BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

212 related articles for article (PubMed ID: 18378693)

  • 1. Phospholipase Cgamma2 modulates integrin signaling in the osteoclast by affecting the localization and activation of Src kinase.
    Epple H; Cremasco V; Zhang K; Mao D; Longmore GD; Faccio R
    Mol Cell Biol; 2008 Jun; 28(11):3610-22. PubMed ID: 18378693
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Integrin alpha2beta1 induces phosphorylation-dependent and phosphorylation-independent activation of phospholipase Cgamma2 in platelets: role of Src kinase and Rac GTPase.
    Guidetti GF; Bernardi B; Consonni A; Rizzo P; Gruppi C; Balduini C; Torti M
    J Thromb Haemost; 2009 Jul; 7(7):1200-6. PubMed ID: 19422462
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The proline-rich tyrosine kinase Pyk2 regulates platelet integrin αIIbβ3 outside-in signaling.
    Cipolla L; Consonni A; Guidetti G; Canobbio I; Okigaki M; Falasca M; Ciraolo E; Hirsch E; Balduini C; Torti M
    J Thromb Haemost; 2013 Feb; 11(2):345-56. PubMed ID: 23216754
    [TBL] [Abstract][Full Text] [Related]  

  • 4. PYK2 in osteoclasts is an adhesion kinase, localized in the sealing zone, activated by ligation of alpha(v)beta3 integrin, and phosphorylated by src kinase.
    Duong LT; Lakkakorpi PT; Nakamura I; Machwate M; Nagy RM; Rodan GA
    J Clin Invest; 1998 Sep; 102(5):881-92. PubMed ID: 9727056
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Evidence that activation of ASIC1a by acidosis increases osteoclast migration and adhesion by modulating integrin/Pyk2/Src signaling pathway.
    Li X; Ye JX; Xu MH; Zhao MD; Yuan FL
    Osteoporos Int; 2017 Jul; 28(7):2221-2231. PubMed ID: 28462470
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Dynamic changes in the osteoclast cytoskeleton in response to growth factors and cell attachment are controlled by beta3 integrin.
    Faccio R; Novack DV; Zallone A; Ross FP; Teitelbaum SL
    J Cell Biol; 2003 Aug; 162(3):499-509. PubMed ID: 12900398
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Convergence of alpha(v)beta(3) integrin- and macrophage colony stimulating factor-mediated signals on phospholipase Cgamma in prefusion osteoclasts.
    Nakamura I; Lipfert L; Rodan GA; Le T Duong
    J Cell Biol; 2001 Jan; 152(2):361-73. PubMed ID: 11266452
    [TBL] [Abstract][Full Text] [Related]  

  • 8. PYK2 autophosphorylation, but not kinase activity, is necessary for adhesion-induced association with c-Src, osteoclast spreading, and bone resorption.
    Lakkakorpi PT; Bett AJ; Lipfert L; Rodan GA; Duong LT
    J Biol Chem; 2003 Mar; 278(13):11502-12. PubMed ID: 12514172
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Abnormal localisation and hyperclustering of (alpha)(V)(beta)(3) integrins and associated proteins in Src-deficient or tyrphostin A9-treated osteoclasts.
    Lakkakorpi PT; Nakamura I; Young M; Lipfert L; Rodan GA; Duong LT
    J Cell Sci; 2001 Jan; 114(Pt 1):149-160. PubMed ID: 11112699
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Src kinase activity is essential for osteoclast function.
    Miyazaki T; Sanjay A; Neff L; Tanaka S; Horne WC; Baron R
    J Biol Chem; 2004 Apr; 279(17):17660-6. PubMed ID: 14739300
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Myristoleic acid inhibits osteoclast formation and bone resorption by suppressing the RANKL activation of Src and Pyk2.
    Kwon JO; Jin WJ; Kim B; Kim HH; Lee ZH
    Eur J Pharmacol; 2015 Dec; 768():189-98. PubMed ID: 26528796
    [TBL] [Abstract][Full Text] [Related]  

  • 12. An osteoclastic protein-tyrosine phosphatase regulates the β3-integrin, syk, and shp1 signaling through respective src-dependent phosphorylation in osteoclasts.
    Lau KH; Stiffel V; Amoui M
    Am J Physiol Cell Physiol; 2012 Jun; 302(11):C1676-86. PubMed ID: 22460711
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Phospholipase Cγ2 is required for basal but not oestrogen deficiency-induced bone resorption.
    Kertész Z; Gyori D; Körmendi S; Fekete T; Kis-Tóth K; Jakus Z; Schett G; Rajnavölgyi E; Dobó-Nagy C; Mócsai A
    Eur J Clin Invest; 2012 Jan; 42(1):49-60. PubMed ID: 21749368
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Osteoprotegerin induces podosome disassembly in osteoclasts through calcium, ERK, and p38 MAPK signaling pathways.
    Zhao H; Liu X; Zou H; Dai N; Yao L; Gao Q; Liu W; Gu J; Yuan Y; Bian J; Liu Z
    Cytokine; 2015 Feb; 71(2):199-206. PubMed ID: 25461399
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Inhibition of osteoclast function by adenovirus expressing antisense protein-tyrosine kinase 2.
    Duong LT; Nakamura I; Lakkakorpi PT; Lipfert L; Bett AJ; Rodan GA
    J Biol Chem; 2001 Mar; 276(10):7484-92. PubMed ID: 11102447
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Inhibition of osteoclast activation by phloretin through disturbing αvβ3 integrin-c-Src pathway.
    Lee EJ; Kim JL; Gong JH; Park SH; Kang YH
    Biomed Res Int; 2015; 2015():680145. PubMed ID: 25834823
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Integrin-mediated signaling in the regulation of osteoclast adhesion and activation.
    Duong LT; Rodan GA
    Front Biosci; 1998 Aug; 3():d757-68. PubMed ID: 9682033
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Calcitonin induces podosome disassembly and detachment of osteoclasts by modulating Pyk2 and Src activities.
    Shyu JF; Shih C; Tseng CY; Lin CH; Sun DT; Liu HT; Tsung HC; Chen TH; Lu RB
    Bone; 2007 May; 40(5):1329-42. PubMed ID: 17321230
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Critical role of phospholipase Cgamma2 in integrin and Fc receptor-mediated neutrophil functions and the effector phase of autoimmune arthritis.
    Jakus Z; Simon E; Frommhold D; Sperandio M; Mócsai A
    J Exp Med; 2009 Mar; 206(3):577-93. PubMed ID: 19273622
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Dynamin forms a Src kinase-sensitive complex with Cbl and regulates podosomes and osteoclast activity.
    Bruzzaniti A; Neff L; Sanjay A; Horne WC; De Camilli P; Baron R
    Mol Biol Cell; 2005 Jul; 16(7):3301-13. PubMed ID: 15872089
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.