BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

144 related articles for article (PubMed ID: 18404777)

  • 1. Synthesis, cytotoxicity and protein kinase C inhibition of arylpyrrolylmaleimides.
    Xu GQ; Zhang C; Zhang L; Zhou XL; Yang B; He QJ; Hu YZ
    Arch Pharm (Weinheim); 2008 May; 341(5):273-80. PubMed ID: 18404777
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis and evaluation of novel 7-azaindazolyl-indolyl-maleimide derivatives as antitumor agents and protein kinase C inhibitors.
    Ye Q; Cao J; Zhou X; Lv D; He Q; Yang B; Hu Y
    Bioorg Med Chem; 2009 Jul; 17(13):4763-72. PubMed ID: 19447039
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis and cytotoxicity of novel 3-amino-4-indolylmaleimide derivatives.
    Zhao SY; Yang YW; Zhang HQ; Yue Y; Fan M
    Arch Pharm Res; 2011 Apr; 34(4):519-26. PubMed ID: 21544716
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis and PKCtheta inhibitory activity of a series of 4-(indol-5-ylamino)thieno[2,3-b]pyridine-5-carbonitriles.
    Boschelli DH; Wu B; Barrios Sosa AC; Chen J; Asselin M; Cole DC; Lee J; Yang X; Chaudhary D
    Bioorg Med Chem Lett; 2008 May; 18(9):2850-3. PubMed ID: 18434148
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Design and synthesis of new potent anticancer pyrazoles with high FLT3 kinase inhibitory selectivity.
    El-Deeb IM; Lee SH
    Bioorg Med Chem; 2010 Jun; 18(11):3961-73. PubMed ID: 20472440
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis and activity of quinolinyl-methylene-thiazolinones as potent and selective cyclin-dependent kinase 1 inhibitors.
    Chen S; Chen L; Le NT; Zhao C; Sidduri A; Lou JP; Michoud C; Portland L; Jackson N; Liu JJ; Konzelmann F; Chi F; Tovar C; Xiang Q; Chen Y; Wen Y; Vassilev LT
    Bioorg Med Chem Lett; 2007 Apr; 17(8):2134-8. PubMed ID: 17303421
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis of 1,7-annulated indoles and their applications in the studies of cyclin dependent kinase inhibitors.
    Zhu G; Conner SE; Zhou X; Chan HK; Shih C; Engler TA; Al-Awar RS; Brooks HB; Watkins SA; Spencer CD; Schultz RM; Dempsey JA; Considine EL; Patel BR; Ogg CA; Vasudevan V; Lytle ML
    Bioorg Med Chem Lett; 2004 Jun; 14(12):3057-61. PubMed ID: 15149644
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Design, synthesis and structure-activity relationships of novel biarylamine-based Met kinase inhibitors.
    Williams DK; Chen XT; Tarby C; Kaltenbach R; Cai ZW; Tokarski JS; An Y; Sack JS; Wautlet B; Gullo-Brown J; Henley BJ; Jeyaseelan R; Kellar K; Manne V; Trainor GL; Lombardo LJ; Fargnoli J; Borzilleri RM
    Bioorg Med Chem Lett; 2010 May; 20(9):2998-3002. PubMed ID: 20382527
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis of 3-substituted-2-oxoindole analogues and their evaluation as kinase inhibitors, anticancer and antiangiogenic agents.
    Abadi AH; Abou-Seri SM; Abdel-Rahman DE; Klein C; Lozach O; Meijer L
    Eur J Med Chem; 2006 Mar; 41(3):296-305. PubMed ID: 16494969
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A one-pot synthesis and biological activity of ageladine A and analogues.
    Shengule SR; Loa-Kum-Cheung WL; Parish CR; Blairvacq M; Meijer L; Nakao Y; Karuso P
    J Med Chem; 2011 Apr; 54(7):2492-503. PubMed ID: 21413800
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Design and synthesis of new anticancer pyrimidines with multiple-kinase inhibitory effect.
    El-Deeb IM; Lee SH
    Bioorg Med Chem; 2010 Jun; 18(11):3860-74. PubMed ID: 20471842
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structure-based design and synthesis of novel macrocyclic pyrazolo[1,5-a] [1,3,5]triazine compounds as potent inhibitors of protein kinase CK2 and their anticancer activities.
    Nie Z; Perretta C; Erickson P; Margosiak S; Lu J; Averill A; Almassy R; Chu S
    Bioorg Med Chem Lett; 2008 Jan; 18(2):619-23. PubMed ID: 18055206
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis and biological evaluation of new 1,5-diazaanthraquinones with cytotoxic activity.
    Manzanaro S; Vicent MJ; Martín MJ; Salvador-Tormo N; Pérez JM; del Mar Blanco M; Avendaño C; Menéndez JC; de la Fuente JA
    Bioorg Med Chem; 2004 Dec; 12(24):6505-15. PubMed ID: 15556767
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The discovery of highly selective erbB2 (Her2) inhibitors for the treatment of cancer.
    Lippa B; Kauffman GS; Arcari J; Kwan T; Chen J; Hungerford W; Bhattacharya S; Zhao X; Williams C; Xiao J; Pustilnik L; Su C; Moyer JD; Ma L; Campbell M; Steyn S
    Bioorg Med Chem Lett; 2007 Jun; 17(11):3081-6. PubMed ID: 17398092
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Inhibition of Src kinase activity by 7-[(2,4-dichloro-5-methoxyphenyl)amino]-2-heteroaryl-thieno[3,2-b]pyridine-6-carbonitriles.
    Boschelli DH; Wu B; Barrios Sosa AC; Chen JJ; Golas JM; Boschelli F
    Bioorg Med Chem Lett; 2005 Nov; 15(21):4681-4. PubMed ID: 16125383
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis and cytotoxic activities of 4,5-diarylisoxazoles.
    Sun CM; Lin LG; Yu HJ; Cheng CY; Tsai YC; Chu CW; Din YH; Chau YP; Don MJ
    Bioorg Med Chem Lett; 2007 Feb; 17(4):1078-81. PubMed ID: 17127061
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis and evaluation of 2,7-diamino-thiazolo[4,5-d] pyrimidine analogues as anti-tumor epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors.
    Lin R; Johnson SG; Connolly PJ; Wetter SK; Binnun E; Hughes TV; Murray WV; Pandey NB; Moreno-Mazza SJ; Adams M; Fuentes-Pesquera AR; Middleton SA
    Bioorg Med Chem Lett; 2009 Apr; 19(8):2333-7. PubMed ID: 19286381
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis and biological evaluation of 2,3-diarylimidazo[1,2-a]pyridines as antileishmanial agents.
    Marhadour S; Marchand P; Pagniez F; Bazin MA; Picot C; Lozach O; Ruchaud S; Antoine M; Meijer L; Rachidi N; Le Pape P
    Eur J Med Chem; 2012 Dec; 58():543-56. PubMed ID: 23164660
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis and evaluation of pyrazolo[3,4-b]pyridine CDK1 inhibitors as anti-tumor agents.
    Lin R; Connolly PJ; Lu Y; Chiu G; Li S; Yu Y; Huang S; Li X; Emanuel SL; Middleton SA; Gruninger RH; Adams M; Fuentes-Pesquera AR; Greenberger LM
    Bioorg Med Chem Lett; 2007 Aug; 17(15):4297-302. PubMed ID: 17532631
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis and biological evaluation of some novel polysubstituted pyrimidine derivatives as potential antimicrobial and anticancer agents.
    Rostom SA; Ashour HM; Abd El Razik HA
    Arch Pharm (Weinheim); 2009 May; 342(5):299-310. PubMed ID: 19415663
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.