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2. EWS/FLI and its downstream target NR0B1 interact directly to modulate transcription and oncogenesis in Ewing's sarcoma. Kinsey M; Smith R; Iyer AK; McCabe ER; Lessnick SL Cancer Res; 2009 Dec; 69(23):9047-55. PubMed ID: 19920188 [TBL] [Abstract][Full Text] [Related]
3. Expression profiling of EWS/FLI identifies NKX2.2 as a critical target gene in Ewing's sarcoma. Smith R; Owen LA; Trem DJ; Wong JS; Whangbo JS; Golub TR; Lessnick SL Cancer Cell; 2006 May; 9(5):405-16. PubMed ID: 16697960 [TBL] [Abstract][Full Text] [Related]
4. NR0B1 is required for the oncogenic phenotype mediated by EWS/FLI in Ewing's sarcoma. Kinsey M; Smith R; Lessnick SL Mol Cancer Res; 2006 Nov; 4(11):851-9. PubMed ID: 17114343 [TBL] [Abstract][Full Text] [Related]
5. GSTM4 is a microsatellite-containing EWS/FLI target involved in Ewing's sarcoma oncogenesis and therapeutic resistance. Luo W; Gangwal K; Sankar S; Boucher KM; Thomas D; Lessnick SL Oncogene; 2009 Nov; 28(46):4126-32. PubMed ID: 19718047 [TBL] [Abstract][Full Text] [Related]
6. Caveolin-1 (CAV1) is a target of EWS/FLI-1 and a key determinant of the oncogenic phenotype and tumorigenicity of Ewing's sarcoma cells. Tirado OM; Mateo-Lozano S; Villar J; Dettin LE; Llort A; Gallego S; Ban J; Kovar H; Notario V Cancer Res; 2006 Oct; 66(20):9937-47. PubMed ID: 17047056 [TBL] [Abstract][Full Text] [Related]
7. Identification of target genes in their native cellular context: an analysis of EWS/FLI in Ewing's sarcoma. Owen LA; Lessnick SL Cell Cycle; 2006 Sep; 5(18):2049-53. PubMed ID: 16969112 [TBL] [Abstract][Full Text] [Related]
8. BCL11B is up-regulated by EWS/FLI and contributes to the transformed phenotype in Ewing sarcoma. Wiles ET; Lui-Sargent B; Bell R; Lessnick SL PLoS One; 2013; 8(3):e59369. PubMed ID: 23527175 [TBL] [Abstract][Full Text] [Related]
10. Mechanism and relevance of EWS/FLI-mediated transcriptional repression in Ewing sarcoma. Sankar S; Bell R; Stephens B; Zhuo R; Sharma S; Bearss DJ; Lessnick SL Oncogene; 2013 Oct; 32(42):5089-100. PubMed ID: 23178492 [TBL] [Abstract][Full Text] [Related]
11. Transformation induced by Ewing's sarcoma associated EWS/FLI-1 is suppressed by KRAB/FLI-1. Chan D; Wilson TJ; Xu D; Cowdery HE; Sanij E; Hertzog PJ; Kola I Br J Cancer; 2003 Jan; 88(1):137-45. PubMed ID: 12556973 [TBL] [Abstract][Full Text] [Related]
12. Alteration of mesodermal cell differentiation by EWS/FLI-1, the oncogene implicated in Ewing's sarcoma. Eliazer S; Spencer J; Ye D; Olson E; Ilaria RL Mol Cell Biol; 2003 Jan; 23(2):482-92. PubMed ID: 12509448 [TBL] [Abstract][Full Text] [Related]
13. Small-molecule screen identifies modulators of EWS/FLI1 target gene expression and cell survival in Ewing's sarcoma. Boro A; PrĂȘtre K; Rechfeld F; Thalhammer V; Oesch S; Wachtel M; SchĂ€fer BW; Niggli FK Int J Cancer; 2012 Nov; 131(9):2153-64. PubMed ID: 22323082 [TBL] [Abstract][Full Text] [Related]
14. Ewing's sarcoma: general insights from a rare model. Davis S; Meltzer PS Cancer Cell; 2006 May; 9(5):331-2. PubMed ID: 16697953 [TBL] [Abstract][Full Text] [Related]
15. Microsatellites as EWS/FLI response elements in Ewing's sarcoma. Gangwal K; Sankar S; Hollenhorst PC; Kinsey M; Haroldsen SC; Shah AA; Boucher KM; Watkins WS; Jorde LB; Graves BJ; Lessnick SL Proc Natl Acad Sci U S A; 2008 Jul; 105(29):10149-54. PubMed ID: 18626011 [TBL] [Abstract][Full Text] [Related]
16. Junction region of EWS-FLI1 fusion protein has a dominant negative effect in Ewing's sarcoma in vitro. Jully B; Vijayalakshmi R; Gopal G; Sabitha K; Rajkumar T BMC Cancer; 2012 Nov; 12():513. PubMed ID: 23145994 [TBL] [Abstract][Full Text] [Related]
17. EWS/FLI-1 silencing and gene profiling of Ewing cells reveal downstream oncogenic pathways and a crucial role for repression of insulin-like growth factor binding protein 3. Prieur A; Tirode F; Cohen P; Delattre O Mol Cell Biol; 2004 Aug; 24(16):7275-83. PubMed ID: 15282325 [TBL] [Abstract][Full Text] [Related]
18. Interference with the constitutive activation of ERK1 and ERK2 impairs EWS/FLI-1-dependent transformation. Silvany RE; Eliazer S; Wolff NC; Ilaria RL Oncogene; 2000 Sep; 19(39):4523-30. PubMed ID: 11002425 [TBL] [Abstract][Full Text] [Related]
19. Targeting of EWS/FLI-1 by RNA interference attenuates the tumor phenotype of Ewing's sarcoma cells in vitro. Chansky HA; Barahmand-Pour F; Mei Q; Kahn-Farooqi W; Zielinska-Kwiatkowska A; Blackburn M; Chansky K; Conrad EU; Bruckner JD; Greenlee TK; Yang L J Orthop Res; 2004 Jul; 22(4):910-7. PubMed ID: 15183454 [TBL] [Abstract][Full Text] [Related]
20. The Ewing's sarcoma oncoprotein EWS/FLI induces a p53-dependent growth arrest in primary human fibroblasts. Lessnick SL; Dacwag CS; Golub TR Cancer Cell; 2002 May; 1(4):393-401. PubMed ID: 12086853 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]