These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

211 related articles for article (PubMed ID: 18434593)

  • 21. Cellular inhibitor of apoptosis 1 and 2 are ubiquitin ligases for the apoptosis inducer Smac/DIABLO.
    Hu S; Yang X
    J Biol Chem; 2003 Mar; 278(12):10055-60. PubMed ID: 12525502
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Ubiquitin-protein ligase activity of X-linked inhibitor of apoptosis protein promotes proteasomal degradation of caspase-3 and enhances its anti-apoptotic effect in Fas-induced cell death.
    Suzuki Y; Nakabayashi Y; Takahashi R
    Proc Natl Acad Sci U S A; 2001 Jul; 98(15):8662-7. PubMed ID: 11447297
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Targeted Degradation of Proteins Localized in Subcellular Compartments by Hybrid Small Molecules.
    Okuhira K; Shoda T; Omura R; Ohoka N; Hattori T; Shibata N; Demizu Y; Sugihara R; Ichino A; Kawahara H; Itoh Y; Ishikawa M; Hashimoto Y; Kurihara M; Itoh S; Saito H; Naito M
    Mol Pharmacol; 2017 Mar; 91(3):159-166. PubMed ID: 27965304
    [TBL] [Abstract][Full Text] [Related]  

  • 24. IAPs contain an evolutionarily conserved ubiquitin-binding domain that regulates NF-kappaB as well as cell survival and oncogenesis.
    Gyrd-Hansen M; Darding M; Miasari M; Santoro MM; Zender L; Xue W; Tenev T; da Fonseca PC; Zvelebil M; Bujnicki JM; Lowe S; Silke J; Meier P
    Nat Cell Biol; 2008 Nov; 10(11):1309-17. PubMed ID: 18931663
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Inhibitor of apoptosis proteins as novel targets in inflammatory processes.
    Mayer BA; Rehberg M; Erhardt A; Wolf A; Reichel CA; Kracht M; Krombach F; Tiegs G; Zahler S; Vollmar AM; Fürst R
    Arterioscler Thromb Vasc Biol; 2011 Oct; 31(10):2240-50. PubMed ID: 21817100
    [TBL] [Abstract][Full Text] [Related]  

  • 26. The susceptibility to Fas-induced apoptosis in normal enterocytes is regulated on the level of cIAP1 and 2.
    Ruemmele FM; Beaulieu JF; O'Connell J; Bennett MW; Seidman EG; Lentze MJ
    Biochem Biophys Res Commun; 2002 Feb; 290(4):1308-14. PubMed ID: 11812006
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Inhibitor of apoptosis proteins are regulated by tumour necrosis factor-alpha in malignant pleural mesothelioma.
    Gordon GJ; Mani M; Mukhopadhyay L; Dong L; Yeap BY; Sugarbaker DJ; Bueno R
    J Pathol; 2007 Mar; 211(4):439-46. PubMed ID: 17253597
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Characterization of Potent SMAC Mimetics that Sensitize Cancer Cells to TNF Family-Induced Apoptosis.
    Welsh K; Milutinovic S; Ardecky RJ; Gonzalez-Lopez M; Ganji SR; Teriete P; Finlay D; Riedl S; Matsuzawa S; Pinilla C; Houghten R; Vuori K; Reed JC; Cosford ND
    PLoS One; 2016; 11(9):e0161952. PubMed ID: 27617834
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Modulation of immune signalling by inhibitors of apoptosis.
    Beug ST; Cheung HH; LaCasse EC; Korneluk RG
    Trends Immunol; 2012 Nov; 33(11):535-45. PubMed ID: 22836014
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Ubiquitin-proteasome dependent regulation of Profilin2 (Pfn2) by a cellular inhibitor of apoptotic protein 1 (cIAP1).
    Jeong DH; Choi YN; Seo TW; Lee JS; Yoo SJ
    Biochem Biophys Res Commun; 2018 Nov; 506(3):423-428. PubMed ID: 30352681
    [TBL] [Abstract][Full Text] [Related]  

  • 31. PDLIM7 Synergizes With PDLIM2 and p62/Sqstm1 to Inhibit Inflammatory Signaling by Promoting Degradation of the p65 Subunit of NF-κB.
    Jodo A; Shibazaki A; Onuma A; Kaisho T; Tanaka T
    Front Immunol; 2020; 11():1559. PubMed ID: 32849529
    [TBL] [Abstract][Full Text] [Related]  

  • 32. The E3 ubiquitin ligase SCF(Fbxo7) mediates proteasomal degradation of UXT isoform 2 (UXT-V2) to inhibit the NF-κB signaling pathway.
    Spagnol V; Oliveira CAB; Randle SJ; Passos PMS; Correia CRSTB; Simaroli NB; Oliveira JS; Mevissen TET; Medeiros AC; Gomes MD; Komander D; Laman H; Teixeira FR
    Biochim Biophys Acta Gen Subj; 2021 Jan; 1865(1):129754. PubMed ID: 33010352
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Double protein knockdown of cIAP1 and CRABP-II using a hybrid molecule consisting of ATRA and IAPs antagonist.
    Itoh Y; Ishikawa M; Kitaguchi R; Okuhira K; Naito M; Hashimoto Y
    Bioorg Med Chem Lett; 2012 Jul; 22(13):4453-7. PubMed ID: 22658364
    [TBL] [Abstract][Full Text] [Related]  

  • 34. cIAP1/2 are direct E3 ligases conjugating diverse types of ubiquitin chains to receptor interacting proteins kinases 1 to 4 (RIP1-4).
    Bertrand MJ; Lippens S; Staes A; Gilbert B; Roelandt R; De Medts J; Gevaert K; Declercq W; Vandenabeele P
    PLoS One; 2011; 6(9):e22356. PubMed ID: 21931591
    [TBL] [Abstract][Full Text] [Related]  

  • 35. TRIM32 protein sensitizes cells to tumor necrosis factor (TNFα)-induced apoptosis via its RING domain-dependent E3 ligase activity against X-linked inhibitor of apoptosis (XIAP).
    Ryu YS; Lee Y; Lee KW; Hwang CY; Maeng JS; Kim JH; Seo YS; You KH; Song B; Kwon KS
    J Biol Chem; 2011 Jul; 286(29):25729-38. PubMed ID: 21628460
    [TBL] [Abstract][Full Text] [Related]  

  • 36. CLL cells are resistant to smac mimetics because of an inability to form a ripoptosome complex.
    Maas C; Tromp JM; van Laar J; Thijssen R; Elias JA; Malara A; Krippner-Heidenreich A; Silke J; van Oers MH; Eldering E
    Cell Death Dis; 2013 Aug; 4(8):e782. PubMed ID: 23990022
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Suppression of autophagy during mitosis via CUL4-RING ubiquitin ligases-mediated WIPI2 polyubiquitination and proteasomal degradation.
    Lu G; Yi J; Gubas A; Wang YT; Wu Y; Ren Y; Wu M; Shi Y; Ouyang C; Tan HWS; Wang T; Wang L; Yang ND; Deng S; Xia D; Chen RH; Tooze SA; Shen HM
    Autophagy; 2019 Nov; 15(11):1917-1934. PubMed ID: 30898011
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Ubiquitin-associated domain-containing ubiquitin regulatory X (UBX) protein UBXN1 is a negative regulator of nuclear factor κB (NF-κB) signaling.
    Wang YB; Tan B; Mu R; Chang Y; Wu M; Tu HQ; Zhang YC; Guo SS; Qin XH; Li T; Li WH; Li AL; Zhang XM; Li HY
    J Biol Chem; 2015 Apr; 290(16):10395-405. PubMed ID: 25681446
    [TBL] [Abstract][Full Text] [Related]  

  • 39. cIAP1 and cIAP2 facilitate cancer cell survival by functioning as E3 ligases that promote RIP1 ubiquitination.
    Bertrand MJ; Milutinovic S; Dickson KM; Ho WC; Boudreault A; Durkin J; Gillard JW; Jaquith JB; Morris SJ; Barker PA
    Mol Cell; 2008 Jun; 30(6):689-700. PubMed ID: 18570872
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Triad3A regulates ubiquitination and proteasomal degradation of RIP1 following disruption of Hsp90 binding.
    Fearns C; Pan Q; Mathison JC; Chuang TH
    J Biol Chem; 2006 Nov; 281(45):34592-600. PubMed ID: 16968706
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 11.