gaffen SL
    J Biol Chem; 2003 Mar; 278(12):10239-49. PubMed ID: 12525482
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Interleukin-2 (IL-2)-mediated induction of the IL-2 receptor alpha chain gene. Critical role of two functionally redundant tyrosine residues in the IL-2 receptor beta chain cytoplasmic domain and suggestion that these residues mediate more than Stat5 activation.
    Ascherman DP; Migone TS; Friedmann MC; Leonard WJ
    J Biol Chem; 1997 Mar; 272(13):8704-9. PubMed ID: 9079703
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Functional cooperation of the interleukin-2 receptor beta chain and Jak1 in phosphatidylinositol 3-kinase recruitment and phosphorylation.
    Migone TS; Rodig S; Cacalano NA; Berg M; Schreiber RD; Leonard WJ
    Mol Cell Biol; 1998 Nov; 18(11):6416-22. PubMed ID: 9774657
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Isoproterenol-induced beta-2 adrenergic receptor activation negatively regulates interleukin-2 signaling.
    Ruiz-Medina BE; Cadena-Medina DA; Esparza E; Arrieta AJ; Kirken RA
    Biochem J; 2018 Sep; 475(18):2907-2923. PubMed ID: 30120106
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Novel regulation of CD80/CD86-induced phosphatidylinositol 3-kinase signaling by NOTCH1 protein in interleukin-6 and indoleamine 2,3-dioxygenase production by dendritic cells.
    Koorella C; Nair JR; Murray ME; Carlson LM; Watkins SK; Lee KP
    J Biol Chem; 2014 Mar; 289(11):7747-62. PubMed ID: 24415757
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Interleukin-2 Receptor β Thr-450 Phosphorylation Is a Positive Regulator for Receptor Complex Stability and Activation of Signaling Molecules.
    Ruiz-Medina BE; Ross JA; Kirken RA
    J Biol Chem; 2015 Aug; 290(34):20972-20983. PubMed ID: 26152718
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Delineation of the regions of interleukin-2 (IL-2) receptor beta chain important for association of Jak1 and Jak3. Jak1-independent functional recruitment of Jak3 to Il-2Rbeta.
    Zhu MH; Berry JA; Russell SM; Leonard WJ
    J Biol Chem; 1998 Apr; 273(17):10719-25. PubMed ID: 9553136
    [TBL] [Abstract][Full Text] [Related]  

  • 10. JAK-STAT and JAK-PI3K-mTORC1 pathways regulate telomerase transcriptionally and posttranslationally in ATL cells.
    Yamada O; Ozaki K; Akiyama M; Kawauchi K
    Mol Cancer Ther; 2012 May; 11(5):1112-21. PubMed ID: 22402124
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Upregulation of SLAMF3 on human T cells is induced by palmitic acid through the STAT5-PI3K/Akt pathway and features the chronic inflammatory profiles of type 2 diabetes.
    Zhou T; Wang G; Lyu Y; Wang L; Zuo S; Zou J; Sun L; Zhao W; Shu C; Yang YG; Hu Z
    Cell Death Dis; 2019 Jul; 10(8):559. PubMed ID: 31332162
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Enhanced interaction between SEC2 mutant and TCR Vβ induces MHC II-independent activation of T cells via PKCθ/NF-κB and IL-2R/STAT5 signaling pathways.
    Fu X; Xu M; Song Y; Li Y; Zhang H; Zhang J; Zhang C
    J Biol Chem; 2018 Dec; 293(51):19771-19784. PubMed ID: 30352872
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Acute lymphoblastic leukemia-associated JAK1 mutants activate the Janus kinase/STAT pathway via interleukin-9 receptor alpha homodimers.
    Hornakova T; Staerk J; Royer Y; Flex E; Tartaglia M; Constantinescu SN; Knoops L; Renauld JC
    J Biol Chem; 2009 Mar; 284(11):6773-81. PubMed ID: 19139102
    [TBL] [Abstract][Full Text] [Related]  

  • 14. IL-7: Comprehensive review.
    Winer H; Rodrigues GOL; Hixon JA; Aiello FB; Hsu TC; Wachter BT; Li W; Durum SK
    Cytokine; 2022 Dec; 160():156049. PubMed ID: 36201890
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Physician Education: The Erythropoietin Receptor and Signal Transduction.
    Yoshimura A; Arai K
    Oncologist; 1996; 1(5):337-339. PubMed ID: 10388012
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Interleukin-18 is a pro-hypertrophic cytokine that acts through a phosphatidylinositol 3-kinase-phosphoinositide-dependent kinase-1-Akt-GATA4 signaling pathway in cardiomyocytes.
    Chandrasekar B; Mummidi S; Claycomb WC; Mestril R; Nemer M
    J Biol Chem; 2005 Feb; 280(6):4553-67. PubMed ID: 15574430
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Deletion of the acidic-rich domain of the IL-2Rbeta chain increases receptor-associated PI3K activity.
    Ciprés A; Carrasco S; Mérida I
    FEBS Lett; 2001 Jun; 500(1-2):99-104. PubMed ID: 11434934
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Requirement for both JAK-mediated PI3K signaling and ACT1/TRAF6/TAK1-dependent NF-kappaB activation by IL-17A in enhancing cytokine expression in human airway epithelial cells.
    Huang F; Kao CY; Wachi S; Thai P; Ryu J; Wu R
    J Immunol; 2007 Nov; 179(10):6504-13. PubMed ID: 17982039
    [TBL] [Abstract][Full Text] [Related]  

  • 19. IL-2 activation of a PI3K-dependent STAT3 serine phosphorylation pathway in primary human T cells.
    Fung MM; Rohwer F; McGuire KL
    Cell Signal; 2003 Jun; 15(6):625-36. PubMed ID: 12681450
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Selective expansion of genetically modified T cells using an antibody/interleukin-2 receptor chimera.
    Sogo T; Kawahara M; Tsumoto K; Kumagai I; Ueda H; Nagamune T
    J Immunol Methods; 2008 Aug; 337(1):16-23. PubMed ID: 18589435
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.