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5. Lack of interleukin-1 type 1 receptor enhances the accumulation of mutant huntingtin in the striatum and exacerbates the neurological phenotypes of Huntington's disease mice. Wang CE; Li S; Li XJ Mol Brain; 2010 Nov; 3():33. PubMed ID: 21044321 [TBL] [Abstract][Full Text] [Related]
6. Increased huntingtin protein length reduces the number of polyglutamine-induced gene expression changes in mouse models of Huntington's disease. Chan EY; Luthi-Carter R; Strand A; Solano SM; Hanson SA; DeJohn MM; Kooperberg C; Chase KO; DiFiglia M; Young AB; Leavitt BR; Cha JH; Aronin N; Hayden MR; Olson JM Hum Mol Genet; 2002 Aug; 11(17):1939-51. PubMed ID: 12165556 [TBL] [Abstract][Full Text] [Related]
7. Transducer of regulated CREB-binding proteins (TORCs) transcription and function is impaired in Huntington's disease. Chaturvedi RK; Hennessey T; Johri A; Tiwari SK; Mishra D; Agarwal S; Kim YS; Beal MF Hum Mol Genet; 2012 Aug; 21(15):3474-88. PubMed ID: 22589249 [TBL] [Abstract][Full Text] [Related]
8. Experimental mutagenesis of huntingtin to map cleavage sites: different outcomes in cell and mouse models. Tebbenkamp AT; Xu G; Siemienski ZB; Janus C; Fromholt SE; Brown HH; Swing D; Tessarollo L; Borchelt DR J Huntingtons Dis; 2014; 3(1):73-86. PubMed ID: 25062766 [TBL] [Abstract][Full Text] [Related]
10. Characterization of huntingtin pathologic fragments in human Huntington disease, transgenic mice, and cell models. Schilling G; Klevytska A; Tebbenkamp AT; Juenemann K; Cooper J; Gonzales V; Slunt H; Poirer M; Ross CA; Borchelt DR J Neuropathol Exp Neurol; 2007 Apr; 66(4):313-20. PubMed ID: 17413322 [TBL] [Abstract][Full Text] [Related]
11. Polyglutamine length-dependent interaction of Hsp40 and Hsp70 family chaperones with truncated N-terminal huntingtin: their role in suppression of aggregation and cellular toxicity. Jana NR; Tanaka M; Wang Gh; Nukina N Hum Mol Genet; 2000 Aug; 9(13):2009-18. PubMed ID: 10942430 [TBL] [Abstract][Full Text] [Related]
12. Nuclear-targeting of mutant huntingtin fragments produces Huntington's disease-like phenotypes in transgenic mice. Schilling G; Savonenko AV; Klevytska A; Morton JL; Tucker SM; Poirier M; Gale A; Chan N; Gonzales V; Slunt HH; Coonfield ML; Jenkins NA; Copeland NG; Ross CA; Borchelt DR Hum Mol Genet; 2004 Aug; 13(15):1599-610. PubMed ID: 15190011 [TBL] [Abstract][Full Text] [Related]
13. Transgenic mice expressing caspase-6-derived N-terminal fragments of mutant huntingtin develop neurologic abnormalities with predominant cytoplasmic inclusion pathology composed largely of a smaller proteolytic derivative. Tebbenkamp AT; Green C; Xu G; Denovan-Wright EM; Rising AC; Fromholt SE; Brown HH; Swing D; Mandel RJ; Tessarollo L; Borchelt DR Hum Mol Genet; 2011 Jul; 20(14):2770-82. PubMed ID: 21515588 [TBL] [Abstract][Full Text] [Related]
14. Ectopic expression of the striatal-enriched GTPase Rhes elicits cerebellar degeneration and an ataxia phenotype in Huntington's disease. Swarnkar S; Chen Y; Pryor WM; Shahani N; Page DT; Subramaniam S Neurobiol Dis; 2015 Oct; 82():66-77. PubMed ID: 26048156 [TBL] [Abstract][Full Text] [Related]
15. Green tea (-)-epigallocatechin-gallate modulates early events in huntingtin misfolding and reduces toxicity in Huntington's disease models. Ehrnhoefer DE; Duennwald M; Markovic P; Wacker JL; Engemann S; Roark M; Legleiter J; Marsh JL; Thompson LM; Lindquist S; Muchowski PJ; Wanker EE Hum Mol Genet; 2006 Sep; 15(18):2743-51. PubMed ID: 16893904 [TBL] [Abstract][Full Text] [Related]
17. Neuroprotective effects of PPAR-γ agonist rosiglitazone in N171-82Q mouse model of Huntington's disease. Jin J; Albertz J; Guo Z; Peng Q; Rudow G; Troncoso JC; Ross CA; Duan W J Neurochem; 2013 May; 125(3):410-9. PubMed ID: 23373812 [TBL] [Abstract][Full Text] [Related]
18. Partial depletion of CREB-binding protein reduces life expectancy in a mouse model of Huntington disease. Klevytska AM; Tebbenkamp AT; Savonenko AV; Borchelt DR J Neuropathol Exp Neurol; 2010 Apr; 69(4):396-404. PubMed ID: 20448484 [TBL] [Abstract][Full Text] [Related]