BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

201 related articles for article (PubMed ID: 18367449)

  • 21. Silence superoxide dismutase 1 (SOD1): a promising therapeutic target for amyotrophic lateral sclerosis (ALS).
    Abati E; Bresolin N; Comi G; Corti S
    Expert Opin Ther Targets; 2020 Apr; 24(4):295-310. PubMed ID: 32125907
    [No Abstract]   [Full Text] [Related]  

  • 22. Lentiviral-mediated silencing of SOD1 through RNA interference retards disease onset and progression in a mouse model of ALS.
    Raoul C; Abbas-Terki T; Bensadoun JC; Guillot S; Haase G; Szulc J; Henderson CE; Aebischer P
    Nat Med; 2005 Apr; 11(4):423-8. PubMed ID: 15768028
    [TBL] [Abstract][Full Text] [Related]  

  • 23. RNAi therapy: dominant disease gene gets silenced.
    Xu Z; Xia XG
    Gene Ther; 2005 Aug; 12(15):1159-60. PubMed ID: 15858609
    [No Abstract]   [Full Text] [Related]  

  • 24. Human Cu/Zn superoxide dismutase (SOD1) overexpression in mice causes mitochondrial vacuolization, axonal degeneration, and premature motoneuron death and accelerates motoneuron disease in mice expressing a familial amyotrophic lateral sclerosis mutant SOD1.
    Jaarsma D; Haasdijk ED; Grashorn JA; Hawkins R; van Duijn W; Verspaget HW; London J; Holstege JC
    Neurobiol Dis; 2000 Dec; 7(6 Pt B):623-43. PubMed ID: 11114261
    [TBL] [Abstract][Full Text] [Related]  

  • 25. RNA interference protects against ALS in mouse model.
    Burton A
    Lancet Neurol; 2005 May; 4(5):274-5. PubMed ID: 15861555
    [No Abstract]   [Full Text] [Related]  

  • 26. Wild-type Cu/Zn superoxide dismutase (SOD1) does not facilitate, but impedes the formation of protein aggregates of amyotrophic lateral sclerosis causing mutant SOD1.
    Witan H; Gorlovoy P; Kaya AM; Koziollek-Drechsler I; Neumann H; Behl C; Clement AM
    Neurobiol Dis; 2009 Nov; 36(2):331-42. PubMed ID: 19660548
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Progressive impairment of CaV1.1 function in the skeletal muscle of mice expressing a mutant type 1 Cu/Zn superoxide dismutase (G93A) linked to amyotrophic lateral sclerosis.
    Beqollari D; Romberg CF; Dobrowolny G; Martini M; Voss AA; Musarò A; Bannister RA
    Skelet Muscle; 2016; 6():24. PubMed ID: 27340545
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Protein disulphide isomerase protects against protein aggregation and is S-nitrosylated in amyotrophic lateral sclerosis.
    Walker AK; Farg MA; Bye CR; McLean CA; Horne MK; Atkin JD
    Brain; 2010 Jan; 133(Pt 1):105-16. PubMed ID: 19903735
    [TBL] [Abstract][Full Text] [Related]  

  • 29. UCP2 overexpression worsens mitochondrial dysfunction and accelerates disease progression in a mouse model of amyotrophic lateral sclerosis.
    Peixoto PM; Kim HJ; Sider B; Starkov A; Horvath TL; Manfredi G
    Mol Cell Neurosci; 2013 Nov; 57():104-10. PubMed ID: 24141050
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Downregulation of Homer1b/c in SOD1 G93A Models of ALS: A Novel Mechanism of Neuroprotective Effect of Lithium and Valproic Acid.
    Jiang HZ; Wang SY; Yin X; Jiang HQ; Wang XD; Wang J; Wang TH; Qi Y; Yang YQ; Wang Y; Zhang CT; Feng HL
    Int J Mol Sci; 2016 Dec; 17(12):. PubMed ID: 27999308
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Different human copper-zinc superoxide dismutase mutants, SOD1G93A and SOD1H46R, exert distinct harmful effects on gross phenotype in mice.
    Pan L; Yoshii Y; Otomo A; Ogawa H; Iwasaki Y; Shang HF; Hadano S
    PLoS One; 2012; 7(3):e33409. PubMed ID: 22438926
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Widespread spinal cord transduction by intrathecal injection of rAAV delivers efficacious RNAi therapy for amyotrophic lateral sclerosis.
    Wang H; Yang B; Qiu L; Yang C; Kramer J; Su Q; Guo Y; Brown RH; Gao G; Xu Z
    Hum Mol Genet; 2014 Feb; 23(3):668-81. PubMed ID: 24108104
    [TBL] [Abstract][Full Text] [Related]  

  • 33. System xC- is a mediator of microglial function and its deletion slows symptoms in amyotrophic lateral sclerosis mice.
    Mesci P; Zaïdi S; Lobsiger CS; Millecamps S; Escartin C; Seilhean D; Sato H; Mallat M; Boillée S
    Brain; 2015 Jan; 138(Pt 1):53-68. PubMed ID: 25384799
    [TBL] [Abstract][Full Text] [Related]  

  • 34. RNA interference-mediated silencing of mutant superoxide dismutase rescues cyclosporin A-induced death in cultured neuroblastoma cells.
    Maxwell MM; Pasinelli P; Kazantsev AG; Brown RH
    Proc Natl Acad Sci U S A; 2004 Mar; 101(9):3178-83. PubMed ID: 14981234
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Coincident thresholds of mutant protein for paralytic disease and protein aggregation caused by restrictively expressed superoxide dismutase cDNA.
    Wang J; Xu G; Slunt HH; Gonzales V; Coonfield M; Fromholt D; Copeland NG; Jenkins NA; Borchelt DR
    Neurobiol Dis; 2005 Dec; 20(3):943-52. PubMed ID: 16046140
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Neuromuscular accumulation of mutant superoxide dismutase 1 aggregates in a transgenic mouse model of familial amyotrophic lateral sclerosis.
    Turner BJ; Lopes EC; Cheema SS
    Neurosci Lett; 2003 Oct; 350(2):132-6. PubMed ID: 12972170
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Adeno-associated virus-delivered artificial microRNA extends survival and delays paralysis in an amyotrophic lateral sclerosis mouse model.
    Stoica L; Todeasa SH; Cabrera GT; Salameh JS; ElMallah MK; Mueller C; Brown RH; Sena-Esteves M
    Ann Neurol; 2016 Apr; 79(4):687-700. PubMed ID: 26891182
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Impaired extracellular secretion of mutant superoxide dismutase 1 associates with neurotoxicity in familial amyotrophic lateral sclerosis.
    Turner BJ; Atkin JD; Farg MA; Zang DW; Rembach A; Lopes EC; Patch JD; Hill AF; Cheema SS
    J Neurosci; 2005 Jan; 25(1):108-17. PubMed ID: 15634772
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Phenotype of transgenic mice carrying a very low copy number of the mutant human G93A superoxide dismutase-1 gene associated with amyotrophic lateral sclerosis.
    Deitch JS; Alexander GM; Bensinger A; Yang S; Jiang JT; Heiman-Patterson TD
    PLoS One; 2014; 9(6):e99879. PubMed ID: 24945277
    [TBL] [Abstract][Full Text] [Related]  

  • 40. RNAi silencing in mouse models of neurodegenerative diseases.
    Farah MH
    Curr Drug Deliv; 2007 Apr; 4(2):161-7. PubMed ID: 17456035
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 11.