357 related articles for article (PubMed ID: 18413257)
21. [Rheb-mTOR signaling pathway involved in tumor formation].
Sato T; Nakashima A; Tamanoi F
Tanpakushitsu Kakusan Koso; 2010 Jan; 55(1):11-7. PubMed ID: 20058701
[No Abstract] [Full Text] [Related]
22. RalA functions as an indispensable signal mediator for the nutrient-sensing system.
Maehama T; Tanaka M; Nishina H; Murakami M; Kanaho Y; Hanada K
J Biol Chem; 2008 Dec; 283(50):35053-9. PubMed ID: 18948269
[TBL] [Abstract][Full Text] [Related]
23. Intestinal cell kinase (ICK) promotes activation of mTOR complex 1 (mTORC1) through phosphorylation of Raptor Thr-908.
Wu D; Chapman JR; Wang L; Harris TE; Shabanowitz J; Hunt DF; Fu Z
J Biol Chem; 2012 Apr; 287(15):12510-9. PubMed ID: 22356909
[TBL] [Abstract][Full Text] [Related]
24. Insulin activation of Rheb, a mediator of mTOR/S6K/4E-BP signaling, is inhibited by TSC1 and 2.
Garami A; Zwartkruis FJ; Nobukuni T; Joaquin M; Roccio M; Stocker H; Kozma SC; Hafen E; Bos JL; Thomas G
Mol Cell; 2003 Jun; 11(6):1457-66. PubMed ID: 12820960
[TBL] [Abstract][Full Text] [Related]
25. Rheb and mTOR regulate neuronal polarity through Rap1B.
Li YH; Werner H; PĆ¼schel AW
J Biol Chem; 2008 Nov; 283(48):33784-92. PubMed ID: 18842593
[TBL] [Abstract][Full Text] [Related]
26. PRR5, a novel component of mTOR complex 2, regulates platelet-derived growth factor receptor beta expression and signaling.
Woo SY; Kim DH; Jun CB; Kim YM; Haar EV; Lee SI; Hegg JW; Bandhakavi S; Griffin TJ; Kim DH
J Biol Chem; 2007 Aug; 282(35):25604-12. PubMed ID: 17599906
[TBL] [Abstract][Full Text] [Related]
27. Rheb/mTOR activation and regulation in cancer: novel treatment strategies beyond rapamycin.
Babcock JT; Quilliam LA
Curr Drug Targets; 2011 Jul; 12(8):1223-31. PubMed ID: 21561413
[TBL] [Abstract][Full Text] [Related]
28. Raptor and Rheb negatively regulate skeletal myogenesis through suppression of insulin receptor substrate 1 (IRS1).
Ge Y; Yoon MS; Chen J
J Biol Chem; 2011 Oct; 286(41):35675-35682. PubMed ID: 21852229
[TBL] [Abstract][Full Text] [Related]
29. Redox regulates mammalian target of rapamycin complex 1 (mTORC1) activity by modulating the TSC1/TSC2-Rheb GTPase pathway.
Yoshida S; Hong S; Suzuki T; Nada S; Mannan AM; Wang J; Okada M; Guan KL; Inoki K
J Biol Chem; 2011 Sep; 286(37):32651-60. PubMed ID: 21784859
[TBL] [Abstract][Full Text] [Related]
30. Control of TSC2-Rheb signaling axis by arginine regulates mTORC1 activity.
Carroll B; Maetzel D; Maddocks OD; Otten G; Ratcliff M; Smith GR; Dunlop EA; Passos JF; Davies OR; Jaenisch R; Tee AR; Sarkar S; Korolchuk VI
Elife; 2016 Jan; 5():. PubMed ID: 26742086
[TBL] [Abstract][Full Text] [Related]
31. Amino acids activate mammalian target of rapamycin (mTOR) complex 1 without changing Rag GTPase guanyl nucleotide charging.
Oshiro N; Rapley J; Avruch J
J Biol Chem; 2014 Jan; 289(5):2658-74. PubMed ID: 24337580
[TBL] [Abstract][Full Text] [Related]
32. Identification of dominant negative mutants of Rheb GTPase and their use to implicate the involvement of human Rheb in the activation of p70S6K.
Tabancay AP; Gau CL; Machado IM; Uhlmann EJ; Gutmann DH; Guo L; Tamanoi F
J Biol Chem; 2003 Oct; 278(41):39921-30. PubMed ID: 12869548
[TBL] [Abstract][Full Text] [Related]
33. Hyperactivation of mammalian target of rapamycin (mTOR) signaling by a gain-of-function mutant of the Rheb GTPase.
Yan L; Findlay GM; Jones R; Procter J; Cao Y; Lamb RF
J Biol Chem; 2006 Jul; 281(29):19793-7. PubMed ID: 16728407
[TBL] [Abstract][Full Text] [Related]
34. Molecular mechanisms through which amino acids mediate signaling through the mammalian target of rapamycin.
Kimball SR; Jefferson LS
Curr Opin Clin Nutr Metab Care; 2004 Jan; 7(1):39-44. PubMed ID: 15090902
[TBL] [Abstract][Full Text] [Related]
35. Tumorigenic activity and therapeutic inhibition of Rheb GTPase.
Mavrakis KJ; Zhu H; Silva RL; Mills JR; Teruya-Feldstein J; Lowe SW; Tam W; Pelletier J; Wendel HG
Genes Dev; 2008 Aug; 22(16):2178-88. PubMed ID: 18708578
[TBL] [Abstract][Full Text] [Related]
36. PDK4 protein promotes tumorigenesis through activation of cAMP-response element-binding protein (CREB)-Ras homolog enriched in brain (RHEB)-mTORC1 signaling cascade.
Liu Z; Chen X; Wang Y; Peng H; Wang Y; Jing Y; Zhang H
J Biol Chem; 2014 Oct; 289(43):29739-49. PubMed ID: 25164809
[TBL] [Abstract][Full Text] [Related]
37. Lysosomal accumulation of mTOR is enhanced by rapamycin.
Ohsaki Y; Suzuki M; Shinohara Y; Fujimoto T
Histochem Cell Biol; 2010 Dec; 134(6):537-44. PubMed ID: 21063721
[TBL] [Abstract][Full Text] [Related]
38. Regulation of B-Raf kinase activity by tuberin and Rheb is mammalian target of rapamycin (mTOR)-independent.
Karbowniczek M; Cash T; Cheung M; Robertson GP; Astrinidis A; Henske EP
J Biol Chem; 2004 Jul; 279(29):29930-7. PubMed ID: 15150271
[TBL] [Abstract][Full Text] [Related]
39. Upregulation of the mammalian target of rapamycin complex 1 pathway by Ras homolog enriched in brain in pancreatic beta-cells leads to increased beta-cell mass and prevention of hyperglycemia.
Hamada S; Hara K; Hamada T; Yasuda H; Moriyama H; Nakayama R; Nagata M; Yokono K
Diabetes; 2009 Jun; 58(6):1321-32. PubMed ID: 19258434
[TBL] [Abstract][Full Text] [Related]
40. The Rheb switch 2 segment is critical for signaling to target of rapamycin complex 1.
Long X; Lin Y; Ortiz-Vega S; Busch S; Avruch J
J Biol Chem; 2007 Jun; 282(25):18542-18551. PubMed ID: 17470430
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]