190 related articles for article (PubMed ID: 18404765)
21. Highly selective aza-nitrile inhibitors for cathepsin K, structural optimization and molecular modeling.
Yuan XY; Fu DY; Ren XF; Fang X; Wang L; Zou S; Wu Y
Org Biomol Chem; 2013 Sep; 11(35):5847-52. PubMed ID: 23900712
[TBL] [Abstract][Full Text] [Related]
22. Dipeptidyl nitriles as human dipeptidyl peptidase I inhibitors.
Bondebjerg J; Fuglsang H; Valeur KR; Pedersen J; Naerum L
Bioorg Med Chem Lett; 2006 Jul; 16(13):3614-7. PubMed ID: 16647256
[TBL] [Abstract][Full Text] [Related]
23. Inactivation of cysteine proteases.
Govardhan CP; Abeles RH
Arch Biochem Biophys; 1996 Jun; 330(1):110-4. PubMed ID: 8651683
[TBL] [Abstract][Full Text] [Related]
24. Aza-peptide epoxides: potent and selective inhibitors of Schistosoma mansoni and pig kidney legumains (asparaginyl endopeptidases).
James KE; Götz MG; Caffrey CR; Hansell E; Carter W; Barrett AJ; McKerrow JH; Powers JC
Biol Chem; 2003 Dec; 384(12):1613-8. PubMed ID: 14719804
[TBL] [Abstract][Full Text] [Related]
25. Peptidyl allyl sulfones: a new class of inhibitors for clan CA cysteine proteases.
Götz MG; Caffrey CR; Hansell E; McKerrow JH; Powers JC
Bioorg Med Chem; 2004 Oct; 12(19):5203-11. PubMed ID: 15351403
[TBL] [Abstract][Full Text] [Related]
26. Mechanistic studies on the inactivation of papain by epoxysuccinyl inhibitors.
Meara JP; Rich DH
J Med Chem; 1996 Aug; 39(17):3357-66. PubMed ID: 8765519
[TBL] [Abstract][Full Text] [Related]
27. Active Site Mapping of Human Cathepsin F with Dipeptide Nitrile Inhibitors.
Schmitz J; Furtmann N; Ponert M; Frizler M; Löser R; Bartz U; Bajorath J; Gütschow M
ChemMedChem; 2015 Aug; 10(8):1365-77. PubMed ID: 26119278
[TBL] [Abstract][Full Text] [Related]
28. Design, synthesis, and evaluation of in vivo potency and selectivity of epoxysuccinyl-based inhibitors of papain-family cysteine proteases.
Sadaghiani AM; Verhelst SH; Gocheva V; Hill K; Majerova E; Stinson S; Joyce JA; Bogyo M
Chem Biol; 2007 May; 14(5):499-511. PubMed ID: 17524981
[TBL] [Abstract][Full Text] [Related]
29. Facing the gem-dialkyl effect in enzyme inhibitor design: preparation of homocycloleucine-based azadipeptide nitriles.
Frizler M; Lohr F; Lülsdorff M; Gütschow M
Chemistry; 2011 Oct; 17(41):11419-23. PubMed ID: 21898616
[No Abstract] [Full Text] [Related]
30. New cathepsin inhibitors to explore the fluorophilic properties of the S2 pocket of cathepsin B: design, synthesis, and biological evaluation.
Fustero S; Rodrigo V; Sánchez-Roselló M; del Pozo C; Timoneda J; Frizler M; Sisay MT; Bajorath J; Calle LP; Cañada FJ; Jiménez-Barbero J; Gütschow M
Chemistry; 2011 May; 17(19):5256-60. PubMed ID: 21452179
[No Abstract] [Full Text] [Related]
31. Novel purine nitrile derived inhibitors of the cysteine protease cathepsin K.
Altmann E; Cowan-Jacob SW; Missbach M
J Med Chem; 2004 Nov; 47(24):5833-6. PubMed ID: 15537340
[TBL] [Abstract][Full Text] [Related]
32. A generally applicable method for assessing the electrophilicity and reactivity of diverse nitrile-containing compounds.
Oballa RM; Truchon JF; Bayly CI; Chauret N; Day S; Crane S; Berthelette C
Bioorg Med Chem Lett; 2007 Feb; 17(4):998-1002. PubMed ID: 17157022
[TBL] [Abstract][Full Text] [Related]
33. "Click" synthesis of small molecule-peptide conjugates for organelle-specific delivery and inhibition of lysosomal cysteine proteases.
Loh Y; Shi H; Hu M; Yao SQ
Chem Commun (Camb); 2010 Nov; 46(44):8407-9. PubMed ID: 20931108
[TBL] [Abstract][Full Text] [Related]
34. Dipeptide nitrile inhibitors of cathepsin K.
Altmann E; Aichholz R; Betschart C; Buhl T; Green J; Lattmann R; Missbach M
Bioorg Med Chem Lett; 2006 May; 16(9):2549-54. PubMed ID: 16480867
[TBL] [Abstract][Full Text] [Related]
35. Synthesis and evaluation of chloromethyl sulfoxides as a new class of selective irreversible cysteine protease inhibitors.
Brouwer AJ; Bunschoten A; Liskamp RM
Bioorg Med Chem; 2007 Nov; 15(22):6985-93. PubMed ID: 17869119
[TBL] [Abstract][Full Text] [Related]
36. A comparative study of warheads for design of cysteine protease inhibitors.
Silva DG; Ribeiro JFR; De Vita D; Cianni L; Franco CH; Freitas-Junior LH; Moraes CB; Rocha JR; Burtoloso ACB; Kenny PW; Leitão A; Montanari CA
Bioorg Med Chem Lett; 2017 Nov; 27(22):5031-5035. PubMed ID: 29054358
[TBL] [Abstract][Full Text] [Related]
37. Design, synthesis, and evaluation of aza-peptide epoxides as selective and potent inhibitors of caspases-1, -3, -6, and -8.
James KE; Asgian JL; Li ZZ; Ekici OD; Rubin JR; Mikolajczyk J; Salvesen GS; Powers JC
J Med Chem; 2004 Mar; 47(6):1553-74. PubMed ID: 14998341
[TBL] [Abstract][Full Text] [Related]
38. eta(1)-N-succinimidato complexes of iron, molybdenum and tungsten as reversible inhibitors of papain.
Rudolf B; Salmain M; Martel A; Palusiak M; Zakrzewski J
J Inorg Biochem; 2009 Aug; 103(8):1162-8. PubMed ID: 19616302
[TBL] [Abstract][Full Text] [Related]
39. New m-calpain substrate-based azapeptide inhibitors.
Bánóczi Z; Tantos Á; Farkas A; Majer Z; Dókus LE; Tompa P; Hudecz F
J Pept Sci; 2013 Jun; 19(6):370-6. PubMed ID: 23613308
[TBL] [Abstract][Full Text] [Related]
40. Seco-prolinenitrile inhibitors of dipeptidyl peptidase IV define minimal pharmacophore requirements at P1.
Magnin DR; Taunk PC; Robertson JG; Wang A; Marcinkeviciene J; Kirby MS; Hamann LG
Bioorg Med Chem Lett; 2006 Mar; 16(6):1731-4. PubMed ID: 16376077
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]