BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

292 related articles for article (PubMed ID: 18421014)

  • 1. Curcumin restores corticosteroid function in monocytes exposed to oxidants by maintaining HDAC2.
    Meja KK; Rajendrasozhan S; Adenuga D; Biswas SK; Sundar IK; Spooner G; Marwick JA; Chakravarty P; Fletcher D; Whittaker P; Megson IL; Kirkham PA; Rahman I
    Am J Respir Cell Mol Biol; 2008 Sep; 39(3):312-23. PubMed ID: 18421014
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Histone deacetylase 2 is phosphorylated, ubiquitinated, and degraded by cigarette smoke.
    Adenuga D; Yao H; March TH; Seagrave J; Rahman I
    Am J Respir Cell Mol Biol; 2009 Apr; 40(4):464-73. PubMed ID: 18927347
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Curcumin modulates the effect of histone modification on the expression of chemokines by type II alveolar epithelial cells in a rat COPD model.
    Gan L; Li C; Wang J; Guo X
    Int J Chron Obstruct Pulmon Dis; 2016; 11():2765-2773. PubMed ID: 27853364
    [TBL] [Abstract][Full Text] [Related]  

  • 4. [Erythromycin restores oxidative stress-induced corticosteroid responsiveness of human THP-1 cells by up-regulating the expression of histone deacetylase 2].
    Zhang Y; He Z; Sun X; Li Z; Zhao L; Mao C; Huang D; Zhang J; Zhong X
    Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi; 2014 Apr; 30(4):384-7. PubMed ID: 24721407
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Role of HDAC2 in the pathophysiology of COPD.
    Barnes PJ
    Annu Rev Physiol; 2009; 71():451-64. PubMed ID: 18817512
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Nortriptyline reverses corticosteroid insensitivity by inhibition of phosphoinositide-3-kinase-δ.
    Mercado N; To Y; Ito K; Barnes PJ
    J Pharmacol Exp Ther; 2011 May; 337(2):465-70. PubMed ID: 21300705
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Combination of erythromycin and dexamethasone improves corticosteroid sensitivity induced by CSE through inhibiting PI3K-δ/Akt pathway and increasing GR expression.
    Sun XJ; Li ZH; Zhang Y; Zhou G; Zhang JQ; Deng JM; Bai J; Liu GN; Li MH; MacNee W; Zhong XN; He ZY
    Am J Physiol Lung Cell Mol Physiol; 2015 Jul; 309(2):L139-46. PubMed ID: 25957293
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Cryptotanshinone Reverses Corticosteroid Insensitivity by Inhibition of Phosphoinositide-3-Kinase-δ in Chronic Obstructive Pulmonary Disease.
    Xie T; Huang R; Deng D; Tang P; Fu Y; Zheng Y; Wan Y
    Int J Chron Obstruct Pulmon Dis; 2023; 18():797-809. PubMed ID: 37180749
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Restoration of HDAC2 and Nrf2 by andrographolide overcomes corticosteroid resistance in chronic obstructive pulmonary disease.
    Liao W; Lim AYH; Tan WSD; Abisheganaden J; Wong WSF
    Br J Pharmacol; 2020 Aug; 177(16):3662-3673. PubMed ID: 32335896
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Current perspectives on role of chromatin modifications and deacetylases in lung inflammation in COPD.
    Rajendrasozhan S; Yao H; Rahman I
    COPD; 2009 Aug; 6(4):291-7. PubMed ID: 19811389
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Corticosteroids: the drugs to beat.
    Barnes PJ
    Eur J Pharmacol; 2006 Mar; 533(1-3):2-14. PubMed ID: 16436275
    [TBL] [Abstract][Full Text] [Related]  

  • 12. USP17-mediated deubiquitination and stabilization of HDAC2 in cigarette smoke extract-induced inflammation.
    Song H; Tao L; Chen C; Pan L; Hao J; Ni Y; Li D; Li B; Shi G
    Int J Clin Exp Pathol; 2015; 8(9):10707-15. PubMed ID: 26617781
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A novel macrolide/fluoroketolide, solithromycin (CEM-101), reverses corticosteroid insensitivity via phosphoinositide 3-kinase pathway inhibition.
    Kobayashi Y; Wada H; Rossios C; Takagi D; Charron C; Barnes PJ; Ito K
    Br J Pharmacol; 2013 Jul; 169(5):1024-34. PubMed ID: 23758162
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Restoration of Corticosteroid Sensitivity in Chronic Obstructive Pulmonary Disease by Inhibition of Mammalian Target of Rapamycin.
    Mitani A; Ito K; Vuppusetty C; Barnes PJ; Mercado N
    Am J Respir Crit Care Med; 2016 Jan; 193(2):143-53. PubMed ID: 26426522
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Corticosteroid resistance in chronic obstructive pulmonary disease: inactivation of histone deacetylase.
    Barnes PJ; Ito K; Adcock IM
    Lancet; 2004 Feb; 363(9410):731-3. PubMed ID: 15001333
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Histone deacetylation: an important mechanism in inflammatory lung diseases.
    Adcock IM; Ito K; Barnes PJ
    COPD; 2005 Dec; 2(4):445-55. PubMed ID: 17147010
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Oxidative stress and steroid resistance in asthma and COPD: pharmacological manipulation of HDAC-2 as a therapeutic strategy.
    Marwick JA; Ito K; Adcock IM; Kirkham PA
    Expert Opin Ther Targets; 2007 Jun; 11(6):745-55. PubMed ID: 17504013
    [TBL] [Abstract][Full Text] [Related]  

  • 18. MicroRNA-223 controls the expression of histone deacetylase 2: a novel axis in COPD.
    Leuenberger C; Schuoler C; Bye H; Mignan C; Rechsteiner T; Hillinger S; Opitz I; Marsland B; Faiz A; Hiemstra PS; Timens W; Camici GG; Kohler M; Huber LC; Brock M
    J Mol Med (Berl); 2016 Jun; 94(6):725-34. PubMed ID: 26864305
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Theophylline and dexamethasone in combination reduce inflammation and prevent the decrease in HDAC2 expression seen in monocytes exposed to cigarette smoke extract.
    Sun XJ; Li ZH; Zhang Y; Zhong XN; He ZY; Zhou JH; Chen SN; Feng Y
    Exp Ther Med; 2020 May; 19(5):3425-3431. PubMed ID: 32269608
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Cigarette smoke induces proinflammatory cytokine release by activation of NF-kappaB and posttranslational modifications of histone deacetylase in macrophages.
    Yang SR; Chida AS; Bauter MR; Shafiq N; Seweryniak K; Maggirwar SB; Kilty I; Rahman I
    Am J Physiol Lung Cell Mol Physiol; 2006 Jul; 291(1):L46-57. PubMed ID: 16473865
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.