BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

406 related articles for article (PubMed ID: 18367457)

  • 1. Antiarrhythmic properties of a rapid delayed-rectifier current activator in rabbit models of acquired long QT syndrome.
    Diness TG; Yeh YH; Qi XY; Chartier D; Tsuji Y; Hansen RS; Olesen SP; Grunnet M; Nattel S
    Cardiovasc Res; 2008 Jul; 79(1):61-9. PubMed ID: 18367457
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Calcium antagonist property of CPU228, a dofetilide derivative, contributes to its low incidence of torsades de pointes in rabbits.
    Huang ZJ; Dai DZ; Li N; Na T; Ji M; Dai Y
    Clin Exp Pharmacol Physiol; 2007 Apr; 34(4):310-7. PubMed ID: 17324143
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Beat-by-beat QT interval variability, but not QT prolongation per se, predicts drug-induced torsades de pointes in the anaesthetised methoxamine-sensitized rabbit.
    Jacobson I; Carlsson L; Duker G
    J Pharmacol Toxicol Methods; 2011; 63(1):40-6. PubMed ID: 20451633
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A new biomarker--index of cardiac electrophysiological balance (iCEB)--plays an important role in drug-induced cardiac arrhythmias: beyond QT-prolongation and Torsades de Pointes (TdPs).
    Lu HR; Yan GX; Gallacher DJ
    J Pharmacol Toxicol Methods; 2013; 68(2):250-259. PubMed ID: 23337247
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Potassium channel subunit remodeling in rabbits exposed to long-term bradycardia or tachycardia: discrete arrhythmogenic consequences related to differential delayed-rectifier changes.
    Tsuji Y; Zicha S; Qi XY; Kodama I; Nattel S
    Circulation; 2006 Jan; 113(3):345-55. PubMed ID: 16432066
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Combined pharmacological block of I(Kr) and I(Ks) increases short-term QT interval variability and provokes torsades de pointes.
    Lengyel C; Varró A; Tábori K; Papp JG; Baczkó I
    Br J Pharmacol; 2007 Aug; 151(7):941-51. PubMed ID: 17533421
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Late na(+) current inhibition by ranolazine reduces torsades de pointes in the chronic atrioventricular block dog model.
    Antoons G; Oros A; Beekman JD; Engelen MA; Houtman MJ; Belardinelli L; Stengl M; Vos MA
    J Am Coll Cardiol; 2010 Feb; 55(8):801-9. PubMed ID: 20170820
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Assessment of the ion channel-blocking profile of the novel combined ion channel blocker AZD1305 and its proarrhythmic potential versus dofetilide in the methoxamine-sensitized rabbit in vivo.
    Carlsson L; Andersson B; Linhardt G; Löfberg L
    J Cardiovasc Pharmacol; 2009 Jul; 54(1):82-9. PubMed ID: 19528812
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Comparison of the IKr blockers moxifloxacin, dofetilide and E-4031 in five screening models of pro-arrhythmia reveals lack of specificity of isolated cardiomyocytes.
    Nalos L; Varkevisser R; Jonsson MK; Houtman MJ; Beekman JD; van der Nagel R; Thomsen MB; Duker G; Sartipy P; de Boer TP; Peschar M; Rook MB; van Veen TA; van der Heyden MA; Vos MA
    Br J Pharmacol; 2012 Jan; 165(2):467-78. PubMed ID: 21718297
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Comparative pharmacology of guinea pig cardiac myocyte and cloned hERG (I(Kr)) channel.
    Davie C; Pierre-Valentin J; Pollard C; Standen N; Mitcheson J; Alexander P; Thong B
    J Cardiovasc Electrophysiol; 2004 Nov; 15(11):1302-9. PubMed ID: 15574182
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The electromechanical window is no better than QT prolongation to assess risk of Torsade de Pointes in the complete atrioventricular block model in dogs.
    Stams TR; Bourgonje VJ; Beekman HD; Schoenmakers M; van der Nagel R; Oosterhoff P; van Opstal JM; Vos MA
    Br J Pharmacol; 2014 Feb; 171(3):714-22. PubMed ID: 24490860
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Nonselective I(Kr)-blockers do not induce torsades de pointes in the anesthetized rabbit during alpha1-adrenoceptor stimulation.
    Lu HR; Remeysen P; De Clerck F
    J Cardiovasc Pharmacol; 2000 Dec; 36(6):728-36. PubMed ID: 11117372
    [TBL] [Abstract][Full Text] [Related]  

  • 13. AV-block and conduction slowing prevail over TdP arrhythmias in the methoxamine-sensitized pro-arrhythmic rabbit model.
    Varkevisser R; Vos MA; Beekman JD; Tieland RG; Van Der Heyden MA
    J Cardiovasc Electrophysiol; 2015 Jan; 26(1):82-9. PubMed ID: 25154623
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Ionic mechanisms of acquired QT prolongation and torsades de pointes in rabbits with chronic complete atrioventricular block.
    Tsuji Y; Opthof T; Yasui K; Inden Y; Takemura H; Niwa N; Lu Z; Lee JK; Honjo H; Kamiya K; Kodama I
    Circulation; 2002 Oct; 106(15):2012-8. PubMed ID: 12370228
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Assessment of the proarrhythmic potential of the novel antiarrhythmic agent AZD7009 and dofetilide in experimental models of torsades de pointes.
    Wu Y; Carlsson L; Liu T; Kowey PR; Yan GX
    J Cardiovasc Electrophysiol; 2005 Aug; 16(8):898-904. PubMed ID: 16101634
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synergistic Effect of Dofetilide and Mexiletine on Prevention of Atrial Fibrillation.
    Liu G; Xue X; Gao C; Huang J; Qi D; Zhang Y; Dong JZ; Ma CS; Yan GX
    J Am Heart Assoc; 2017 May; 6(5):. PubMed ID: 28522677
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Dofetilide-induced long QT and torsades de pointes.
    Aktas MK; Shah AH; Akiyama T
    Ann Noninvasive Electrocardiol; 2007 Jul; 12(3):197-202. PubMed ID: 17617063
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Cellular and ionic mechanism for drug-induced long QT syndrome and effectiveness of verapamil.
    Aiba T; Shimizu W; Inagaki M; Noda T; Miyoshi S; Ding WG; Zankov DP; Toyoda F; Matsuura H; Horie M; Sunagawa K
    J Am Coll Cardiol; 2005 Jan; 45(2):300-7. PubMed ID: 15653031
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Female gender does not influence the magnitude of ibutilide-induced repolarization delay and incidence of torsades de pointes in an in vivo rabbit model of the acquired long QT syndrome.
    Johansson M; Carlsson L
    J Cardiovasc Pharmacol Ther; 2001 Jul; 6(3):247-54. PubMed ID: 11584331
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Ventricular remodelling is a prerequisite for the induction of dofetilide-induced torsade de pointes arrhythmias in the anaesthetized, complete atrio-ventricular-block dog.
    Dunnink A; van Opstal JM; Oosterhoff P; Winckels SK; Beekman JD; van der Nagel R; Cora Verduyn S; Vos MA
    Europace; 2012 Mar; 14(3):431-6. PubMed ID: 21946817
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 21.