BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

359 related articles for article (PubMed ID: 18414662)

  • 1. EWS/FLI mediates transcriptional repression via NKX2.2 during oncogenic transformation in Ewing's sarcoma.
    Owen LA; Kowalewski AA; Lessnick SL
    PLoS One; 2008 Apr; 3(4):e1965. PubMed ID: 18414662
    [TBL] [Abstract][Full Text] [Related]  

  • 2. EWS/FLI and its downstream target NR0B1 interact directly to modulate transcription and oncogenesis in Ewing's sarcoma.
    Kinsey M; Smith R; Iyer AK; McCabe ER; Lessnick SL
    Cancer Res; 2009 Dec; 69(23):9047-55. PubMed ID: 19920188
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Expression profiling of EWS/FLI identifies NKX2.2 as a critical target gene in Ewing's sarcoma.
    Smith R; Owen LA; Trem DJ; Wong JS; Whangbo JS; Golub TR; Lessnick SL
    Cancer Cell; 2006 May; 9(5):405-16. PubMed ID: 16697960
    [TBL] [Abstract][Full Text] [Related]  

  • 4. NR0B1 is required for the oncogenic phenotype mediated by EWS/FLI in Ewing's sarcoma.
    Kinsey M; Smith R; Lessnick SL
    Mol Cancer Res; 2006 Nov; 4(11):851-9. PubMed ID: 17114343
    [TBL] [Abstract][Full Text] [Related]  

  • 5. GSTM4 is a microsatellite-containing EWS/FLI target involved in Ewing's sarcoma oncogenesis and therapeutic resistance.
    Luo W; Gangwal K; Sankar S; Boucher KM; Thomas D; Lessnick SL
    Oncogene; 2009 Nov; 28(46):4126-32. PubMed ID: 19718047
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Caveolin-1 (CAV1) is a target of EWS/FLI-1 and a key determinant of the oncogenic phenotype and tumorigenicity of Ewing's sarcoma cells.
    Tirado OM; Mateo-Lozano S; Villar J; Dettin LE; Llort A; Gallego S; Ban J; Kovar H; Notario V
    Cancer Res; 2006 Oct; 66(20):9937-47. PubMed ID: 17047056
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Identification of target genes in their native cellular context: an analysis of EWS/FLI in Ewing's sarcoma.
    Owen LA; Lessnick SL
    Cell Cycle; 2006 Sep; 5(18):2049-53. PubMed ID: 16969112
    [TBL] [Abstract][Full Text] [Related]  

  • 8. BCL11B is up-regulated by EWS/FLI and contributes to the transformed phenotype in Ewing sarcoma.
    Wiles ET; Lui-Sargent B; Bell R; Lessnick SL
    PLoS One; 2013; 8(3):e59369. PubMed ID: 23527175
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A transcriptional profiling meta-analysis reveals a core EWS-FLI gene expression signature.
    Hancock JD; Lessnick SL
    Cell Cycle; 2008 Jan; 7(2):250-6. PubMed ID: 18256529
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Mechanism and relevance of EWS/FLI-mediated transcriptional repression in Ewing sarcoma.
    Sankar S; Bell R; Stephens B; Zhuo R; Sharma S; Bearss DJ; Lessnick SL
    Oncogene; 2013 Oct; 32(42):5089-100. PubMed ID: 23178492
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Transformation induced by Ewing's sarcoma associated EWS/FLI-1 is suppressed by KRAB/FLI-1.
    Chan D; Wilson TJ; Xu D; Cowdery HE; Sanij E; Hertzog PJ; Kola I
    Br J Cancer; 2003 Jan; 88(1):137-45. PubMed ID: 12556973
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Alteration of mesodermal cell differentiation by EWS/FLI-1, the oncogene implicated in Ewing's sarcoma.
    Eliazer S; Spencer J; Ye D; Olson E; Ilaria RL
    Mol Cell Biol; 2003 Jan; 23(2):482-92. PubMed ID: 12509448
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Small-molecule screen identifies modulators of EWS/FLI1 target gene expression and cell survival in Ewing's sarcoma.
    Boro A; PrĂȘtre K; Rechfeld F; Thalhammer V; Oesch S; Wachtel M; SchĂ€fer BW; Niggli FK
    Int J Cancer; 2012 Nov; 131(9):2153-64. PubMed ID: 22323082
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Ewing's sarcoma: general insights from a rare model.
    Davis S; Meltzer PS
    Cancer Cell; 2006 May; 9(5):331-2. PubMed ID: 16697953
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Microsatellites as EWS/FLI response elements in Ewing's sarcoma.
    Gangwal K; Sankar S; Hollenhorst PC; Kinsey M; Haroldsen SC; Shah AA; Boucher KM; Watkins WS; Jorde LB; Graves BJ; Lessnick SL
    Proc Natl Acad Sci U S A; 2008 Jul; 105(29):10149-54. PubMed ID: 18626011
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Junction region of EWS-FLI1 fusion protein has a dominant negative effect in Ewing's sarcoma in vitro.
    Jully B; Vijayalakshmi R; Gopal G; Sabitha K; Rajkumar T
    BMC Cancer; 2012 Nov; 12():513. PubMed ID: 23145994
    [TBL] [Abstract][Full Text] [Related]  

  • 17. EWS/FLI-1 silencing and gene profiling of Ewing cells reveal downstream oncogenic pathways and a crucial role for repression of insulin-like growth factor binding protein 3.
    Prieur A; Tirode F; Cohen P; Delattre O
    Mol Cell Biol; 2004 Aug; 24(16):7275-83. PubMed ID: 15282325
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Interference with the constitutive activation of ERK1 and ERK2 impairs EWS/FLI-1-dependent transformation.
    Silvany RE; Eliazer S; Wolff NC; Ilaria RL
    Oncogene; 2000 Sep; 19(39):4523-30. PubMed ID: 11002425
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Targeting of EWS/FLI-1 by RNA interference attenuates the tumor phenotype of Ewing's sarcoma cells in vitro.
    Chansky HA; Barahmand-Pour F; Mei Q; Kahn-Farooqi W; Zielinska-Kwiatkowska A; Blackburn M; Chansky K; Conrad EU; Bruckner JD; Greenlee TK; Yang L
    J Orthop Res; 2004 Jul; 22(4):910-7. PubMed ID: 15183454
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The Ewing's sarcoma oncoprotein EWS/FLI induces a p53-dependent growth arrest in primary human fibroblasts.
    Lessnick SL; Dacwag CS; Golub TR
    Cancer Cell; 2002 May; 1(4):393-401. PubMed ID: 12086853
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.