These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

121 related articles for article (PubMed ID: 18405662)

  • 21. Ferritin light chain interacts with PEN-2 and affects γ-secretase activity.
    Li X; Liu Y; Zheng Q; Yao G; Cheng P; Bu G; Xu H; Zhang YW
    Neurosci Lett; 2013 Aug; 548():90-4. PubMed ID: 23685131
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Purification and characterization of the human gamma-secretase complex.
    Fraering PC; Ye W; Strub JM; Dolios G; LaVoie MJ; Ostaszewski BL; van Dorsselaer A; Wang R; Selkoe DJ; Wolfe MS
    Biochemistry; 2004 Aug; 43(30):9774-89. PubMed ID: 15274632
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Caspase cleaved presenilin-1 is part of active gamma-secretase complexes.
    Hansson CA; Popescu BO; Laudon H; Cedazo-Minguez A; Popescu LM; Winblad B; Ankarcrona M
    J Neurochem; 2006 Apr; 97(2):356-64. PubMed ID: 16539675
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Inhibitors of γ-secretase stabilize the complex and differentially affect processing of amyloid precursor protein and other substrates.
    Barthet G; Shioi J; Shao Z; Ren Y; Georgakopoulos A; Robakis NK
    FASEB J; 2011 Sep; 25(9):2937-46. PubMed ID: 21597003
    [TBL] [Abstract][Full Text] [Related]  

  • 25. gamma-Secretase complexes containing N- and C-terminal fragments of different presenilin origin retain normal gamma-secretase activity.
    Strömberg K; Hansson EM; Laudon H; Bergstedt S; Näslund J; Lundkvist J; Lendahl U
    J Neurochem; 2005 Nov; 95(3):880-90. PubMed ID: 16135086
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Immature nicastrin stabilizes APH-1 independent of PEN-2 and presenilin: identification of nicastrin mutants that selectively interact with APH-1.
    Shirotani K; Edbauer D; Kostka M; Steiner H; Haass C
    J Neurochem; 2004 Jun; 89(6):1520-7. PubMed ID: 15189355
    [TBL] [Abstract][Full Text] [Related]  

  • 27. p53-dependent control of cell death by nicastrin: lack of requirement for presenilin-dependent gamma-secretase complex.
    Pardossi-Piquard R; Dunys J; Giaime E; Guillot-Sestier MV; St George-Hyslop P; Checler F; Alves da Costa C
    J Neurochem; 2009 Apr; 109(1):225-37. PubMed ID: 19187441
    [TBL] [Abstract][Full Text] [Related]  

  • 28. The role of TMP21 in trafficking and amyloid-β precursor protein (APP) processing in Alzheimer's disease.
    Bromley-Brits K; Song W
    Curr Alzheimer Res; 2012 May; 9(4):411-24. PubMed ID: 22299712
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Pharmacological evidences for DFK167-sensitive presenilin-independent gamma-secretase-like activity.
    Sevalle J; Ayral E; Hernandez JF; Martinez J; Checler F
    J Neurochem; 2009 Jul; 110(1):275-83. PubMed ID: 19457123
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Activation and intrinsic gamma-secretase activity of presenilin 1.
    Ahn K; Shelton CC; Tian Y; Zhang X; Gilchrist ML; Sisodia SS; Li YM
    Proc Natl Acad Sci U S A; 2010 Dec; 107(50):21435-40. PubMed ID: 21115843
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Green Tea Seed Isolated Theasaponin E1 Ameliorates AD Promoting Neurotoxic Pathogenesis by Attenuating Aβ Peptide Levels in SweAPP N2a Cells.
    Khan MI; Shin JH; Kim MY; Shin TS; Kim JD
    Molecules; 2020 May; 25(10):. PubMed ID: 32429462
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Carboxyl-terminal fragments of Alzheimer beta-amyloid precursor protein accumulate in restricted and unpredicted intracellular compartments in presenilin 1-deficient cells.
    Chen F; Yang DS; Petanceska S; Yang A; Tandon A; Yu G; Rozmahel R; Ghiso J; Nishimura M; Zhang DM; Kawarai T; Levesque G; Mills J; Levesque L; Song YQ; Rogaeva E; Westaway D; Mount H; Gandy S; St George-Hyslop P; Fraser PE
    J Biol Chem; 2000 Nov; 275(47):36794-802. PubMed ID: 10962005
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Dissociated phenotypes in presenilin transgenic mice define functionally distinct gamma-secretases.
    Mastrangelo P; Mathews PM; Chishti MA; Schmidt SD; Gu Y; Yang J; Mazzella MJ; Coomaraswamy J; Horne P; Strome B; Pelly H; Levesque G; Ebeling C; Jiang Y; Nixon RA; Rozmahel R; Fraser PE; St George-Hyslop P; Carlson GA; Westaway D
    Proc Natl Acad Sci U S A; 2005 Jun; 102(25):8972-7. PubMed ID: 15951428
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Auraptene increases the production of amyloid-β via c-Jun N-terminal kinase-dependent activation of γ-secretase.
    Jung CG; Uhm KO; Horike H; Kim MJ; Misumi S; Ishida A; Ueda Y; Choi EK; Kim YS; Michikawa M; Hida H
    J Alzheimers Dis; 2015; 43(4):1215-28. PubMed ID: 25147119
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Ubiquilin regulates presenilin endoproteolysis and modulates gamma-secretase components, Pen-2 and nicastrin.
    Massey LK; Mah AL; Monteiro MJ
    Biochem J; 2005 Nov; 391(Pt 3):513-25. PubMed ID: 15975090
    [TBL] [Abstract][Full Text] [Related]  

  • 36. γ-Secretase Modulators and APH1 Isoforms Modulate γ-Secretase Cleavage but Not Position of ε-Cleavage of the Amyloid Precursor Protein (APP).
    Lessard CB; Cottrell BA; Maruyama H; Suresh S; Golde TE; Koo EH
    PLoS One; 2015; 10(12):e0144758. PubMed ID: 26678856
    [TBL] [Abstract][Full Text] [Related]  

  • 37. p53, a pivotal effector of a functional cross-talk linking presenilins and Pen-2.
    Checler F; Dunys J
    Neurodegener Dis; 2012; 10(1-4):52-5. PubMed ID: 22205087
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Ubiquilin-1 modulates γ-secretase-mediated ε-site cleavage in neuronal cells.
    Viswanathan J; Haapasalo A; Kurkinen KM; Natunen T; Mäkinen P; Bertram L; Soininen H; Tanzi RE; Hiltunen M
    Biochemistry; 2013 Jun; 52(22):3899-912. PubMed ID: 23663107
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Mutant presenilins specifically elevate the levels of the 42 residue beta-amyloid peptide in vivo: evidence for augmentation of a 42-specific gamma secretase.
    Jankowsky JL; Fadale DJ; Anderson J; Xu GM; Gonzales V; Jenkins NA; Copeland NG; Lee MK; Younkin LH; Wagner SL; Younkin SG; Borchelt DR
    Hum Mol Genet; 2004 Jan; 13(2):159-70. PubMed ID: 14645205
    [TBL] [Abstract][Full Text] [Related]  

  • 40. PEN-2 enhances gamma-cleavage after presenilin heterodimer formation.
    Shiraishi H; Sai X; Wang HQ; Maeda Y; Kurono Y; Nishimura M; Yanagisawa K; Komano H
    J Neurochem; 2004 Sep; 90(6):1402-13. PubMed ID: 15341524
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 7.