These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

198 related articles for article (PubMed ID: 18400759)

  • 1. Sex-dependent effect of BAG1 in ameliorating motor deficits of Huntington disease transgenic mice.
    Orr AL; Huang S; Roberts MA; Reed JC; Li S; Li XJ
    J Biol Chem; 2008 Jun; 283(23):16027-36. PubMed ID: 18400759
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mutant huntingtin in glial cells exacerbates neurological symptoms of Huntington disease mice.
    Bradford J; Shin JY; Roberts M; Wang CE; Sheng G; Li S; Li XJ
    J Biol Chem; 2010 Apr; 285(14):10653-61. PubMed ID: 20145253
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The induction levels of heat shock protein 70 differentiate the vulnerabilities to mutant huntingtin among neuronal subtypes.
    Tagawa K; Marubuchi S; Qi ML; Enokido Y; Tamura T; Inagaki R; Murata M; Kanazawa I; Wanker EE; Okazawa H
    J Neurosci; 2007 Jan; 27(4):868-80. PubMed ID: 17251428
    [TBL] [Abstract][Full Text] [Related]  

  • 4. BAG1 modulates huntingtin toxicity, aggregation, degradation, and subcellular distribution.
    Sroka K; Voigt A; Deeg S; Reed JC; Schulz JB; Bähr M; Kermer P
    J Neurochem; 2009 Nov; 111(3):801-7. PubMed ID: 19712056
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Lack of interleukin-1 type 1 receptor enhances the accumulation of mutant huntingtin in the striatum and exacerbates the neurological phenotypes of Huntington's disease mice.
    Wang CE; Li S; Li XJ
    Mol Brain; 2010 Nov; 3():33. PubMed ID: 21044321
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Increased huntingtin protein length reduces the number of polyglutamine-induced gene expression changes in mouse models of Huntington's disease.
    Chan EY; Luthi-Carter R; Strand A; Solano SM; Hanson SA; DeJohn MM; Kooperberg C; Chase KO; DiFiglia M; Young AB; Leavitt BR; Cha JH; Aronin N; Hayden MR; Olson JM
    Hum Mol Genet; 2002 Aug; 11(17):1939-51. PubMed ID: 12165556
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Transducer of regulated CREB-binding proteins (TORCs) transcription and function is impaired in Huntington's disease.
    Chaturvedi RK; Hennessey T; Johri A; Tiwari SK; Mishra D; Agarwal S; Kim YS; Beal MF
    Hum Mol Genet; 2012 Aug; 21(15):3474-88. PubMed ID: 22589249
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Experimental mutagenesis of huntingtin to map cleavage sites: different outcomes in cell and mouse models.
    Tebbenkamp AT; Xu G; Siemienski ZB; Janus C; Fromholt SE; Brown HH; Swing D; Tessarollo L; Borchelt DR
    J Huntingtons Dis; 2014; 3(1):73-86. PubMed ID: 25062766
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Impaired heat shock response in cells expressing full-length polyglutamine-expanded huntingtin.
    Chafekar SM; Duennwald ML
    PLoS One; 2012; 7(5):e37929. PubMed ID: 22649566
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Characterization of huntingtin pathologic fragments in human Huntington disease, transgenic mice, and cell models.
    Schilling G; Klevytska A; Tebbenkamp AT; Juenemann K; Cooper J; Gonzales V; Slunt H; Poirer M; Ross CA; Borchelt DR
    J Neuropathol Exp Neurol; 2007 Apr; 66(4):313-20. PubMed ID: 17413322
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Polyglutamine length-dependent interaction of Hsp40 and Hsp70 family chaperones with truncated N-terminal huntingtin: their role in suppression of aggregation and cellular toxicity.
    Jana NR; Tanaka M; Wang Gh; Nukina N
    Hum Mol Genet; 2000 Aug; 9(13):2009-18. PubMed ID: 10942430
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Nuclear-targeting of mutant huntingtin fragments produces Huntington's disease-like phenotypes in transgenic mice.
    Schilling G; Savonenko AV; Klevytska A; Morton JL; Tucker SM; Poirier M; Gale A; Chan N; Gonzales V; Slunt HH; Coonfield ML; Jenkins NA; Copeland NG; Ross CA; Borchelt DR
    Hum Mol Genet; 2004 Aug; 13(15):1599-610. PubMed ID: 15190011
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Transgenic mice expressing caspase-6-derived N-terminal fragments of mutant huntingtin develop neurologic abnormalities with predominant cytoplasmic inclusion pathology composed largely of a smaller proteolytic derivative.
    Tebbenkamp AT; Green C; Xu G; Denovan-Wright EM; Rising AC; Fromholt SE; Brown HH; Swing D; Mandel RJ; Tessarollo L; Borchelt DR
    Hum Mol Genet; 2011 Jul; 20(14):2770-82. PubMed ID: 21515588
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Ectopic expression of the striatal-enriched GTPase Rhes elicits cerebellar degeneration and an ataxia phenotype in Huntington's disease.
    Swarnkar S; Chen Y; Pryor WM; Shahani N; Page DT; Subramaniam S
    Neurobiol Dis; 2015 Oct; 82():66-77. PubMed ID: 26048156
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Green tea (-)-epigallocatechin-gallate modulates early events in huntingtin misfolding and reduces toxicity in Huntington's disease models.
    Ehrnhoefer DE; Duennwald M; Markovic P; Wacker JL; Engemann S; Roark M; Legleiter J; Marsh JL; Thompson LM; Lindquist S; Muchowski PJ; Wanker EE
    Hum Mol Genet; 2006 Sep; 15(18):2743-51. PubMed ID: 16893904
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Electroconvulsive shock ameliorates disease processes and extends survival in huntingtin mutant mice.
    Mughal MR; Baharani A; Chigurupati S; Son TG; Chen E; Yang P; Okun E; Arumugam T; Chan SL; Mattson MP
    Hum Mol Genet; 2011 Feb; 20(4):659-69. PubMed ID: 21106706
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Neuroprotective effects of PPAR-γ agonist rosiglitazone in N171-82Q mouse model of Huntington's disease.
    Jin J; Albertz J; Guo Z; Peng Q; Rudow G; Troncoso JC; Ross CA; Duan W
    J Neurochem; 2013 May; 125(3):410-9. PubMed ID: 23373812
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Partial depletion of CREB-binding protein reduces life expectancy in a mouse model of Huntington disease.
    Klevytska AM; Tebbenkamp AT; Savonenko AV; Borchelt DR
    J Neuropathol Exp Neurol; 2010 Apr; 69(4):396-404. PubMed ID: 20448484
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Integration-independent Transgenic Huntington Disease Fragment Mouse Models Reveal Distinct Phenotypes and Life Span in Vivo.
    O'Brien R; DeGiacomo F; Holcomb J; Bonner A; Ring KL; Zhang N; Zafar K; Weiss A; Lager B; Schilling B; Gibson BW; Chen S; Kwak S; Ellerby LM
    J Biol Chem; 2015 Jul; 290(31):19287-306. PubMed ID: 26025364
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Neuroprotection by Hsp104 and Hsp27 in lentiviral-based rat models of Huntington's disease.
    Perrin V; Régulier E; Abbas-Terki T; Hassig R; Brouillet E; Aebischer P; Luthi-Carter R; Déglon N
    Mol Ther; 2007 May; 15(5):903-11. PubMed ID: 17375066
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.