BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

304 related articles for article (PubMed ID: 18436740)

  • 1. CXCR4 dimerization and beta-arrestin-mediated signaling account for the enhanced chemotaxis to CXCL12 in WHIM syndrome.
    Lagane B; Chow KY; Balabanian K; Levoye A; Harriague J; Planchenault T; Baleux F; Gunera-Saad N; Arenzana-Seisdedos F; Bachelerie F
    Blood; 2008 Jul; 112(1):34-44. PubMed ID: 18436740
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Leukocyte analysis from WHIM syndrome patients reveals a pivotal role for GRK3 in CXCR4 signaling.
    Balabanian K; Levoye A; Klemm L; Lagane B; Hermine O; Harriague J; Baleux F; Arenzana-Seisdedos F; Bachelerie F
    J Clin Invest; 2008 Mar; 118(3):1074-84. PubMed ID: 18274673
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Impaired recruitment of Grk6 and beta-Arrestin 2 causes delayed internalization and desensitization of a WHIM syndrome-associated CXCR4 mutant receptor.
    McCormick PJ; Segarra M; Gasperini P; Gulino AV; Tosato G
    PLoS One; 2009 Dec; 4(12):e8102. PubMed ID: 19956569
    [TBL] [Abstract][Full Text] [Related]  

  • 4. CXCL12/CXCR4-axis dysfunctions: Markers of the rare immunodeficiency disorder WHIM syndrome.
    Bachelerie F
    Dis Markers; 2010; 29(3-4):189-98. PubMed ID: 21178277
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Filamin A interaction with the CXCR4 third intracellular loop regulates endocytosis and signaling of WT and WHIM-like receptors.
    Gómez-Moutón C; Fischer T; Peregil RM; Jiménez-Baranda S; Stossel TP; Nakamura F; Mañes S
    Blood; 2015 Feb; 125(7):1116-25. PubMed ID: 25355818
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Genotype-phenotype correlations in WHIM syndrome: a systematic characterization of CXCR4
    Zmajkovicova K; Pawar S; Maier-Munsa S; Maierhofer B; Wiest I; Skerlj R; Taveras AG; Badarau A
    Genes Immun; 2022 Sep; 23(6):196-204. PubMed ID: 36089616
    [TBL] [Abstract][Full Text] [Related]  

  • 7. WHIM syndrome myelokathexis reproduced in the NOD/SCID mouse xenotransplant model engrafted with healthy human stem cells transduced with C-terminus-truncated CXCR4.
    Kawai T; Choi U; Cardwell L; DeRavin SS; Naumann N; Whiting-Theobald NL; Linton GF; Moon J; Murphy PM; Malech HL
    Blood; 2007 Jan; 109(1):78-84. PubMed ID: 16946301
    [TBL] [Abstract][Full Text] [Related]  

  • 8. WHIM syndromes with different genetic anomalies are accounted for by impaired CXCR4 desensitization to CXCL12.
    Balabanian K; Lagane B; Pablos JL; Laurent L; Planchenault T; Verola O; Lebbe C; Kerob D; Dupuy A; Hermine O; Nicolas JF; Latger-Cannard V; Bensoussan D; Bordigoni P; Baleux F; Le Deist F; Virelizier JL; Arenzana-Seisdedos F; Bachelerie F
    Blood; 2005 Mar; 105(6):2449-57. PubMed ID: 15536153
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Reduced G protein signaling despite impaired internalization and β-arrestin recruitment in patients carrying a CXCR4Leu317fsX3 mutation causing WHIM syndrome.
    Kumar R; Milanesi S; Szpakowska M; Dotta L; Di Silvestre D; Trotta AM; Bello AM; Giacomelli M; Benedito M; Azevedo J; Pereira A; Cortesao E; Vacchini A; Castagna A; Pinelli M; Moratto D; Bonecchi R; Locati M; Scala S; Chevigné A; Borroni EM; Badolato R
    JCI Insight; 2023 Mar; 8(5):. PubMed ID: 36883568
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Altered leukocyte response to CXCL12 in patients with warts hypogammaglobulinemia, infections, myelokathexis (WHIM) syndrome.
    Gulino AV; Moratto D; Sozzani S; Cavadini P; Otero K; Tassone L; Imberti L; Pirovano S; Notarangelo LD; Soresina R; Mazzolari E; Nelson DL; Notarangelo LD; Badolato R
    Blood; 2004 Jul; 104(2):444-52. PubMed ID: 15026312
    [TBL] [Abstract][Full Text] [Related]  

  • 11. CXCR4-Specific Nanobodies as Potential Therapeutics for WHIM syndrome.
    de Wit RH; Heukers R; Brink HJ; Arsova A; Maussang D; Cutolo P; Strubbe B; Vischer HF; Bachelerie F; Smit MJ
    J Pharmacol Exp Ther; 2017 Oct; 363(1):35-44. PubMed ID: 28768817
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Clinical and genetic features of Warts, Hypogammaglobulinemia, Infections and Myelokathexis (WHIM) syndrome.
    Dotta L; Tassone L; Badolato R
    Curr Mol Med; 2011 Jun; 11(4):317-25. PubMed ID: 21506920
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Characterization of a new WHIM syndrome mutant reveals mechanistic differences in regulation of the chemokine receptor CXCR4.
    Luo J; De Pascali F; Richmond GW; Khojah AM; Benovic JL
    J Biol Chem; 2022 Feb; 298(2):101551. PubMed ID: 34973340
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Stromal-derived factor-1 abolishes constitutive apoptosis of WHIM syndrome neutrophils harbouring a truncating CXCR4 mutation.
    Sanmun D; Garwicz D; Smith CI; Palmblad J; Fadeel B
    Br J Haematol; 2006 Sep; 134(6):640-4. PubMed ID: 16899028
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Enhanced function with decreased internalization of carboxy-terminus truncated CXCR4 responsible for WHIM syndrome.
    Kawai T; Choi U; Whiting-Theobald NL; Linton GF; Brenner S; Sechler JM; Murphy PM; Malech HL
    Exp Hematol; 2005 Apr; 33(4):460-8. PubMed ID: 15781337
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The negative charge of the 343 site is essential for maintaining physiological functions of CXCR4.
    Wang L; Xiong Q; Li P; Chen G; Tariq N; Wu C
    BMC Mol Cell Biol; 2021 Jan; 22(1):8. PubMed ID: 33485325
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Live imaging of neutrophil motility in a zebrafish model of WHIM syndrome.
    Walters KB; Green JM; Surfus JC; Yoo SK; Huttenlocher A
    Blood; 2010 Oct; 116(15):2803-11. PubMed ID: 20592249
    [TBL] [Abstract][Full Text] [Related]  

  • 18. [CXCR4, a therapeutic target in rare immunodeficiencies?].
    Bignon A; Biajoux V; Bouchet-Delbos L; Emilie D; Lortholary O; Balabanian K
    Med Sci (Paris); 2011 Apr; 27(4):391-7. PubMed ID: 21524404
    [TBL] [Abstract][Full Text] [Related]  

  • 19. CXCR4 mutations in WHIM syndrome: a misguided immune system?
    Diaz GA
    Immunol Rev; 2005 Feb; 203():235-43. PubMed ID: 15661033
    [TBL] [Abstract][Full Text] [Related]  

  • 20. WHIM syndrome: a defect in CXCR4 signaling.
    Diaz GA; Gulino AV
    Curr Allergy Asthma Rep; 2005 Sep; 5(5):350-5. PubMed ID: 16091205
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.