338 related articles for article (PubMed ID: 18403596)
1. Cross-species comparison of human and mouse intestinal polyps reveals conserved mechanisms in adenomatous polyposis coli (APC)-driven tumorigenesis.
Gaspar C; Cardoso J; Franken P; Molenaar L; Morreau H; Möslein G; Sampson J; Boer JM; de Menezes RX; Fodde R
Am J Pathol; 2008 May; 172(5):1363-80. PubMed ID: 18403596
[TBL] [Abstract][Full Text] [Related]
2. A targeted constitutive mutation in the APC tumor suppressor gene underlies mammary but not intestinal tumorigenesis.
Gaspar C; Franken P; Molenaar L; Breukel C; van der Valk M; Smits R; Fodde R
PLoS Genet; 2009 Jul; 5(7):e1000547. PubMed ID: 19578404
[TBL] [Abstract][Full Text] [Related]
3. The armadillo repeat domain of Apc suppresses intestinal tumorigenesis.
Crist RC; Roth JJ; Baran AA; McEntee BJ; Siracusa LD; Buchberg AM
Mamm Genome; 2010 Oct; 21(9-10):450-7. PubMed ID: 20886217
[TBL] [Abstract][Full Text] [Related]
4. Haploinsufficiency of Krüppel-like factor 4 promotes adenomatous polyposis coli dependent intestinal tumorigenesis.
Ghaleb AM; McConnell BB; Nandan MO; Katz JP; Kaestner KH; Yang VW
Cancer Res; 2007 Aug; 67(15):7147-54. PubMed ID: 17671182
[TBL] [Abstract][Full Text] [Related]
5. Activator protein 2alpha suppresses intestinal tumorigenesis in the Apc(min) mouse.
Li Q; Löhr CV; Dashwood RH
Cancer Lett; 2009 Sep; 283(1):36-42. PubMed ID: 19376641
[TBL] [Abstract][Full Text] [Related]
6. The 'just-right' signaling model: APC somatic mutations are selected based on a specific level of activation of the beta-catenin signaling cascade.
Albuquerque C; Breukel C; van der Luijt R; Fidalgo P; Lage P; Slors FJ; Leitão CN; Fodde R; Smits R
Hum Mol Genet; 2002 Jun; 11(13):1549-60. PubMed ID: 12045208
[TBL] [Abstract][Full Text] [Related]
7. The effect of a germline mutation in the APC gene on β-catenin in human embryonic stem cells.
Yedid N; Kalma Y; Malcov M; Amit A; Kariv R; Caspi M; Rosin-Arbesfeld R; Ben-Yosef D
BMC Cancer; 2016 Dec; 16(1):952. PubMed ID: 28010732
[TBL] [Abstract][Full Text] [Related]
8. The threshold level of adenomatous polyposis coli protein for mouse intestinal tumorigenesis.
Li Q; Ishikawa TO; Oshima M; Taketo MM
Cancer Res; 2005 Oct; 65(19):8622-7. PubMed ID: 16204028
[TBL] [Abstract][Full Text] [Related]
9. A knock-in mouse model reveals roles for nuclear Apc in cell proliferation, Wnt signal inhibition and tumor suppression.
Zeineldin M; Cunningham J; McGuinness W; Alltizer P; Cowley B; Blanchat B; Xu W; Pinson D; Neufeld KL
Oncogene; 2012 May; 31(19):2423-37. PubMed ID: 21996741
[TBL] [Abstract][Full Text] [Related]
10. Ovarian steroid cell tumor with biallelic adenomatous polyposis coli inactivation in a patient with familial adenomatous polyposis.
Hu PJ; Knoepp SM; Wu R; Cho KR
Genes Chromosomes Cancer; 2012 Mar; 51(3):283-9. PubMed ID: 22120905
[TBL] [Abstract][Full Text] [Related]
11. Novel read through agent: ZKN-0013 demonstrates efficacy in APC
Graf MR; Apte S; Terzo E; Padhye S; Shi S; Cox MK; Clark RB; Modur V; Badarinarayana V
J Mol Med (Berl); 2023 Apr; 101(4):375-385. PubMed ID: 36808265
[TBL] [Abstract][Full Text] [Related]
12. Mutation cluster region, association between germline and somatic mutations and genotype-phenotype correlation in upper gastrointestinal familial adenomatous polyposis.
Groves C; Lamlum H; Crabtree M; Williamson J; Taylor C; Bass S; Cuthbert-Heavens D; Hodgson S; Phillips R; Tomlinson I
Am J Pathol; 2002 Jun; 160(6):2055-61. PubMed ID: 12057910
[TBL] [Abstract][Full Text] [Related]
13. MicroRNA-494 promotes cancer progression and targets adenomatous polyposis coli in colorectal cancer.
Zhang Y; Guo L; Li Y; Feng GH; Teng F; Li W; Zhou Q
Mol Cancer; 2018 Jan; 17(1):1. PubMed ID: 29304823
[TBL] [Abstract][Full Text] [Related]
14. miR-155 Is Downregulated in Familial Adenomatous Polyposis and Modulates WNT Signaling by Targeting AXIN1 and TCF4.
Prossomariti A; Piazzi G; D'Angelo L; Miccoli S; Turchetti D; Alquati C; Montagna C; Bazzoli F; Ricciardiello L
Mol Cancer Res; 2018 Dec; 16(12):1965-1976. PubMed ID: 30072583
[TBL] [Abstract][Full Text] [Related]
15. Role of oncogenic K-Ras in cancer stem cell activation by aberrant Wnt/β-catenin signaling.
Moon BS; Jeong WJ; Park J; Kim TI; Min do S; Choi KY
J Natl Cancer Inst; 2014 Feb; 106(2):djt373. PubMed ID: 24491301
[TBL] [Abstract][Full Text] [Related]
16. [Familial adenomatous polyposis syndrome (FAP): pathogenesis and molecular mechanisms].
Friedrich A; Kullmann F
Med Klin (Munich); 2003 Dec; 98(12):776-82. PubMed ID: 14685680
[TBL] [Abstract][Full Text] [Related]
17. Understanding phenotypic variation in rodent models with germline Apc mutations.
Zeineldin M; Neufeld KL
Cancer Res; 2013 Apr; 73(8):2389-99. PubMed ID: 23580574
[TBL] [Abstract][Full Text] [Related]
18. Role of adenomatous polyposis coli (APC) gene mutations in the pathogenesis of colorectal cancer; current status and perspectives.
Aghabozorgi AS; Bahreyni A; Soleimani A; Bahrami A; Khazaei M; Ferns GA; Avan A; Hassanian SM
Biochimie; 2019 Feb; 157():64-71. PubMed ID: 30414835
[TBL] [Abstract][Full Text] [Related]
19. Rapamycin inhibition of polyposis and progression to dysplasia in a mouse model.
Hardiman KM; Liu J; Feng Y; Greenson JK; Fearon ER
PLoS One; 2014; 9(4):e96023. PubMed ID: 24763434
[TBL] [Abstract][Full Text] [Related]
20. Nrf2 knockout enhances intestinal tumorigenesis in Apc(min/+) mice due to attenuation of anti-oxidative stress pathway while potentiates inflammation.
Cheung KL; Lee JH; Khor TO; Wu TY; Li GX; Chan J; Yang CS; Kong AN
Mol Carcinog; 2014 Jan; 53(1):77-84. PubMed ID: 22911891
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]