BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

146 related articles for article (PubMed ID: 18394010)

  • 1. Hypoxia-inducible factor-2alpha: effect on radiation sensitivity and differential regulation by an mTOR inhibitor.
    Bhatt RS; Landis DM; Zimmer M; Torregrossa J; Chen S; Sukhatme VP; Iliopoulos O; Balk S; Bubley GJ
    BJU Int; 2008 Aug; 102(3):358-63. PubMed ID: 18394010
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Reciprocal regulation of hypoxia-inducible factor 2α and GLI1 expression associated with the radioresistance of renal cell carcinoma.
    Zhou J; Wu K; Gao D; Zhu G; Wu D; Wang X; Chen Y; Du Y; Song W; Ma Z; Authement C; Saha D; Hsieh JT; He D
    Int J Radiat Oncol Biol Phys; 2014 Nov; 90(4):942-51. PubMed ID: 25585786
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Evaluating rational non-cross-resistant combination therapy in advanced clear cell renal cell carcinoma: combined mTOR and AKT inhibitor therapy.
    Holland WS; Tepper CG; Pietri JE; Chinn DC; Gandara DR; Mack PC; Lara PN
    Cancer Chemother Pharmacol; 2012 Jan; 69(1):185-94. PubMed ID: 21644050
    [TBL] [Abstract][Full Text] [Related]  

  • 4. HIF2α acts as an mTORC1 activator through the amino acid carrier SLC7A5.
    Elorza A; Soro-Arnáiz I; Meléndez-Rodríguez F; Rodríguez-Vaello V; Marsboom G; de Cárcer G; Acosta-Iborra B; Albacete-Albacete L; Ordóñez A; Serrano-Oviedo L; Giménez-Bachs JM; Vara-Vega A; Salinas A; Sánchez-Prieto R; Martín del Río R; Sánchez-Madrid F; Malumbres M; Landázuri MO; Aragonés J
    Mol Cell; 2012 Dec; 48(5):681-91. PubMed ID: 23103253
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Up-regulation of hypoxia-inducible factor 2alpha in renal cell carcinoma associated with loss of Tsc-2 tumor suppressor gene.
    Liu MY; Poellinger L; Walker CL
    Cancer Res; 2003 May; 63(10):2675-80. PubMed ID: 12750296
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synergistic roles of p53 and HIF1α in human renal cell carcinoma-cell apoptosis responding to the inhibition of mTOR and MDM2 signaling pathways.
    Liu QJ; Shen HL; Lin J; Xu XH; Ji ZG; Han X; Shang DH; Yang PQ
    Drug Des Devel Ther; 2016; 10():745-55. PubMed ID: 26937175
    [TBL] [Abstract][Full Text] [Related]  

  • 7. PHGDH as a Key Enzyme for Serine Biosynthesis in HIF2α-Targeting Therapy for Renal Cell Carcinoma.
    Yoshino H; Nohata N; Miyamoto K; Yonemori M; Sakaguchi T; Sugita S; Itesako T; Kofuji S; Nakagawa M; Dahiya R; Enokida H
    Cancer Res; 2017 Nov; 77(22):6321-6329. PubMed ID: 28951458
    [TBL] [Abstract][Full Text] [Related]  

  • 8. mTOR in renal cell cancer: modulator of tumor biology and therapeutic target.
    Wysocki PJ
    Expert Rev Mol Diagn; 2009 Apr; 9(3):231-41. PubMed ID: 19379082
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The preclinical assessment of XL388, a mTOR kinase inhibitor, as a promising anti-renal cell carcinoma agent.
    Xiong Z; Zang Y; Zhong S; Zou L; Wu Y; Liu S; Fang Z; Shen Z; Ding Q; Chen S
    Oncotarget; 2017 May; 8(18):30151-30161. PubMed ID: 28404914
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Hypoxia-inducible factor-2alpha regulates the expression of TRAIL receptor DR5 in renal cancer cells.
    Mahajan S; Dammai V; Hsu T; Kraft AS
    Carcinogenesis; 2008 Sep; 29(9):1734-41. PubMed ID: 18544564
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Everolimus resistance in clear cell renal cell carcinoma: miRNA-101 and HIF-2α as molecular triggers?
    Nogueira I; Dias F; Morais M; Teixeira AL; Medeiros R
    Future Oncol; 2019 Jul; 15(20):2361-2370. PubMed ID: 31267758
    [No Abstract]   [Full Text] [Related]  

  • 12. Potential new therapy of Rapalink-1, a new generation mammalian target of rapamycin inhibitor, against sunitinib-resistant renal cell carcinoma.
    Kuroshima K; Yoshino H; Okamura S; Tsuruda M; Osako Y; Sakaguchi T; Sugita S; Tatarano S; Nakagawa M; Enokida H
    Cancer Sci; 2020 May; 111(5):1607-1618. PubMed ID: 32232883
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Pre-clinical evaluation of AZD-2014, a novel mTORC1/2 dual inhibitor, against renal cell carcinoma.
    Zheng B; Mao JH; Qian L; Zhu H; Gu DH; Pan XD; Yi F; Ji DM
    Cancer Lett; 2015 Feb; 357(2):468-75. PubMed ID: 25444920
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Effect of rapamycin, an mTOR inhibitor, on radiation sensitivity of lung cancer cells having different p53 gene status.
    Nagata Y; Takahashi A; Ohnishi K; Ota I; Ohnishi T; Tojo T; Taniguchi S
    Int J Oncol; 2010 Oct; 37(4):1001-10. PubMed ID: 20811722
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Norcantharidin counteracts acquired everolimus resistance in renal cell carcinoma by dual inhibition of mammalian target of rapamycin complex 1 and complex 2 pathways in Vitro.
    Chen X; Cai X; Zheng D; Huang X; Chen Y; Deng T; Mo L; Li H; Li J; Chen S
    Anticancer Drugs; 2022 Jan; 33(1):e94-e102. PubMed ID: 34261913
    [TBL] [Abstract][Full Text] [Related]  

  • 16. HIF2α is involved in the expansion of CXCR4-positive cancer stem-like cells in renal cell carcinoma.
    Micucci C; Matacchione G; Valli D; Orciari S; Catalano A
    Br J Cancer; 2015 Oct; 113(8):1178-85. PubMed ID: 26439684
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Loss of VHL and hypoxia provokes PAX2 up-regulation in clear cell renal cell carcinoma.
    Luu VD; Boysen G; Struckmann K; Casagrande S; von Teichman A; Wild PJ; Sulser T; Schraml P; Moch H
    Clin Cancer Res; 2009 May; 15(10):3297-304. PubMed ID: 19401348
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Hypoxia inducible factor (HIf1alpha and HIF2alpha) and carbonic anhydrase 9 (CA9) expression and response of head-neck cancer to hypofractionated and accelerated radiotherapy.
    Koukourakis MI; Giatromanolaki A; Danielidis V; Sivridis E
    Int J Radiat Biol; 2008 Jan; 84(1):47-52. PubMed ID: 17852557
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Opposite prognostic roles of HIF1α and HIF2α expressions in bone metastatic clear cell renal cell cancer.
    Szendrői A; Szász AM; Kardos M; Tőkés AM; Idan R; Szűcs M; Kulka J; Nyirády P; Szendrői M; Szállási Z; Győrffy B; Tímár J
    Oncotarget; 2016 Jul; 7(27):42086-42098. PubMed ID: 27244898
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Upstream signaling inhibition enhances rapamycin effect on growth of kidney cancer cells.
    Costa LJ; Gemmill RM; Drabkin HA
    Urology; 2007 Mar; 69(3):596-602. PubMed ID: 17382186
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.