BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

198 related articles for article (PubMed ID: 18366166)

  • 21. Synthesis of cryptophycin 52 using the sharpless asymmetric dihydroxylation: diol to epoxide transformation optimized for a base-sensitive substrate.
    Liang J; Moher ED; Moore RE; Hoard DW
    J Org Chem; 2000 May; 65(10):3143-7. PubMed ID: 10814209
    [TBL] [Abstract][Full Text] [Related]  

  • 22. A convergent synthesis of (+)-cryptophycin B, a potent antitumor macrolide from Nostoc sp. cyanobacteria.
    Ghosh AK; Bischoff A
    Org Lett; 2000 Jun; 2(11):1573-5. PubMed ID: 10841482
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Cryptophycin-induced hyperphosphorylation of Bcl-2, cell cycle arrest and growth inhibition in human H460 NSCLC cells.
    Lu K; Dempsey J; Schultz RM; Shih C; Teicher BA
    Cancer Chemother Pharmacol; 2001; 47(2):170-8. PubMed ID: 11269744
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Conformational changes in tubulin upon binding cryptophycin-52 reveal its mechanism of action.
    Eren E; Watts NR; Sackett DL; Wingfield PT
    J Biol Chem; 2021 Oct; 297(4):101138. PubMed ID: 34461087
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Preclinical anticancer activity of cryptophycin-8.
    Corbett TH; Valeriote FA; Demchik L; Polin L; Panchapor C; Pugh S; White K; Knight J; Jones J; Jones L; LoRusso P; Foster B; Wiegand RA; Lisow L; Golakoti T; Heltzel CE; Ogino J; Patterson GM; Moore RE
    J Exp Ther Oncol; 1996 Mar; 1(2):95-108. PubMed ID: 9414393
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Total synthesis of cryptophycin analogues via a scaffold approach.
    McCubbin JA; Maddess ML; Lautens M
    Org Lett; 2006 Jul; 8(14):2993-6. PubMed ID: 16805535
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Biological evaluation of cryptophycin 52 fragment A analogues: effect of the multidrug resistance ATP binding cassette transporters on antitumor activity.
    Al-Awar RS; Corbett TH; Ray JE; Polin L; Kennedy JH; Wagner MM; Williams DC
    Mol Cancer Ther; 2004 Sep; 3(9):1061-7. PubMed ID: 15367700
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Cryptophycin: a new antimicrotubule agent active against drug-resistant cells.
    Smith CD; Zhang X; Mooberry SL; Patterson GM; Moore RE
    Cancer Res; 1994 Jul; 54(14):3779-84. PubMed ID: 7913408
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Rapid entry into the cryptophycin core via an acyl-beta-lactam macrolactonization: total synthesis of cryptophycin-24.
    Eggen M; Nair SK; Georg GI
    Org Lett; 2001 Jun; 3(12):1813-5. PubMed ID: 11405718
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Complete Genome Sequence of the Cryptophycin-Producing Cyanobacterium
    Tippelt A; Busche T; Rückert C; Nett M
    Microbiol Resour Announc; 2020 Apr; 9(14):. PubMed ID: 32241855
    [No Abstract]   [Full Text] [Related]  

  • 31. Total synthesis and antitubulin activity of c10 analogues of cryptophycin-24.
    Buck SB; Huff JK; Himes RH; Georg GI
    J Med Chem; 2004 Jan; 47(3):696-702. PubMed ID: 14736249
    [TBL] [Abstract][Full Text] [Related]  

  • 32. The novel antimicrotubule agent cryptophycin 52 (LY355703) induces apoptosis via multiple pathways in human prostate cancer cells.
    Drew L; Fine RL; Do TN; Douglas GP; Petrylak DP
    Clin Cancer Res; 2002 Dec; 8(12):3922-32. PubMed ID: 12473608
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Mechanism of action cryptophycin. Interaction with the Vinca alkaloid domain of tubulin.
    Smith CD; Zhang X
    J Biol Chem; 1996 Mar; 271(11):6192-8. PubMed ID: 8626409
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Chemoenzymatic synthesis of cryptophycin anticancer agents by an ester bond-forming non-ribosomal peptide synthetase module.
    Ding Y; Rath CM; Bolduc KL; HÃ¥kansson K; Sherman DH
    J Am Chem Soc; 2011 Sep; 133(37):14492-5. PubMed ID: 21823639
    [TBL] [Abstract][Full Text] [Related]  

  • 35. In vitro effect of cryptophycin 52 on microtubule assembly and tubulin: molecular modeling of the mechanism of action of a new antimitotic drug.
    Barbier P; Gregoire C; Devred F; Sarrazin M; Peyrot V
    Biochemistry; 2001 Nov; 40(45):13510-9. PubMed ID: 11695898
    [TBL] [Abstract][Full Text] [Related]  

  • 36. EpoK, a cytochrome P450 involved in biosynthesis of the anticancer agents epothilones A and B. Substrate-mediated rescue of a P450 enzyme.
    Ogura H; Nishida CR; Hoch UR; Perera R; Dawson JH; Ortiz de Montellano PR
    Biochemistry; 2004 Nov; 43(46):14712-21. PubMed ID: 15544342
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Cryptophycin 1 binds to tubulin at a site distinct from the colchicine binding site and at a site that may overlap the vinca binding site.
    Mooberry SL; Taoka CR; Busquets L
    Cancer Lett; 1996 Oct; 107(1):53-7. PubMed ID: 8913266
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Total synthesis and anti-tubulin activity of epi-c3 analogues of cryptophycin-24.
    Buck SB; Huff JK; Himes RH; Georg GI
    J Med Chem; 2004 Jul; 47(14):3697-9. PubMed ID: 15214797
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Antiproliferative mechanism of action of cryptophycin-52: kinetic stabilization of microtubule dynamics by high-affinity binding to microtubule ends.
    Panda D; DeLuca K; Williams D; Jordan MA; Wilson L
    Proc Natl Acad Sci U S A; 1998 Aug; 95(16):9313-8. PubMed ID: 9689077
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Synthesis and cytotoxicity studies of new cryptophycin analogues.
    Liu WL; Zhang JC; Jiang FQ; Fu L
    Arch Pharm (Weinheim); 2009 Oct; 342(10):577-83. PubMed ID: 19714674
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 10.