BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

867 related articles for article (PubMed ID: 18389514)

  • 21. Prodrugs of HIV protease inhibitors-saquinavir, indinavir and nelfinavir-derived from diglycerides or amino acids: synthesis, stability and anti-HIV activity.
    Gaucher B; Rouquayrol M; Roche D; Greiner J; Aubertin AM; Vierling P
    Org Biomol Chem; 2004 Feb; 2(3):345-57. PubMed ID: 14747863
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Self-assembled drug delivery systems. Part 4. In vitro/in vivo studies of the self-assemblies of cholesteryl-phosphonyl zidovudine.
    Jin Y; Xing L; Tian Y; Li M; Gao C; Du L; Dong J; Chen H
    Int J Pharm; 2009 Oct; 381(1):40-8. PubMed ID: 19646518
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Synthesis and in vitro activity of long-chain 5'-O-[(alkoxycarbonyl)phosphinyl]-3'-azido-3'-deoxythymidines against wild-type and AZT- and foscarnet-resistant strains of HIV-1.
    Rosowsky A; Fu H; Pai N; Mellors J; Richman DD; Hostetler KY
    J Med Chem; 1997 Aug; 40(16):2482-90. PubMed ID: 9258355
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Design and discovery of a novel dipeptidyl-peptidase IV (CD26)-based prodrug approach.
    García-Aparicio C; Bonache MC; De Meester I; San-Félix A; Balzarini J; Camarasa MJ; Velazquez S
    J Med Chem; 2006 Aug; 49(17):5339-51. PubMed ID: 16913724
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Design, synthesis, and evaluation of tripeptidic promoieties targeting the intestinal peptide transporter hPEPT1.
    Thorn K; Andersen R; Christensen J; Jakobsen P; Nielsen CU; Steffansen B; Begtrup M
    ChemMedChem; 2007 Apr; 2(4):479-87. PubMed ID: 17407174
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Probing the mechanism of action and decomposition of amino acid phosphomonoester amidates of antiviral nucleoside prodrugs.
    McIntee EJ; Remmel RP; Schinazi RF; Abraham TW; Wagner CR
    J Med Chem; 1997 Oct; 40(21):3323-31. PubMed ID: 9341906
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Pharmacokinetics of novel dipeptide ester prodrugs of acyclovir after oral administration: intestinal absorption and liver metabolism.
    Anand BS; Katragadda S; Mitra AK
    J Pharmacol Exp Ther; 2004 Nov; 311(2):659-67. PubMed ID: 15226381
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Conformational restrictions in ligand binding to the human intestinal di-/tripeptide transporter: implications for design of hPEPT1 targeted prodrugs.
    Våbenø J; Nielsen CU; Steffansen B; Lejon T; Sylte I; Jørgensen FS; Luthman K
    Bioorg Med Chem; 2005 Mar; 13(6):1977-88. PubMed ID: 15727852
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Design of new mononucleotide prodrugs: aryl (SATE) phosphotriester derivatives.
    Peyrottes S; Schlienger N; Beltran T; Lefebvre I; Pompon A; Gosselin G; Aubertin AM; Imbach JL; Périgaud C
    Nucleosides Nucleotides Nucleic Acids; 2001; 20(4-7):315-21. PubMed ID: 11563043
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Derivatives of melphalan designed to enhance drug accumulation in cancer cells.
    Kupczyk-Subotkowska L; Tamura K; Pal D; Sakaeda T; Siahaan TJ; Stella VJ; Borchardt RT
    J Drug Target; 1997; 4(6):359-70. PubMed ID: 9239576
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Kinetics of degradation and oil solubility of ester prodrugs of a model dipeptide (Gly-Phe).
    Larsen SW; Ankersen M; Larsen C
    Eur J Pharm Sci; 2004 Aug; 22(5):399-408. PubMed ID: 15265509
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Serine side chain-linked peptidomimetic conjugates of cyclic HPMPC and HPMPA: synthesis and interaction with hPEPT1.
    Peterson LW; Sala-Rabanal M; Krylov IS; Serpi M; Kashemirov BA; McKenna CE
    Mol Pharm; 2010 Dec; 7(6):2349-61. PubMed ID: 20929265
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Synthesis and antiviral activity of amino acid carbamate derivatives of AZT.
    Chang SL; Griesgraber G; Abraham TW; Garg T; Song H; Zimmerman CL; Wagner CR
    Nucleosides Nucleotides Nucleic Acids; 2000; 19(1-2):87-100. PubMed ID: 10772704
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Synthesis of poly(ethylene glycol)-based saquinavir prodrug conjugates and assessment of release and anti-HIV-1 bioactivity using a novel protease inhibition assay.
    Gunaseelan S; Debrah O; Wan L; Leibowitz MJ; Rabson AB; Stein S; Sinko PJ
    Bioconjug Chem; 2004; 15(6):1322-33. PubMed ID: 15546199
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Synthesis, anti-HIV activity, and stability studies of 5'-phosphorofluoridate derivatives of AZT.
    Egron D; Arzumanov AA; Dyatkina NB; Aubertin AM; Imbach JL; Gosselin G; Krayevsky A; Périgaud C
    Bioorg Chem; 2001 Dec; 29(6):333-44. PubMed ID: 11846432
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Application of enzymatically stable dipeptides for enhancement of intestinal permeability. Synthesis and in vitro evaluation of dipeptide-coupled compounds.
    Friedrichsen GM; Jakobsen P; Taub M; Begtrup M
    Bioorg Med Chem; 2001 Oct; 9(10):2625-32. PubMed ID: 11557350
    [TBL] [Abstract][Full Text] [Related]  

  • 37. In vitro anti-hepatitis B virus activities of 5"-O-myristoyl analogue derivatives of 3"-fluoro-2",3"-dideoxythymidine (FLT) and 3"-azido-2",3"-dideoxythymidine (AZT).
    Parang K; Wiebe LI; Knaus EE; Huang JS; Tyrrell DL
    J Pharm Pharm Sci; 1998; 1(3):108-14. PubMed ID: 10948398
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Dipeptide model prodrugs for the intestinal oligopeptide transporter. Affinity for and transport via hPepT1 in the human intestinal Caco-2 cell line.
    Nielsen CU; Andersen R; Brodin B; Frokjaer S; Taub ME; Steffansen B
    J Control Release; 2001 Sep; 76(1-2):129-38. PubMed ID: 11532319
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Phenyl phosphotriester derivatives of AZT: variations upon the SATE moiety.
    Villard AL; Coussot G; Lefebvre I; Augustijns P; Aubertin AM; Gosselin G; Peyrottes S; Périgaud C
    Bioorg Med Chem; 2008 Aug; 16(15):7321-9. PubMed ID: 18585917
    [TBL] [Abstract][Full Text] [Related]  

  • 40. In vitro evaluation of N-methyl amide tripeptidomimetics as substrates for the human intestinal di-/tri-peptide transporter hPEPT1.
    Andersen R; Nielsen CU; Begtrup M; Jørgensen FS; Brodin B; Frokjaer S; Steffansen B
    Eur J Pharm Sci; 2006 Jul; 28(4):325-35. PubMed ID: 16713701
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 44.