BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

366 related articles for article (PubMed ID: 18373353)

  • 1. Thermodynamic characterization of allosteric glycogen phosphorylase inhibitors.
    Anderka O; Loenze P; Klabunde T; Dreyer MK; Defossa E; Wendt KU; Schmoll D
    Biochemistry; 2008 Apr; 47(16):4683-91. PubMed ID: 18373353
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Identification, synthesis, and characterization of new glycogen phosphorylase inhibitors binding to the allosteric AMP site.
    Kristiansen M; Andersen B; Iversen LF; Westergaard N
    J Med Chem; 2004 Jul; 47(14):3537-45. PubMed ID: 15214781
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Allosteric inhibition of glycogen phosphorylase a by the potential antidiabetic drug 3-isopropyl 4-(2-chlorophenyl)-1,4-dihydro-1-ethyl-2-methyl-pyridine-3,5,6-tricarbo xylate.
    Oikonomakos NG; Tsitsanou KE; Zographos SE; Skamnaki VT; Goldmann S; Bischoff H
    Protein Sci; 1999 Oct; 8(10):1930-45. PubMed ID: 10548038
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Glycogen phosphorylase inhibitors: a free energy perturbation analysis of glucopyranose spirohydantoin analogues.
    Archontis G; Watson KA; Xie Q; Andreou G; Chrysina ED; Zographos SE; Oikonomakos NG; Karplus M
    Proteins; 2005 Dec; 61(4):984-98. PubMed ID: 16245298
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Modeling aided design of potent glycogen phosphorylase inhibitors.
    Deng Q; Lu Z; Bohn J; Ellsworth KP; Myers RW; Geissler WM; Harris G; Willoughby CA; Chapman K; McKeever B; Mosley R
    J Mol Graph Model; 2005 Apr; 23(5):457-64. PubMed ID: 15781188
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Crystallographic and computational studies on 4-phenyl-N-(beta-D-glucopyranosyl)-1H-1,2,3-triazole-1-acetamide, an inhibitor of glycogen phosphorylase: comparison with alpha-D-glucose, N-acetyl-beta-D-glucopyranosylamine and N-benzoyl-N'-beta-D-glucopyranosyl urea binding.
    Alexacou KM; Hayes JM; Tiraidis C; Zographos SE; Leonidas DD; Chrysina ED; Archontis G; Oikonomakos NG; Paul JV; Varghese B; Loganathan D
    Proteins; 2008 May; 71(3):1307-23. PubMed ID: 18041758
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Sourcing the affinity of flavonoids for the glycogen phosphorylase inhibitor site via crystallography, kinetics and QM/MM-PBSA binding studies: comparison of chrysin and flavopiridol.
    Tsitsanou KE; Hayes JM; Keramioti M; Mamais M; Oikonomakos NG; Kato A; Leonidas DD; Zographos SE
    Food Chem Toxicol; 2013 Nov; 61():14-27. PubMed ID: 23279842
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Advances in glycogen phosphorylase inhibitor design.
    Oikonomakos NG; Somsák L
    Curr Opin Investig Drugs; 2008 Apr; 9(4):379-95. PubMed ID: 18393105
    [TBL] [Abstract][Full Text] [Related]  

  • 9. 1-(3-Deoxy-3-fluoro-beta-d-glucopyranosyl) pyrimidine derivatives as inhibitors of glycogen phosphorylase b: Kinetic, crystallographic and modelling studies.
    Tsirkone VG; Tsoukala E; Lamprakis C; Manta S; Hayes JM; Skamnaki VT; Drakou C; Zographos SE; Komiotis D; Leonidas DD
    Bioorg Med Chem; 2010 May; 18(10):3413-25. PubMed ID: 20430629
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Discovering benzamide derivatives as glycogen phosphorylase inhibitors and their binding site at the enzyme.
    Chen L; Li H; Liu J; Zhang L; Liu H; Jiang H
    Bioorg Med Chem; 2007 Nov; 15(21):6763-74. PubMed ID: 17719791
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Naturally occurring pentacyclic triterpenes as inhibitors of glycogen phosphorylase: synthesis, structure-activity relationships, and X-ray crystallographic studies.
    Wen X; Sun H; Liu J; Cheng K; Zhang P; Zhang L; Hao J; Zhang L; Ni P; Zographos SE; Leonidas DD; Alexacou KM; Gimisis T; Hayes JM; Oikonomakos NG
    J Med Chem; 2008 Jun; 51(12):3540-54. PubMed ID: 18517260
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The binding of β-d-glucopyranosyl-thiosemicarbazone derivatives to glycogen phosphorylase: A new class of inhibitors.
    Alexacou KM; Tenchiu Deleanu AC; Chrysina ED; Charavgi MD; Kostas ID; Zographos SE; Oikonomakos NG; Leonidas DD
    Bioorg Med Chem; 2010 Nov; 18(22):7911-22. PubMed ID: 20947361
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Kinetic and crystallographic studies of glucopyranose spirohydantoin and glucopyranosylamine analogs inhibitors of glycogen phosphorylase.
    Watson KA; Chrysina ED; Tsitsanou KE; Zographos SE; Archontis G; Fleet GW; Oikonomakos NG
    Proteins; 2005 Dec; 61(4):966-83. PubMed ID: 16222658
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Think twice: understanding the high potency of bis(phenyl)methane inhibitors of thrombin.
    Baum B; Muley L; Heine A; Smolinski M; Hangauer D; Klebe G
    J Mol Biol; 2009 Aug; 391(3):552-64. PubMed ID: 19520086
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Thermodynamic characterization of the binding of tetrahydropterins to phenylalanine hydroxylase.
    Pey AL; Thórólfsson M; Teigen K; Ugarte M; Martínez A
    J Am Chem Soc; 2004 Oct; 126(42):13670-8. PubMed ID: 15493924
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Isothermal titration microcalorimetric studies for the binding of octenoyl-CoA to medium chain acyl-CoA dehydrogenase.
    Srivastava DK; Wang S; Peterson KL
    Biochemistry; 1997 May; 36(21):6359-66. PubMed ID: 9174351
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Anthranilimide based glycogen phosphorylase inhibitors for the treatment of type 2 diabetes. Part 3: X-ray crystallographic characterization, core and urea optimization and in vivo efficacy.
    Thomson SA; Banker P; Bickett DM; Boucheron JA; Carter HL; Clancy DC; Cooper JP; Dickerson SH; Garrido DM; Nolte RT; Peat AJ; Sheckler LR; Sparks SM; Tavares FX; Wang L; Wang TY; Weiel JE
    Bioorg Med Chem Lett; 2009 Feb; 19(4):1177-82. PubMed ID: 19138846
    [TBL] [Abstract][Full Text] [Related]  

  • 18. An EPSP synthase inhibitor joining shikimate 3-phosphate with glyphosate: synthesis and ligand binding studies.
    Marzabadi MR; Gruys KJ; Pansegrau PD; Walker MC; Yuen HK; Sikorski JA
    Biochemistry; 1996 Apr; 35(13):4199-210. PubMed ID: 8672456
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Structural and thermodynamic study on aldose reductase: nitro-substituted inhibitors with strong enthalpic binding contribution.
    Steuber H; Heine A; Klebe G
    J Mol Biol; 2007 May; 368(3):618-38. PubMed ID: 17368668
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Interaction of pyridine nucleotide substrates with Escherichia coli dihydrodipicolinate reductase: thermodynamic and structural analysis of binary complexes.
    Reddy SG; Scapin G; Blanchard JS
    Biochemistry; 1996 Oct; 35(41):13294-302. PubMed ID: 8873595
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 19.