BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

243 related articles for article (PubMed ID: 18372400)

  • 1. Disposition of lasofoxifene, a next-generation selective estrogen receptor modulator, in healthy male subjects.
    Prakash C; Johnson KA; Gardner MJ
    Drug Metab Dispos; 2008 Jul; 36(7):1218-26. PubMed ID: 18372400
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Metabolism, distribution, and excretion of a next generation selective estrogen receptor modulator, lasofoxifene, in rats and monkeys.
    Prakash C; Johnson KA; Schroeder CM; Potchoiba MJ
    Drug Metab Dispos; 2008 Sep; 36(9):1753-69. PubMed ID: 18515329
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A single-dose pharmacokinetic study of lasofoxifene in healthy volunteers and subjects with mild and moderate hepatic impairment.
    Bramson C; Ouellet D; Roman D; Randinitis E; Gardner MJ
    J Clin Pharmacol; 2006 Jan; 46(1):29-36. PubMed ID: 16397281
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Clinical pharmacology of multiple doses of lasofoxifene in postmenopausal women.
    Gardner M; Taylor A; Wei G; Calcagni A; Duncan B; Milton A
    J Clin Pharmacol; 2006 Jan; 46(1):52-8. PubMed ID: 16397284
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Metabolism, disposition, excretion, and pharmacokinetics of levormeloxifene, a selective estrogen receptor modulator, in the rat.
    Mountfield RJ; Kiehr B; John BA
    Drug Metab Dispos; 2000 May; 28(5):503-13. PubMed ID: 10772628
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Pimecrolimus: absorption, distribution, metabolism, and excretion in healthy volunteers after a single oral dose and supplementary investigations in vitro.
    Zollinger M; Waldmeier F; Hartmann S; Zenke G; Zimmerlin AG; Glaenzel U; Baldeck JP; Schweitzer A; Berthier S; Moenius T; Grassberger MA
    Drug Metab Dispos; 2006 May; 34(5):765-74. PubMed ID: 16467136
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Metabolism, pharmacokinetics, and excretion of the substance P receptor antagonist CP-122,721 in humans: structural characterization of the novel major circulating metabolite 5-trifluoromethoxy salicylic acid by high-performance liquid chromatography-tandem mass spectrometry and NMR spectroscopy.
    Colizza K; Awad M; Kamel A
    Drug Metab Dispos; 2007 Jun; 35(6):884-97. PubMed ID: 17360832
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Absorption, metabolism, and excretion of [14C]imidafenacin, a new compound for treatment of overactive bladder, after oral administration to healthy male subjects.
    Ohmori S; Miura M; Toriumi C; Satoh Y; Ooie T
    Drug Metab Dispos; 2007 Sep; 35(9):1624-33. PubMed ID: 17567733
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Effects of steady-state lasofoxifene on CYP2D6- and CYP2E1-mediated metabolism.
    Moller RA; Fisher JM; Taylor AE; Kolluri S; Gardner MJ; Obach RS; Walsky RL
    Ann Pharmacother; 2006 Jan; 40(1):32-7. PubMed ID: 16368922
    [TBL] [Abstract][Full Text] [Related]  

  • 10. CYP2C8- and CYP3A-mediated C-demethylation of (3-{[(4-tert-butylbenzyl)-(pyridine-3-sulfonyl)-amino]-methyl}-phenoxy)-acetic acid (CP-533,536), an EP2 receptor-selective prostaglandin E2 agonist: characterization of metabolites by high-resolution liquid chromatography-tandem mass spectrometry and liquid chromatography/mass spectrometry-nuclear magnetic resonance.
    Prakash C; Wang W; O'Connell T; Johnson KA
    Drug Metab Dispos; 2008 Oct; 36(10):2093-103. PubMed ID: 18653741
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Effect of lasofoxifene on the pharmacokinetics of digoxin in healthy postmenopausal women.
    Roman D; Bramson C; Ouellet D; Randinitis E; Gardner M
    J Clin Pharmacol; 2005 Dec; 45(12):1407-12. PubMed ID: 16291716
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Metabolism and excretion of a new antianxiety drug candidate, CP-93,393, in cynomolgus monkeys: identification of the novel pyrimidine ring cleaved metabolites.
    Prakash C; Cui D
    Drug Metab Dispos; 1997 Dec; 25(12):1395-406. PubMed ID: 9394030
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Pharmacokinetic parameters of tibolone and metabolites in plasma, urine, feces, and bile from ovariectomized cynomolgus monkeys after a single dose or multiple doses of tibolone.
    Verheul HA; Timmer CJ; van Iersel ML; Delbressine LP; Kloosterboer HJ
    Drug Metab Dispos; 2007 Jul; 35(7):1112-8. PubMed ID: 17420282
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Embryo/fetal toxicity assessment of lasofoxifene, a selective estrogen receptor modulator (SERM), in rats and rabbits.
    Ozolins TR; Gupta U
    Birth Defects Res B Dev Reprod Toxicol; 2004 Jun; 71(3):161-70. PubMed ID: 15282737
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Human metabolism of nebicapone (BIA 3-202), a novel catechol-o-methyltransferase inhibitor: characterization of in vitro glucuronidation.
    Loureiro AI; Bonifácio MJ; Fernandes-Lopes C; Almeida L; Wright LC; Soares-Da-Silva P
    Drug Metab Dispos; 2006 Nov; 34(11):1856-62. PubMed ID: 16790555
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Metabolism and disposition in humans of raltegravir (MK-0518), an anti-AIDS drug targeting the human immunodeficiency virus 1 integrase enzyme.
    Kassahun K; McIntosh I; Cui D; Hreniuk D; Merschman S; Lasseter K; Azrolan N; Iwamoto M; Wagner JA; Wenning LA
    Drug Metab Dispos; 2007 Sep; 35(9):1657-63. PubMed ID: 17591678
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Selective estrogen receptor modulator (SERM) lasofoxifene forms reactive quinones similar to estradiol.
    Michalsen BT; Gherezghiher TB; Choi J; Chandrasena RE; Qin Z; Thatcher GR; Bolton JL
    Chem Res Toxicol; 2012 Jul; 25(7):1472-83. PubMed ID: 22642258
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Metabolism, distribution and excretion of a selective N-methyl-D-aspartate receptor antagonist, traxoprodil, in rats and dogs.
    Prakash C; Cui D; Potchoiba MJ; Butler T
    Drug Metab Dispos; 2007 Aug; 35(8):1350-64. PubMed ID: 17496205
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Reproductive toxicity assessment of lasofoxifene, a selective estrogen receptor modulator (SERM), in female rats.
    Terry KK; Cappon GD; Hurtt ME; Tassinari MS; Gupta U
    Birth Defects Res B Dev Reprod Toxicol; 2004 Jun; 71(3):150-60. PubMed ID: 15282736
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Studies on the metabolism of the novel, selective cyclooxygenase-2 inhibitor indomethacin phenethylamide in rat, mouse, and human liver microsomes: identification of active metabolites.
    Remmel RP; Crews BC; Kozak KR; Kalgutkar AS; Marnett LJ
    Drug Metab Dispos; 2004 Jan; 32(1):113-22. PubMed ID: 14709628
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.