BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

336 related articles for article (PubMed ID: 18414682)

  • 1. Diminished Ret expression compromises neuronal survival in the colon and causes intestinal aganglionosis in mice.
    Uesaka T; Nagashimada M; Yonemura S; Enomoto H
    J Clin Invest; 2008 May; 118(5):1890-8. PubMed ID: 18414682
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Glial Cell-Derived Neurotrophic Factor Induces Enteric Neurogenesis and Improves Colon Structure and Function in Mouse Models of Hirschsprung Disease.
    Soret R; Schneider S; Bernas G; Christophers B; Souchkova O; Charrier B; Righini-Grunder F; Aspirot A; Landry M; Kembel SW; Faure C; Heuckeroth RO; Pilon N
    Gastroenterology; 2020 Nov; 159(5):1824-1838.e17. PubMed ID: 32687927
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Neural precursor death is central to the pathogenesis of intestinal aganglionosis in Ret hypomorphic mice.
    Uesaka T; Enomoto H
    J Neurosci; 2010 Apr; 30(15):5211-8. PubMed ID: 20392943
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Expression of PROKR1 and PROKR2 in human enteric neural precursor cells and identification of sequence variants suggest a role in HSCR.
    Ruiz-Ferrer M; Torroglosa A; Núñez-Torres R; de Agustín JC; Antiñolo G; Borrego S
    PLoS One; 2011; 6(8):e23475. PubMed ID: 21858136
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A Novel Zebrafish ret Heterozygous Model of Hirschsprung Disease Identifies a Functional Role for mapk10 as a Modifier of Enteric Nervous System Phenotype Severity.
    Heanue TA; Boesmans W; Bell DM; Kawakami K; Vanden Berghe P; Pachnis V
    PLoS Genet; 2016 Nov; 12(11):e1006439. PubMed ID: 27902697
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Germline mutations of the RET ligand GDNF are not sufficient to cause Hirschsprung disease.
    Salomon R; Attié T; Pelet A; Bidaud C; Eng C; Amiel J; Sarnacki S; Goulet O; Ricour C; Nihoul-Fékété C; Munnich A; Lyonnet S
    Nat Genet; 1996 Nov; 14(3):345-7. PubMed ID: 8896569
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Germline mutations in glial cell line-derived neurotrophic factor (GDNF) and RET in a Hirschsprung disease patient.
    Angrist M; Bolk S; Halushka M; Lapchak PA; Chakravarti A
    Nat Genet; 1996 Nov; 14(3):341-4. PubMed ID: 8896568
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Correction of Hirschsprung-Associated Mutations in Human Induced Pluripotent Stem Cells Via Clustered Regularly Interspaced Short Palindromic Repeats/Cas9, Restores Neural Crest Cell Function.
    Lai FP; Lau ST; Wong JK; Gui H; Wang RX; Zhou T; Lai WH; Tse HF; Tam PK; Garcia-Barcelo MM; Ngan ES
    Gastroenterology; 2017 Jul; 153(1):139-153.e8. PubMed ID: 28342760
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Conditional ablation of GFRalpha1 in postmigratory enteric neurons triggers unconventional neuronal death in the colon and causes a Hirschsprung's disease phenotype.
    Uesaka T; Jain S; Yonemura S; Uchiyama Y; Milbrandt J; Enomoto H
    Development; 2007 Jun; 134(11):2171-81. PubMed ID: 17507417
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Gfra1 Underexpression Causes Hirschsprung's Disease and Associated Enterocolitis in Mice.
    Porokuokka LL; Virtanen HT; Lindén J; Sidorova Y; Danilova T; Lindahl M; Saarma M; Andressoo JO
    Cell Mol Gastroenterol Hepatol; 2019; 7(3):655-678. PubMed ID: 30594740
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A Single RET Mutation in Hirschsprung Disease Induces Intestinal Aganglionosis Via a Dominant-Negative Mechanism.
    Sunardi M; Ito K; Sato Y; Uesaka T; Iwasaki M; Enomoto H
    Cell Mol Gastroenterol Hepatol; 2023; 15(6):1505-1524. PubMed ID: 36521661
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Regulators of gene expression in Enteric Neural Crest Cells are putative Hirschsprung disease genes.
    Schriemer D; Sribudiani Y; IJpma A; Natarajan D; MacKenzie KC; Metzger M; Binder E; Burns AJ; Thapar N; Hofstra RMW; Eggen BJL
    Dev Biol; 2016 Aug; 416(1):255-265. PubMed ID: 27266404
    [TBL] [Abstract][Full Text] [Related]  

  • 13. L1cam acts as a modifier gene during enteric nervous system development.
    Wallace AS; Schmidt C; Schachner M; Wegner M; Anderson RB
    Neurobiol Dis; 2010 Dec; 40(3):622-33. PubMed ID: 20696247
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Identification of Variants in RET and IHH Pathway Members in a Large Family With History of Hirschsprung Disease.
    Sribudiani Y; Chauhan RK; Alves MM; Petrova L; Brosens E; Harrison C; Wabbersen T; de Graaf BM; Rügenbrink T; Burzynski G; Brouwer RWW; van IJcken WFJ; Maas SM; de Klein A; Osinga J; Eggen BJL; Burns AJ; Brooks AS; Shepherd IT; Hofstra RMW
    Gastroenterology; 2018 Jul; 155(1):118-129.e6. PubMed ID: 29601828
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mutational analysis of RET/GDNF/NTN genes in children with total colonic aganglionosis with small bowel involvement.
    Inoue K; Shimotake T; Iwai N
    Am J Med Genet; 2000 Aug; 93(4):278-84. PubMed ID: 10946353
    [TBL] [Abstract][Full Text] [Related]  

  • 16. RET overactivation leads to concurrent Hirschsprung disease and intestinal ganglioneuromas.
    Nagy N; Guyer RA; Hotta R; Zhang D; Newgreen DF; Halasy V; Kovacs T; Goldstein AM
    Development; 2020 Nov; 147(21):. PubMed ID: 32994173
    [TBL] [Abstract][Full Text] [Related]  

  • 17. RET and NRG1 interplay in Hirschsprung disease.
    Gui H; Tang WK; So MT; Proitsi P; Sham PC; Tam PK; Ngan ES; Cherny SS; Garcia-Barceló MM
    Hum Genet; 2013 May; 132(5):591-600. PubMed ID: 23400839
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Neuronal Differentiation in Schwann Cell Lineage Underlies Postnatal Neurogenesis in the Enteric Nervous System.
    Uesaka T; Nagashimada M; Enomoto H
    J Neurosci; 2015 Jul; 35(27):9879-88. PubMed ID: 26156989
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The GDNF System Is Altered in Diverticular Disease - Implications for Pathogenesis.
    Böttner M; Barrenschee M; Hellwig I; Harde J; Egberts JH; Becker T; Zorenkov D; Schäfer KH; Wedel T
    PLoS One; 2013; 8(6):e66290. PubMed ID: 23805210
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Glial cell line-derived neurotrophic factor family receptors are abnormally expressed in aganglionic bowel of a subpopulation of patients with Hirschsprung's disease.
    Lui VC; Samy ET; Sham MH; Mulligan LM; Tam PK
    Lab Invest; 2002 Jun; 82(6):703-12. PubMed ID: 12065680
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.