BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

448 related articles for article (PubMed ID: 18419600)

  • 21. The p53-p21WAF1 checkpoint pathway plays a protective role in preventing DNA rereplication induced by abrogation of FOXF1 function.
    Lo PK; Lee JS; Sukumar S
    Cell Signal; 2012 Jan; 24(1):316-24. PubMed ID: 21964066
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Sp3, but not Sp1, mediates the transcriptional activation of the p21/WAF1/Cip1 gene promoter by histone deacetylase inhibitor.
    Sowa Y; Orita T; Minamikawa-Hiranabe S; Mizuno T; Nomura H; Sakai T
    Cancer Res; 1999 Sep; 59(17):4266-70. PubMed ID: 10485470
    [TBL] [Abstract][Full Text] [Related]  

  • 23. The histone deacetylase inhibitor trichostatin a decreases lymphangiogenesis by inducing apoptosis and cell cycle arrest via p21-dependent pathways.
    Hrgovic I; Doll M; Kleemann J; Wang XF; Zoeller N; Pinter A; Kippenberger S; Kaufmann R; Meissner M
    BMC Cancer; 2016 Sep; 16(1):763. PubMed ID: 27716272
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Investigation of the role of Bax, p21/Waf1 and p53 as determinants of cellular responses in HCT116 colorectal cancer cells exposed to the novel cytotoxic ruthenium(II) organometallic agent, RM175.
    Hayward RL; Schornagel QC; Tente R; Macpherson JS; Aird RE; Guichard S; Habtemariam A; Sadler P; Jodrell DI
    Cancer Chemother Pharmacol; 2005 Jun; 55(6):577-83. PubMed ID: 15726367
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Histone deacetylase inhibitor selectively induces p21WAF1 expression and gene-associated histone acetylation.
    Richon VM; Sandhoff TW; Rifkind RA; Marks PA
    Proc Natl Acad Sci U S A; 2000 Aug; 97(18):10014-9. PubMed ID: 10954755
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Increased expression of integrin beta1 subunit enhances p21WAF1/Cip1 transcription through the Sp1 sites and p300-mediated histone acetylation in human hepatocellular carcinoma cells.
    Fang Z; Fu Y; Liang Y; Li Z; Zhang W; Jin J; Yang Y; Zha X
    J Cell Biochem; 2007 Jun; 101(3):654-64. PubMed ID: 17211849
    [TBL] [Abstract][Full Text] [Related]  

  • 27. ING1 represses transcription by direct DNA binding and through effects on p53.
    Kataoka H; Bonnefin P; Vieyra D; Feng X; Hara Y; Miura Y; Joh T; Nakabayashi H; Vaziri H; Harris CC; Riabowol K
    Cancer Res; 2003 Sep; 63(18):5785-92. PubMed ID: 14522900
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Histone deacetylase inhibitor induces cell apoptosis and cycle arrest in lung cancer cells via mitochondrial injury and p53 up-acetylation.
    Bao L; Diao H; Dong N; Su X; Wang B; Mo Q; Yu H; Wang X; Chen C
    Cell Biol Toxicol; 2016 Dec; 32(6):469-482. PubMed ID: 27423454
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Sp1 plays a critical role in the transcriptional activation of the human cyclin-dependent kinase inhibitor p21(WAF1/Cip1) gene by the p53 tumor suppressor protein.
    Koutsodontis G; Tentes I; Papakosta P; Moustakas A; Kardassis D
    J Biol Chem; 2001 Aug; 276(31):29116-25. PubMed ID: 11384995
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Histone deacetylase inhibitor, Trichostatin A, activates p21WAF1/CIP1 expression through downregulation of c-myc and release of the repression of c-myc from the promoter in human cervical cancer cells.
    Li H; Wu X
    Biochem Biophys Res Commun; 2004 Nov; 324(2):860-7. PubMed ID: 15474507
    [TBL] [Abstract][Full Text] [Related]  

  • 31. An ATM- and Rad3-related (ATR) signaling pathway and a phosphorylation-acetylation cascade are involved in activation of p53/p21Waf1/Cip1 in response to 5-aza-2'-deoxycytidine treatment.
    Wang H; Zhao Y; Li L; McNutt MA; Wu L; Lu S; Yu Y; Zhou W; Feng J; Chai G; Yang Y; Zhu WG
    J Biol Chem; 2008 Feb; 283(5):2564-74. PubMed ID: 17977830
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Deacetylase inhibition in malignant melanomas: impact on cell cycle regulation and survival.
    Flørenes VA; Skrede M; Jørgensen K; Nesland JM
    Melanoma Res; 2004 Jun; 14(3):173-81. PubMed ID: 15179185
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Loss of p53 has site-specific effects on histone H3 modification, including serine 10 phosphorylation important for maintenance of ploidy.
    Allison SJ; Milner J
    Cancer Res; 2003 Oct; 63(20):6674-9. PubMed ID: 14583461
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Site-specific acetylation of p53 directs selective transcription complex assembly.
    Roy S; Tenniswood M
    J Biol Chem; 2007 Feb; 282(7):4765-4771. PubMed ID: 17121856
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Induction of PIG3 and NOXA through acetylation of p53 at 320 and 373 lysine residues as a mechanism for apoptotic cell death by histone deacetylase inhibitors.
    Terui T; Murakami K; Takimoto R; Takahashi M; Takada K; Murakami T; Minami S; Matsunaga T; Takayama T; Kato J; Niitsu Y
    Cancer Res; 2003 Dec; 63(24):8948-54. PubMed ID: 14695212
    [TBL] [Abstract][Full Text] [Related]  

  • 36. LKB1 is recruited to the p21/WAF1 promoter by p53 to mediate transcriptional activation.
    Zeng PY; Berger SL
    Cancer Res; 2006 Nov; 66(22):10701-8. PubMed ID: 17108107
    [TBL] [Abstract][Full Text] [Related]  

  • 37. p53-Dependent transcriptional repression of c-myc is required for G1 cell cycle arrest.
    Ho JS; Ma W; Mao DY; Benchimol S
    Mol Cell Biol; 2005 Sep; 25(17):7423-31. PubMed ID: 16107691
    [TBL] [Abstract][Full Text] [Related]  

  • 38. The histone acetyltransferase PCAF regulates p21 transcription through stress-induced acetylation of histone H3.
    Love IM; Sekaric P; Shi D; Grossman SR; Androphy EJ
    Cell Cycle; 2012 Jul; 11(13):2458-66. PubMed ID: 22713239
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Indirect p53-dependent transcriptional repression of Survivin, CDC25C, and PLK1 genes requires the cyclin-dependent kinase inhibitor p21/CDKN1A and CDE/CHR promoter sites binding the DREAM complex.
    Fischer M; Quaas M; Nickel A; Engeland K
    Oncotarget; 2015 Dec; 6(39):41402-17. PubMed ID: 26595675
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Histone deacetylase inhibitors all induce p21 but differentially cause tubulin acetylation, mitotic arrest, and cytotoxicity.
    Blagosklonny MV; Robey R; Sackett DL; Du L; Traganos F; Darzynkiewicz Z; Fojo T; Bates SE
    Mol Cancer Ther; 2002 Sep; 1(11):937-41. PubMed ID: 12481415
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 23.