These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

110 related articles for article (PubMed ID: 18393446)

  • 41. 2-Alkylamino- and alkoxy-substituted 2-amino-1,3,4-oxadiazoles-O-Alkyl benzohydroxamate esters replacements retain the desired inhibition and selectivity against MEK (MAP ERK kinase).
    Warmus JS; Flamme C; Zhang LY; Barrett S; Bridges A; Chen H; Gowan R; Kaufman M; Sebolt-Leopold J; Leopold W; Merriman R; Ohren J; Pavlovsky A; Przybranowski S; Tecle H; Valik H; Whitehead C; Zhang E
    Bioorg Med Chem Lett; 2008 Dec; 18(23):6171-4. PubMed ID: 18951019
    [TBL] [Abstract][Full Text] [Related]  

  • 42. MALDI-TOF mass-spectrometry-based versatile method for the characterization of protein kinases.
    Kondo N; Nishimura S
    Chemistry; 2009; 15(6):1413-21. PubMed ID: 19115309
    [TBL] [Abstract][Full Text] [Related]  

  • 43. Identification of potent, selective protein kinase C inhibitors based on a phorbol skeleton.
    Yamatsugu K; Motoki R; Kanai M; Shibasaki M
    Chem Asian J; 2006 Sep; 1(3):314-21. PubMed ID: 17441066
    [TBL] [Abstract][Full Text] [Related]  

  • 44. Role of RAF/MEK/ERK pathway, p-STAT-3 and Mcl-1 in sorafenib activity in human pancreatic cancer cell lines.
    Ulivi P; Arienti C; Amadori D; Fabbri F; Carloni S; Tesei A; Vannini I; Silvestrini R; Zoli W
    J Cell Physiol; 2009 Jul; 220(1):214-21. PubMed ID: 19288493
    [TBL] [Abstract][Full Text] [Related]  

  • 45. Regulation of Ca2+/calmodulin-dependent protein kinase II catalysis by N-methyl-D-aspartate receptor subunit 2B.
    Pradeep KK; Cheriyan J; Suma Priya SD; Rajeevkumar R; Mayadevi M; Praseeda M; Omkumar RV
    Biochem J; 2009 Apr; 419(1):123-32, 4 p following 132. PubMed ID: 19086921
    [TBL] [Abstract][Full Text] [Related]  

  • 46. Design, synthesis and biological evaluation of cobalt(II)-Schiff base complexes as ATP-noncompetitive MEK1 inhibitors.
    Li H; Xi D; Niu Y; Wang C; Xu F; Liang L; Xu P
    J Inorg Biochem; 2019 Jun; 195():174-181. PubMed ID: 30954694
    [TBL] [Abstract][Full Text] [Related]  

  • 47. Identification of isothiazole-4-carboxamidines derivatives as a novel class of allosteric MEK1 inhibitors.
    El Abdellaoui H; Varaprasad CV; Barawkar D; Chakravarty S; Maderna A; Tam R; Chen H; Allan M; Wu JZ; Appleby T; Yan S; Zhang W; Lang S; Yao N; Hamatake R; Hong Z
    Bioorg Med Chem Lett; 2006 Nov; 16(21):5561-6. PubMed ID: 16934458
    [TBL] [Abstract][Full Text] [Related]  

  • 48. Examining Ligand-Based Stabilization of Proteins in Cells with MEK1 Kinase Inhibitors.
    Auld DS; Davis CA; Jimenez M; Knight S; Orme JP
    Assay Drug Dev Technol; 2015 Jun; 13(5):266-76. PubMed ID: 26107610
    [TBL] [Abstract][Full Text] [Related]  

  • 49. Calculating the probability of detection for inhibitors in enzymatic or binding reactions in high-throughput screening.
    Buxser S; Vroegop S
    Anal Biochem; 2005 May; 340(1):1-13. PubMed ID: 15802124
    [TBL] [Abstract][Full Text] [Related]  

  • 50. A general strategy for creating "inactive-conformation" abl inhibitors.
    Okram B; Nagle A; Adrián FJ; Lee C; Ren P; Wang X; Sim T; Xie Y; Wang X; Xia G; Spraggon G; Warmuth M; Liu Y; Gray NS
    Chem Biol; 2006 Jul; 13(7):779-86. PubMed ID: 16873026
    [TBL] [Abstract][Full Text] [Related]  

  • 51. Defining balanced conditions for inhibitor screening assays that target bisubstrate enzymes.
    Yang J; Copeland RA; Lai Z
    J Biomol Screen; 2009 Feb; 14(2):111-20. PubMed ID: 19196704
    [TBL] [Abstract][Full Text] [Related]  

  • 52. Synthesis and evaluation of 2-(1H-indol-3-yl)-4-phenylquinolines as inhibitors of cholesterol esterase.
    Muscia GC; Hautmann S; Buldain GY; Asís SE; Gütschow M
    Bioorg Med Chem Lett; 2014 Mar; 24(6):1545-9. PubMed ID: 24556381
    [TBL] [Abstract][Full Text] [Related]  

  • 53. The discovery of 2-amino-3,5-diarylbenzamide inhibitors of IKK-alpha and IKK-beta kinases.
    Christopher JA; Avitabile BG; Bamborough P; Champigny AC; Cutler GJ; Dyos SL; Grace KG; Kerns JK; Kitson JD; Mellor GW; Morey JV; Morse MA; O'Malley CF; Patel CB; Probst N; Rumsey W; Smith CA; Wilson MJ
    Bioorg Med Chem Lett; 2007 Jul; 17(14):3972-7. PubMed ID: 17502144
    [TBL] [Abstract][Full Text] [Related]  

  • 54. ATP competitive inhibitors of D-alanine-D-alanine ligase based on protein kinase inhibitor scaffolds.
    Triola G; Wetzel S; Ellinger B; Koch MA; Hübel K; Rauh D; Waldmann H
    Bioorg Med Chem; 2009 Feb; 17(3):1079-87. PubMed ID: 18321716
    [TBL] [Abstract][Full Text] [Related]  

  • 55. Tight binding inhibitors of N-acyl amino sugar and N-acyl amino acid deacetylases.
    Xu C; Hall R; Cummings J; Raushel FM
    J Am Chem Soc; 2006 Apr; 128(13):4244-5. PubMed ID: 16568996
    [TBL] [Abstract][Full Text] [Related]  

  • 56. The role of alkyl chain length in the inhibitory effect n-alkyl xanthates on mushroom tyrosinase activities.
    Saboury AA; Alijanianzadeh M; Mansoori-Torshizi H
    Acta Biochim Pol; 2007; 54(1):183-91. PubMed ID: 17369881
    [TBL] [Abstract][Full Text] [Related]  

  • 57. Discovery of 3-hydroxy-4-carboxyalkylamidino-5-arylamino-isothiazoles as potent MEK1 inhibitors.
    Varaprasad CV; Barawkar D; El Abdellaoui H; Chakravarty S; Allan M; Chen H; Zhang W; Wu JZ; Tam R; Hamatake R; Lang S; Hong Z
    Bioorg Med Chem Lett; 2006 Aug; 16(15):3975-80. PubMed ID: 16725322
    [TBL] [Abstract][Full Text] [Related]  

  • 58. Detection of competitive enzyme inhibition with end point progress curve data.
    Gutiérrez OA; Danielson UH
    Anal Biochem; 2006 Nov; 358(1):11-9. PubMed ID: 16978578
    [TBL] [Abstract][Full Text] [Related]  

  • 59. Pyrimidine-based inhibitors of CaMKIIdelta.
    Mavunkel B; Xu YJ; Goyal B; Lim D; Lu Q; Chen Z; Wang DX; Higaki J; Chakraborty I; Liclican A; Sideris S; Laney M; Delling U; Catalano R; Higgins LS; Wang H; Wang J; Feng Y; Dugar S; Levy DE
    Bioorg Med Chem Lett; 2008 Apr; 18(7):2404-8. PubMed ID: 18334293
    [TBL] [Abstract][Full Text] [Related]  

  • 60. Discovery of picomolar slow tight-binding inhibitors of alpha-fucosidase.
    Chang CF; Ho CW; Wu CY; Chao TA; Wong CH; Lin CH
    Chem Biol; 2004 Sep; 11(9):1301-6. PubMed ID: 15380190
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 6.