201 related articles for article (PubMed ID: 18367449)
21. Silence superoxide dismutase 1 (SOD1): a promising therapeutic target for amyotrophic lateral sclerosis (ALS).
Abati E; Bresolin N; Comi G; Corti S
Expert Opin Ther Targets; 2020 Apr; 24(4):295-310. PubMed ID: 32125907
[No Abstract] [Full Text] [Related]
22. Lentiviral-mediated silencing of SOD1 through RNA interference retards disease onset and progression in a mouse model of ALS.
Raoul C; Abbas-Terki T; Bensadoun JC; Guillot S; Haase G; Szulc J; Henderson CE; Aebischer P
Nat Med; 2005 Apr; 11(4):423-8. PubMed ID: 15768028
[TBL] [Abstract][Full Text] [Related]
23. RNAi therapy: dominant disease gene gets silenced.
Xu Z; Xia XG
Gene Ther; 2005 Aug; 12(15):1159-60. PubMed ID: 15858609
[No Abstract] [Full Text] [Related]
24. Human Cu/Zn superoxide dismutase (SOD1) overexpression in mice causes mitochondrial vacuolization, axonal degeneration, and premature motoneuron death and accelerates motoneuron disease in mice expressing a familial amyotrophic lateral sclerosis mutant SOD1.
Jaarsma D; Haasdijk ED; Grashorn JA; Hawkins R; van Duijn W; Verspaget HW; London J; Holstege JC
Neurobiol Dis; 2000 Dec; 7(6 Pt B):623-43. PubMed ID: 11114261
[TBL] [Abstract][Full Text] [Related]
25. RNA interference protects against ALS in mouse model.
Burton A
Lancet Neurol; 2005 May; 4(5):274-5. PubMed ID: 15861555
[No Abstract] [Full Text] [Related]
26. Wild-type Cu/Zn superoxide dismutase (SOD1) does not facilitate, but impedes the formation of protein aggregates of amyotrophic lateral sclerosis causing mutant SOD1.
Witan H; Gorlovoy P; Kaya AM; Koziollek-Drechsler I; Neumann H; Behl C; Clement AM
Neurobiol Dis; 2009 Nov; 36(2):331-42. PubMed ID: 19660548
[TBL] [Abstract][Full Text] [Related]
27. Progressive impairment of CaV1.1 function in the skeletal muscle of mice expressing a mutant type 1 Cu/Zn superoxide dismutase (G93A) linked to amyotrophic lateral sclerosis.
Beqollari D; Romberg CF; Dobrowolny G; Martini M; Voss AA; Musarò A; Bannister RA
Skelet Muscle; 2016; 6():24. PubMed ID: 27340545
[TBL] [Abstract][Full Text] [Related]
28. Protein disulphide isomerase protects against protein aggregation and is S-nitrosylated in amyotrophic lateral sclerosis.
Walker AK; Farg MA; Bye CR; McLean CA; Horne MK; Atkin JD
Brain; 2010 Jan; 133(Pt 1):105-16. PubMed ID: 19903735
[TBL] [Abstract][Full Text] [Related]
29. UCP2 overexpression worsens mitochondrial dysfunction and accelerates disease progression in a mouse model of amyotrophic lateral sclerosis.
Peixoto PM; Kim HJ; Sider B; Starkov A; Horvath TL; Manfredi G
Mol Cell Neurosci; 2013 Nov; 57():104-10. PubMed ID: 24141050
[TBL] [Abstract][Full Text] [Related]
30. Downregulation of Homer1b/c in SOD1 G93A Models of ALS: A Novel Mechanism of Neuroprotective Effect of Lithium and Valproic Acid.
Jiang HZ; Wang SY; Yin X; Jiang HQ; Wang XD; Wang J; Wang TH; Qi Y; Yang YQ; Wang Y; Zhang CT; Feng HL
Int J Mol Sci; 2016 Dec; 17(12):. PubMed ID: 27999308
[TBL] [Abstract][Full Text] [Related]
31. Different human copper-zinc superoxide dismutase mutants, SOD1G93A and SOD1H46R, exert distinct harmful effects on gross phenotype in mice.
Pan L; Yoshii Y; Otomo A; Ogawa H; Iwasaki Y; Shang HF; Hadano S
PLoS One; 2012; 7(3):e33409. PubMed ID: 22438926
[TBL] [Abstract][Full Text] [Related]
32. Widespread spinal cord transduction by intrathecal injection of rAAV delivers efficacious RNAi therapy for amyotrophic lateral sclerosis.
Wang H; Yang B; Qiu L; Yang C; Kramer J; Su Q; Guo Y; Brown RH; Gao G; Xu Z
Hum Mol Genet; 2014 Feb; 23(3):668-81. PubMed ID: 24108104
[TBL] [Abstract][Full Text] [Related]
33. System xC- is a mediator of microglial function and its deletion slows symptoms in amyotrophic lateral sclerosis mice.
Mesci P; Zaïdi S; Lobsiger CS; Millecamps S; Escartin C; Seilhean D; Sato H; Mallat M; Boillée S
Brain; 2015 Jan; 138(Pt 1):53-68. PubMed ID: 25384799
[TBL] [Abstract][Full Text] [Related]
34. RNA interference-mediated silencing of mutant superoxide dismutase rescues cyclosporin A-induced death in cultured neuroblastoma cells.
Maxwell MM; Pasinelli P; Kazantsev AG; Brown RH
Proc Natl Acad Sci U S A; 2004 Mar; 101(9):3178-83. PubMed ID: 14981234
[TBL] [Abstract][Full Text] [Related]
35. Coincident thresholds of mutant protein for paralytic disease and protein aggregation caused by restrictively expressed superoxide dismutase cDNA.
Wang J; Xu G; Slunt HH; Gonzales V; Coonfield M; Fromholt D; Copeland NG; Jenkins NA; Borchelt DR
Neurobiol Dis; 2005 Dec; 20(3):943-52. PubMed ID: 16046140
[TBL] [Abstract][Full Text] [Related]
36. Neuromuscular accumulation of mutant superoxide dismutase 1 aggregates in a transgenic mouse model of familial amyotrophic lateral sclerosis.
Turner BJ; Lopes EC; Cheema SS
Neurosci Lett; 2003 Oct; 350(2):132-6. PubMed ID: 12972170
[TBL] [Abstract][Full Text] [Related]
37. Adeno-associated virus-delivered artificial microRNA extends survival and delays paralysis in an amyotrophic lateral sclerosis mouse model.
Stoica L; Todeasa SH; Cabrera GT; Salameh JS; ElMallah MK; Mueller C; Brown RH; Sena-Esteves M
Ann Neurol; 2016 Apr; 79(4):687-700. PubMed ID: 26891182
[TBL] [Abstract][Full Text] [Related]
38. Impaired extracellular secretion of mutant superoxide dismutase 1 associates with neurotoxicity in familial amyotrophic lateral sclerosis.
Turner BJ; Atkin JD; Farg MA; Zang DW; Rembach A; Lopes EC; Patch JD; Hill AF; Cheema SS
J Neurosci; 2005 Jan; 25(1):108-17. PubMed ID: 15634772
[TBL] [Abstract][Full Text] [Related]
39. Phenotype of transgenic mice carrying a very low copy number of the mutant human G93A superoxide dismutase-1 gene associated with amyotrophic lateral sclerosis.
Deitch JS; Alexander GM; Bensinger A; Yang S; Jiang JT; Heiman-Patterson TD
PLoS One; 2014; 9(6):e99879. PubMed ID: 24945277
[TBL] [Abstract][Full Text] [Related]
40. RNAi silencing in mouse models of neurodegenerative diseases.
Farah MH
Curr Drug Deliv; 2007 Apr; 4(2):161-7. PubMed ID: 17456035
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]