BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

285 related articles for article (PubMed ID: 18372000)

  • 1. Inhibition of aryl hydrocarbon receptor transactivation and DNA adduct formation by CYP1 isoform-selective metabolic deactivation of benzo[a]pyrene.
    Endo K; Uno S; Seki T; Ariga T; Kusumi Y; Mitsumata M; Yamada S; Makishima M
    Toxicol Appl Pharmacol; 2008 Jul; 230(2):135-43. PubMed ID: 18372000
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Benzo[g,h,i]perylene synergistically transactivates benzo[a]pyrene-induced CYP1A1 gene expression by aryl hydrocarbon receptor pathway.
    Cherng SH; Lin P; Yang JL; Hsu SL; Lee H
    Toxicol Appl Pharmacol; 2001 Jan; 170(1):63-8. PubMed ID: 11141357
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Polycyclic aromatic hydrocarbon-inducible DNA adducts: evidence by 32P-postlabeling and use of knockout mice for Ah receptor-independent mechanisms of metabolic activation in vivo.
    Kondraganti SR; Fernandez-Salguero P; Gonzalez FJ; Ramos KS; Jiang W; Moorthy B
    Int J Cancer; 2003 Jan; 103(1):5-11. PubMed ID: 12455047
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Resveratrol, a natural aryl hydrocarbon receptor antagonist, protects lung from DNA damage and apoptosis caused by benzo[a]pyrene.
    Revel A; Raanani H; Younglai E; Xu J; Rogers I; Han R; Savouret JF; Casper RF
    J Appl Toxicol; 2003; 23(4):255-61. PubMed ID: 12884409
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Benzo[a]pyrene-induced toxicity: paradoxical protection in Cyp1a1(-/-) knockout mice having increased hepatic BaP-DNA adduct levels.
    Uno S; Dalton TP; Shertzer HG; Genter MB; Warshawsky D; Talaska G; Nebert DW
    Biochem Biophys Res Commun; 2001 Dec; 289(5):1049-56. PubMed ID: 11741297
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Induction of CYP1A1 and CYP1B1 and formation of carcinogen-DNA adducts in normal human mammary epithelial cells treated with benzo[a]pyrene.
    Keshava C; Divi RL; Whipkey DL; Frye BL; McCanlies E; Kuo M; Poirier MC; Weston A
    Cancer Lett; 2005 Apr; 221(2):213-24. PubMed ID: 15808407
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Induction of CYP1A1, CYP1A2, and CYP1B1 mRNAs by nitropolycyclic aromatic hydrocarbons in various human tissue-derived cells: chemical-, cytochrome P450 isoform-, and cell-specific differences.
    Iwanari M; Nakajima M; Kizu R; Hayakawa K; Yokoi T
    Arch Toxicol; 2002 Jun; 76(5-6):287-98. PubMed ID: 12107646
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Preferential induction of CYP1B1 by benzo[a]pyrene in human oral epithelial cells: impact on DNA adduct formation and prevention by polyphenols.
    Wen X; Walle T
    Carcinogenesis; 2005 Oct; 26(10):1774-81. PubMed ID: 15905203
    [TBL] [Abstract][Full Text] [Related]  

  • 9. DNA adduct formation in precision-cut rat liver and lung slices exposed to benzo[a]pyrene.
    Harrigan JA; Vezina CM; McGarrigle BP; Ersing N; Box HC; Maccubbin AE; Olson JR
    Toxicol Sci; 2004 Feb; 77(2):307-14. PubMed ID: 14691214
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Induction of CYP1A1 and CYP1B1 in liver and lung by benzo(a)pyrene and 7,12-d imethylbenz(a)anthracene do not affect distribution of polycyclic hydrocarbons to target tissue: role of AhR and CYP1B1 in bone marrow cytotoxicity.
    Galván N; Teske DE; Zhou G; Moorthy B; MacWilliams PS; Czuprynski CJ; Jefcoate CR
    Toxicol Appl Pharmacol; 2005 Feb; 202(3):244-57. PubMed ID: 15667830
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Glycine N-methyltransferase tumor susceptibility gene in the benzo(a)pyrene-detoxification pathway.
    Chen SY; Lin JR; Darbha R; Lin P; Liu TY; Chen YM
    Cancer Res; 2004 May; 64(10):3617-23. PubMed ID: 15150120
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Inhibition of aryl hydrocarbon-induced cytochrome P-450 1A1 enzyme activity and CYP1A1 expression by resveratrol.
    Ciolino HP; Yeh GC
    Mol Pharmacol; 1999 Oct; 56(4):760-7. PubMed ID: 10496959
    [TBL] [Abstract][Full Text] [Related]  

  • 13. 5,7-Dimethoxyflavone downregulates CYP1A1 expression and benzo[a]pyrene-induced DNA binding in Hep G2 cells.
    Wen X; Walle UK; Walle T
    Carcinogenesis; 2005 Apr; 26(4):803-9. PubMed ID: 15661813
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Differential inhibition and inactivation of human CYP1 enzymes by trans-resveratrol: evidence for mechanism-based inactivation of CYP1A2.
    Chang TK; Chen J; Lee WB
    J Pharmacol Exp Ther; 2001 Dec; 299(3):874-82. PubMed ID: 11714871
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Resveratrol, a natural aryl hydrocarbon receptor antagonist, protects sperm from DNA damage and apoptosis caused by benzo(a)pyrene.
    Revel A; Raanani H; Younglai E; Xu J; Han R; Savouret JF; Casper RF
    Reprod Toxicol; 2001; 15(5):479-86. PubMed ID: 11780955
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Induction of CYP1A1 and CYP1B1 in T-47D human breast cancer cells by benzo[a]pyrene is diminished by arsenite.
    Spink DC; Katz BH; Hussain MM; Spink BC; Wu SJ; Liu N; Pause R; Kaminsky LS
    Drug Metab Dispos; 2002 Mar; 30(3):262-9. PubMed ID: 11854143
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Curcumin activates the aryl hydrocarbon receptor yet significantly inhibits (-)-benzo(a)pyrene-7R-trans-7,8-dihydrodiol bioactivation in oral squamous cell carcinoma cells and oral mucosa.
    Rinaldi AL; Morse MA; Fields HW; Rothas DA; Pei P; Rodrigo KA; Renner RJ; Mallery SR
    Cancer Res; 2002 Oct; 62(19):5451-6. PubMed ID: 12359752
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Benzo(a)pyrene diolepoxide (BPDE)-DNA adduct levels in leukocytes of smokers in relation to polymorphism of CYP1A1, GSTM1, GSTP1, GSTT1, and mEH.
    Lodovici M; Luceri C; Guglielmi F; Bacci C; Akpan V; Fonnesu ML; Boddi V; Dolara P
    Cancer Epidemiol Biomarkers Prev; 2004 Aug; 13(8):1342-8. PubMed ID: 15298956
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Inhibition of carcinogen-bioactivating cytochrome P450 1 isoforms by amiloride derivatives.
    Sparfel L; Huc L; Le Vee M; Desille M; Lagadic-Gossmann D; Fardel O
    Biochem Pharmacol; 2004 May; 67(9):1711-9. PubMed ID: 15081870
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Role of cytochrome p4501 family members in the metabolic activation of polycyclic aromatic hydrocarbons in mouse epidermis.
    Kleiner HE; Vulimiri SV; Hatten WB; Reed MJ; Nebert DW; Jefcoate CR; DiGiovanni J
    Chem Res Toxicol; 2004 Dec; 17(12):1667-74. PubMed ID: 15606143
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.