305 related articles for article (PubMed ID: 18423498)
1. Assessment of DNA double-strand breaks and gammaH2AX induced by the topoisomerase II poisons etoposide and mitoxantrone.
Smart DJ; Halicka HD; Schmuck G; Traganos F; Darzynkiewicz Z; Williams GM
Mutat Res; 2008 May; 641(1-2):43-7. PubMed ID: 18423498
[TBL] [Abstract][Full Text] [Related]
2. Assessment of histone H2AX phosphorylation induced by DNA topoisomerase I and II inhibitors topotecan and mitoxantrone and by the DNA cross-linking agent cisplatin.
Huang X; Okafuji M; Traganos F; Luther E; Holden E; Darzynkiewicz Z
Cytometry A; 2004 Apr; 58(2):99-110. PubMed ID: 15057963
[TBL] [Abstract][Full Text] [Related]
3. Induction of ATM activation, histone H2AX phosphorylation and apoptosis by etoposide: relation to cell cycle phase.
Tanaka T; Halicka HD; Traganos F; Seiter K; Darzynkiewicz Z
Cell Cycle; 2007 Feb; 6(3):371-6. PubMed ID: 17297310
[TBL] [Abstract][Full Text] [Related]
4. Relationship of DNA damage signaling to DNA replication following treatment with DNA topoisomerase inhibitors camptothecin/topotecan, mitoxantrone, or etoposide.
Zhao H; Rybak P; Dobrucki J; Traganos F; Darzynkiewicz Z
Cytometry A; 2012 Jan; 81(1):45-51. PubMed ID: 22140093
[TBL] [Abstract][Full Text] [Related]
5. Assessment of ATM phosphorylation on Ser-1981 induced by DNA topoisomerase I and II inhibitors in relation to Ser-139-histone H2AX phosphorylation, cell cycle phase, and apoptosis.
Kurose A; Tanaka T; Huang X; Halicka HD; Traganos F; Dai W; Darzynkiewicz Z
Cytometry A; 2005 Nov; 68(1):1-9. PubMed ID: 16184611
[TBL] [Abstract][Full Text] [Related]
6. Numerical analysis of etoposide induced DNA breaks.
Muslimović A; Nyström S; Gao Y; Hammarsten O
PLoS One; 2009 Jun; 4(6):e5859. PubMed ID: 19516899
[TBL] [Abstract][Full Text] [Related]
7. Cytometric assessment of DNA damage induced by DNA topoisomerase inhibitors.
Darzynkiewicz Z; Halicka DH; Tanaka T
Methods Mol Biol; 2009; 582():145-53. PubMed ID: 19763948
[TBL] [Abstract][Full Text] [Related]
8. Emodin triggers DNA double-strand breaks by stabilizing topoisomerase II-DNA cleavage complexes and by inhibiting ATP hydrolysis of topoisomerase II.
Li Y; Luan Y; Qi X; Li M; Gong L; Xue X; Wu X; Wu Y; Chen M; Xing G; Yao J; Ren J
Toxicol Sci; 2010 Dec; 118(2):435-43. PubMed ID: 20855424
[TBL] [Abstract][Full Text] [Related]
9. Rac1 protein signaling is required for DNA damage response stimulated by topoisomerase II poisons.
Huelsenbeck SC; Schorr A; Roos WP; Huelsenbeck J; Henninger C; Kaina B; Fritz G
J Biol Chem; 2012 Nov; 287(46):38590-9. PubMed ID: 23012366
[TBL] [Abstract][Full Text] [Related]
10. WRN protects against topo I but not topo II inhibitors by preventing DNA break formation.
Christmann M; Tomicic MT; Gestrich C; Roos WP; Bohr VA; Kaina B
DNA Repair (Amst); 2008 Dec; 7(12):1999-2009. PubMed ID: 18805512
[TBL] [Abstract][Full Text] [Related]
11. Ciprofloxacin-induced G2 arrest and apoptosis in TK6 lymphoblastoid cells is not dependent on DNA double-strand break formation.
Smart DJ; Halicka HD; Traganos F; Darzynkiewicz Z; Williams GM
Cancer Biol Ther; 2008 Jan; 7(1):113-9. PubMed ID: 18059176
[TBL] [Abstract][Full Text] [Related]
12. Kinetics of histone H2AX phosphorylation and Chk2 activation in A549 cells treated with topotecan and mitoxantrone in relation to the cell cycle phase.
Zhao H; Traganos F; Darzynkiewicz Z
Cytometry A; 2008 Jun; 73(6):480-9. PubMed ID: 18459160
[TBL] [Abstract][Full Text] [Related]
13. Low level phosphorylation of histone H2AX on serine 139 (γH2AX) is not associated with DNA double-strand breaks.
Rybak P; Hoang A; Bujnowicz L; Bernas T; Berniak K; Zarębski M; Darzynkiewicz Z; Dobrucki J
Oncotarget; 2016 Aug; 7(31):49574-49587. PubMed ID: 27391338
[TBL] [Abstract][Full Text] [Related]
14. Loss of histone H2AX increases sensitivity of immortalized mouse fibroblasts to the topoisomerase II inhibitor etoposide.
Donà F; Prosperi E; Savio M; Coppa T; Scovassi AI; Mondello C
Int J Oncol; 2008 Sep; 33(3):613-21. PubMed ID: 18695893
[TBL] [Abstract][Full Text] [Related]
15. Topotecan-induced topoisomerase IIalpha expression increases the sensitivity of the CML cell line K562 to subsequent etoposide plus mitoxantrone treatment.
Chen S; Gomez SP; McCarley D; Mainwaring MG
Cancer Chemother Pharmacol; 2002 May; 49(5):347-55. PubMed ID: 11976828
[TBL] [Abstract][Full Text] [Related]
16. Tirapazamine: a hypoxia-activated topoisomerase II poison.
Peters KB; Brown JM
Cancer Res; 2002 Sep; 62(18):5248-53. PubMed ID: 12234992
[TBL] [Abstract][Full Text] [Related]
17. Reduction in drug-induced DNA double-strand breaks associated with beta1 integrin-mediated adhesion correlates with drug resistance in U937 cells.
Hazlehurst LA; Valkov N; Wisner L; Storey JA; Boulware D; Sullivan DM; Dalton WS
Blood; 2001 Sep; 98(6):1897-903. PubMed ID: 11535527
[TBL] [Abstract][Full Text] [Related]
18. The γH2AX assay for genotoxic and nongenotoxic agents: comparison of H2AX phosphorylation with cell death response.
Nikolova T; Dvorak M; Jung F; Adam I; Krämer E; Gerhold-Ay A; Kaina B
Toxicol Sci; 2014 Jul; 140(1):103-17. PubMed ID: 24743697
[TBL] [Abstract][Full Text] [Related]
19. The loss of gammaH2AX signal is a marker of DNA double strand breaks repair only at low levels of DNA damage.
Bouquet F; Muller C; Salles B
Cell Cycle; 2006 May; 5(10):1116-22. PubMed ID: 16721046
[TBL] [Abstract][Full Text] [Related]
20. Activation of ATM and histone H2AX phosphorylation induced by mitoxantrone but not by topotecan is prevented by the antioxidant N-acetyl-L-cysteine.
Huang X; Kurose A; Tanaka T; Traganos F; Dai W; Darzynkiewicz Z
Cancer Biol Ther; 2006 Aug; 5(8):959-64. PubMed ID: 16760673
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]