BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

146 related articles for article (PubMed ID: 18384750)

  • 1. Sumoylation of Smad3 stimulates its nuclear export during PIASy-mediated suppression of TGF-beta signaling.
    Imoto S; Ohbayashi N; Ikeda O; Kamitani S; Muromoto R; Sekine Y; Matsuda T
    Biochem Biophys Res Commun; 2008 May; 370(2):359-65. PubMed ID: 18384750
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The RING domain of PIASy is involved in the suppression of bone morphogenetic protein-signaling pathway.
    Imoto S; Sugiyama K; Yamamoto T; Matsuda T
    Biochem Biophys Res Commun; 2004 Jun; 319(1):275-82. PubMed ID: 15158472
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Roles for lysine residues of the MH2 domain of Smad3 in transforming growth factor-beta signaling.
    Imoto S; Sugiyama K; Sekine Y; Matsuda T
    FEBS Lett; 2005 May; 579(13):2853-62. PubMed ID: 15907489
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Regulation of transforming growth factor-beta signaling by protein inhibitor of activated STAT, PIASy through Smad3.
    Imoto S; Sugiyama K; Muromoto R; Sato N; Yamamoto T; Matsuda T
    J Biol Chem; 2003 Sep; 278(36):34253-8. PubMed ID: 12815042
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Geldanamycin inhibits TGF-beta signaling through induction of Hsp70.
    Yun CH; Yoon SY; Nguyen TT; Cho HY; Kim TH; Kim ST; Kim BC; Hong YS; Kim SJ; Lee HJ
    Arch Biochem Biophys; 2010 Mar; 495(1):8-13. PubMed ID: 19995547
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Antagonism of transforming growth factor-Beta signaling inhibits fibrosis-related genes.
    Liu XJ; Ruan CM; Gong XF; Li XZ; Wang HL; Wang MW; Yin JQ
    Biotechnol Lett; 2005 Oct; 27(20):1609-15. PubMed ID: 16245182
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A tale of two proteins: differential roles and regulation of Smad2 and Smad3 in TGF-beta signaling.
    Brown KA; Pietenpol JA; Moses HL
    J Cell Biochem; 2007 May; 101(1):9-33. PubMed ID: 17340614
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Clusterin, a novel modulator of TGF-beta signaling, is involved in Smad2/3 stability.
    Lee KB; Jeon JH; Choi I; Kwon OY; Yu K; You KH
    Biochem Biophys Res Commun; 2008 Feb; 366(4):905-9. PubMed ID: 18082619
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Requirement of Smad3 for mast cell growth.
    Funaba M; Nakaya K; Ikeda T; Murakami M; Tsuchida K; Sugino H
    Cell Immunol; 2006 Mar; 240(1):47-52. PubMed ID: 16839529
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Genetic alterations of the TGF-beta signaling pathway in colorectal cancer cell lines: a novel mutation in Smad3 associated with the inactivation of TGF-beta-induced transcriptional activation.
    Ku JL; Park SH; Yoon KA; Shin YK; Kim KH; Choi JS; Kang HC; Kim IJ; Han IO; Park JG
    Cancer Lett; 2007 Mar; 247(2):283-92. PubMed ID: 16828225
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Large hepatitis delta antigen modulates transforming growth factor-beta signaling cascades: implication of hepatitis delta virus-induced liver fibrosis.
    Choi SH; Jeong SH; Hwang SB
    Gastroenterology; 2007 Jan; 132(1):343-57. PubMed ID: 17241884
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Nuclear translocation of SMAD3 may enhance the TGF-beta/SMADS pathway in high glucose circumstances.
    Li Q; Ye F; Shi Y; Zhang L; Wang W; Tu Z; Qiu J; Wang J; Li S; Bu H; Li Y
    Transplant Proc; 2006 Sep; 38(7):2158-60. PubMed ID: 16980030
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Smad3 is key to TGF-beta-mediated epithelial-to-mesenchymal transition, fibrosis, tumor suppression and metastasis.
    Roberts AB; Tian F; Byfield SD; Stuelten C; Ooshima A; Saika S; Flanders KC
    Cytokine Growth Factor Rev; 2006; 17(1-2):19-27. PubMed ID: 16290023
    [TBL] [Abstract][Full Text] [Related]  

  • 14. TGF-beta and cancer: is Smad3 a repressor of hTERT gene?
    Li H; Xu D; Toh BH; Liu JP
    Cell Res; 2006 Feb; 16(2):169-73. PubMed ID: 16474430
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Repression of E1AF transcriptional activity by sumoylation and PIASy.
    Nishida T; Terashima M; Fukami K; Yamada Y
    Biochem Biophys Res Commun; 2007 Aug; 360(1):226-32. PubMed ID: 17585876
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Chromatin immunoprecipitation on microarray analysis of Smad2/3 binding sites reveals roles of ETS1 and TFAP2A in transforming growth factor beta signaling.
    Koinuma D; Tsutsumi S; Kamimura N; Taniguchi H; Miyazawa K; Sunamura M; Imamura T; Miyazono K; Aburatani H
    Mol Cell Biol; 2009 Jan; 29(1):172-86. PubMed ID: 18955504
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Smad2 and Smad3 phosphorylated at both linker and COOH-terminal regions transmit malignant TGF-beta signal in later stages of human colorectal cancer.
    Matsuzaki K; Kitano C; Murata M; Sekimoto G; Yoshida K; Uemura Y; Seki T; Taketani S; Fujisawa J; Okazaki K
    Cancer Res; 2009 Jul; 69(13):5321-30. PubMed ID: 19531654
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Statin suppresses apoptosis in osteoblastic cells: role of transforming growth factor-beta-Smad3 pathway.
    Kaji H; Naito J; Inoue Y; Sowa H; Sugimoto T; Chihara K
    Horm Metab Res; 2008 Nov; 40(11):746-51. PubMed ID: 18622892
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The mechanism of nuclear export of Smad3 involves exportin 4 and Ran.
    Kurisaki A; Kurisaki K; Kowanetz M; Sugino H; Yoneda Y; Heldin CH; Moustakas A
    Mol Cell Biol; 2006 Feb; 26(4):1318-32. PubMed ID: 16449645
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mechanisms of action of TGF-beta in cancer: evidence for Smad3 as a repressor of the hTERT gene.
    Li H; Liu JP
    Ann N Y Acad Sci; 2007 Oct; 1114():56-68. PubMed ID: 17934056
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.