BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

183 related articles for article (PubMed ID: 18403059)

  • 1. 2-[2-Substituted-3-(3,4-dichlorobenzylamino)propylamino]-1H-quinolin-4-ones as Staphylococcus aureus methionyl-tRNA synthetase inhibitors.
    Farhanullah ; Kang T; Yoon EJ; Choi EC; Kim S; Lee J
    Eur J Med Chem; 2009 Jan; 44(1):239-50. PubMed ID: 18403059
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Design and synthesis of quinolinones as methionyl-tRNA synthetase inhibitors.
    Farhanullah ; Kim SY; Yoon EJ; Choi EC; Kim S; Kang T; Samrin F; Puri S; Lee J
    Bioorg Med Chem; 2006 Nov; 14(21):7154-9. PubMed ID: 16854585
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Definition of the heterocyclic pharmacophore of bacterial methionyl tRNA synthetase inhibitors: potent antibacterially active non-quinolone analogues.
    Jarvest RL; Armstrong SA; Berge JM; Brown P; Elder JS; Brown MJ; Copley RC; Forrest AK; Hamprecht DW; O'Hanlon PJ; Mitchell DJ; Rittenhouse S; Witty DR
    Bioorg Med Chem Lett; 2004 Aug; 14(15):3937-41. PubMed ID: 15225702
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Nanomolar inhibitors of Staphylococcus aureus methionyl tRNA synthetase with potent antibacterial activity against gram-positive pathogens.
    Jarvest RL; Berge JM; Berry V; Boyd HF; Brown MJ; Elder JS; Forrest AK; Fosberry AP; Gentry DR; Hibbs MJ; Jaworski DD; O'Hanlon PJ; Pope AJ; Rittenhouse S; Sheppard RJ; Slater-Radosti C; Worby A
    J Med Chem; 2002 May; 45(10):1959-62. PubMed ID: 11985462
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Potent and selective inhibitors of bacterial methionyl tRNA synthetase derived from an oxazolone-dipeptide scaffold.
    Tandon M; Coffen DL; Gallant P; Keith D; Ashwell MA
    Bioorg Med Chem Lett; 2004 Apr; 14(8):1909-11. PubMed ID: 15050625
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis and antibacterial activity of N-(5-benzylthio-1,3,4-thiadiazol-2-yl) and N-(5-benzylsulfonyl-1,3,4-thiadiazol-2-yl)piperazinyl quinolone derivatives.
    Foroumadi A; Emami S; Hassanzadeh A; Rajaee M; Sokhanvar K; Moshafi MH; Shafiee A
    Bioorg Med Chem Lett; 2005 Oct; 15(20):4488-92. PubMed ID: 16105736
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Conformational restriction of methionyl tRNA synthetase inhibitors leading to analogues with potent inhibition and excellent gram-positive antibacterial activity.
    Jarvest RL; Berge JM; Brown P; Houge-Frydrych CS; O'Hanlon PJ; McNair DJ; Pope AJ; Rittenhouse S
    Bioorg Med Chem Lett; 2003 Apr; 13(7):1265-8. PubMed ID: 12657260
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A new class of anti-MRSA and anti-VRE agents: preparation and antibacterial activities of indole-containing compounds.
    Yamamoto Y; Kurazono M
    Bioorg Med Chem Lett; 2007 Mar; 17(6):1626-8. PubMed ID: 17254785
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis and structure-activity relationship of 7-(substituted)-aminomethyl-4-quinolone-3-carboxylic acid derivatives.
    Zhang Z; Yu A; Zhou W
    Bioorg Med Chem; 2007 Dec; 15(23):7274-80. PubMed ID: 17826097
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Preparation, antibacterial evaluation and preliminary structure-activity relationship (SAR) study of benzothiazol- and benzoxazol-2-amine derivatives.
    Ouyang L; Huang Y; Zhao Y; He G; Xie Y; Liu J; He J; Liu B; Wei Y
    Bioorg Med Chem Lett; 2012 May; 22(9):3044-9. PubMed ID: 22494615
    [TBL] [Abstract][Full Text] [Related]  

  • 11. [Synthesis and antibacterial activity of 7-(3-amino-4-alkoxyimino-1 -piperidyl) -quinolones].
    Wang XY; Guo Q; Wang YC; Liu BQ; Liu ML; Sun LY; Guo HY
    Yao Xue Xue Bao; 2008 Aug; 43(8):819-27. PubMed ID: 18956774
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis and antibacterial activity of N-[2-[5-(methylthio)thiophen-2-yl]-2-oxoethyl] and N-[2-[5-(methylthio)thiophen-2-yl]-2-(oxyimino)ethyl]piperazinylquinolone derivatives.
    Foroumadi A; Oboudiat M; Emami S; Karimollah A; Saghaee L; Moshafi MH; Shafiee A
    Bioorg Med Chem; 2006 May; 14(10):3421-7. PubMed ID: 16427290
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Antibacterial 5'-O-(N-dipeptidyl)-sulfamoyladenosines.
    Van de Vijver P; Vondenhoff GH; Denivelle S; Rozenski J; Verhaegen J; Van Aerschot A; Herdewijn P
    Bioorg Med Chem; 2009 Jan; 17(1):260-9. PubMed ID: 19070499
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis and antibacterial activity of the 4-quinolone-3-carboxylic acid derivatives having a trifluoromethyl group as a novel N-1 substituent.
    Asahina Y; Araya I; Iwase K; Iinuma F; Hosaka M; Ishizaki T
    J Med Chem; 2005 May; 48(9):3443-6. PubMed ID: 15857152
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Development of Methionyl-tRNA Synthetase Inhibitors as Antibiotics for Gram-Positive Bacterial Infections.
    Faghih O; Zhang Z; Ranade RM; Gillespie JR; Creason SA; Huang W; Shibata S; Barros-Álvarez X; Verlinde CLMJ; Hol WGJ; Fan E; Buckner FS
    Antimicrob Agents Chemother; 2017 Nov; 61(11):. PubMed ID: 28848016
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Rapid identification of antibacterial agents effective against Staphylococcus aureus using small-molecule macroarrays.
    Bowman MD; O'Neill JC; Stringer JR; Blackwell HE
    Chem Biol; 2007 Apr; 14(4):351-7. PubMed ID: 17462570
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis and evaluation of amphiphilic cationic quinine-derived for antibacterial activity against methicillin-resistant Staphylococcus aureus.
    Lv J; Qian Y; Liu T; Wang Y
    Bioorg Med Chem Lett; 2007 Aug; 17(15):4102-6. PubMed ID: 17570664
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis and antibacterial studies of binaphthyl-based tripeptoids. Part 2.
    Bremner JB; Keller PA; Pyne SG; Boyle TP; Brkic Z; Morgan J; Somphol K; Coates JA; Deadman J; Rhodes DI
    Bioorg Med Chem; 2010 Jul; 18(13):4793-800. PubMed ID: 20627739
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Pharmacophore identification and virtual screening for methionyl-tRNA synthetase inhibitors.
    Bharatham N; Bharatham K; Lee KW
    J Mol Graph Model; 2007 Mar; 25(6):813-23. PubMed ID: 16996282
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Identification of novel inhibitors of methionyl-tRNA synthetase (MetRS) by virtual screening.
    Finn J; Stidham M; Hilgers M; G C K
    Bioorg Med Chem Lett; 2008 Jul; 18(14):3932-7. PubMed ID: 18590962
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.