BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

609 related articles for article (PubMed ID: 18437052)

  • 1. Involvement of the chromatin-remodeling factor BRG1/SMARCA4 in human cancer.
    Medina PP; Sanchez-Cespedes M
    Epigenetics; 2008; 3(2):64-8. PubMed ID: 18437052
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Oncogenesis caused by loss of the SNF5 tumor suppressor is dependent on activity of BRG1, the ATPase of the SWI/SNF chromatin remodeling complex.
    Wang X; Sansam CG; Thom CS; Metzger D; Evans JA; Nguyen PT; Roberts CW
    Cancer Res; 2009 Oct; 69(20):8094-101. PubMed ID: 19789351
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Loss of the SWI/SNF-ATPase subunit members SMARCF1 (ARID1A), SMARCA2 (BRM), SMARCA4 (BRG1) and SMARCB1 (INI1) in oesophageal adenocarcinoma.
    Schallenberg S; Bork J; Essakly A; Alakus H; Buettner R; Hillmer AM; Bruns C; Schroeder W; Zander T; Loeser H; Gebauer F; Quaas A
    BMC Cancer; 2020 Jan; 20(1):12. PubMed ID: 31906887
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Residual complexes containing SMARCA2 (BRM) underlie the oncogenic drive of SMARCA4 (BRG1) mutation.
    Wilson BG; Helming KC; Wang X; Kim Y; Vazquez F; Jagani Z; Hahn WC; Roberts CW
    Mol Cell Biol; 2014 Mar; 34(6):1136-44. PubMed ID: 24421395
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The BRG1 ATPase of human SWI/SNF chromatin remodeling enzymes as a driver of cancer.
    Wu Q; Lian JB; Stein JL; Stein GS; Nickerson JA; Imbalzano AN
    Epigenomics; 2017 Jun; 9(6):919-931. PubMed ID: 28521512
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Dual loss of the SWI/SNF complex ATPases SMARCA4/BRG1 and SMARCA2/BRM is highly sensitive and specific for small cell carcinoma of the ovary, hypercalcaemic type.
    Karnezis AN; Wang Y; Ramos P; Hendricks WP; Oliva E; D'Angelo E; Prat J; Nucci MR; Nielsen TO; Chow C; Leung S; Kommoss F; Kommoss S; Silva A; Ronnett BM; Rabban JT; Bowtell DD; Weissman BE; Trent JM; Gilks CB; Huntsman DG
    J Pathol; 2016 Feb; 238(3):389-400. PubMed ID: 26356327
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The SWI/SNF Complex: A Frequently Mutated Chromatin Remodeling Complex in Cancer.
    Nguyen VT; Tessema M; Weissman BE
    Cancer Treat Res; 2023; 190():211-244. PubMed ID: 38113003
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A synthetic lethality-based strategy to treat cancers harboring a genetic deficiency in the chromatin remodeling factor BRG1.
    Oike T; Ogiwara H; Tominaga Y; Ito K; Ando O; Tsuta K; Mizukami T; Shimada Y; Isomura H; Komachi M; Furuta K; Watanabe S; Nakano T; Yokota J; Kohno T
    Cancer Res; 2013 Sep; 73(17):5508-18. PubMed ID: 23872584
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mechanism of BRG1 silencing in primary cancers.
    Marquez-Vilendrer SB; Thompson K; Lu L; Reisman D
    Oncotarget; 2016 Aug; 7(35):56153-56169. PubMed ID: 27486753
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Aberrant expression of SWI/SNF catalytic subunits BRG1/BRM is associated with tumor development and increased invasiveness in prostate cancers.
    Sun A; Tawfik O; Gayed B; Thrasher JB; Hoestje S; Li C; Li B
    Prostate; 2007 Feb; 67(2):203-13. PubMed ID: 17075831
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Characterization of mammary tumors from Brg1 heterozygous mice.
    Bultman SJ; Herschkowitz JI; Godfrey V; Gebuhr TC; Yaniv M; Perou CM; Magnuson T
    Oncogene; 2008 Jan; 27(4):460-8. PubMed ID: 17637742
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Exquisite Sensitivity to Dual BRG1/BRM ATPase Inhibitors Reveals Broad SWI/SNF Dependencies in Acute Myeloid Leukemia.
    Rago F; Rodrigues LU; Bonney M; Sprouffske K; Kurth E; Elliott G; Ambrose J; Aspesi P; Oborski J; Chen JT; McDonald ER; Mapa FA; Ruddy DA; Kauffmann A; Abrams T; Bhang HC; Jagani Z
    Mol Cancer Res; 2022 Mar; 20(3):361-372. PubMed ID: 34799403
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Loss of SWI/SNF Chromatin Remodeling Alters NRF2 Signaling in Non-Small Cell Lung Carcinoma.
    Song S; Nguyen V; Schrank T; Mulvaney K; Walter V; Wei D; Orvis T; Desai N; Zhang J; Hayes DN; Zheng Y; Major MB; Weissman BE
    Mol Cancer Res; 2020 Dec; 18(12):1777-1788. PubMed ID: 32855269
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Discovery of Orally Active Inhibitors of Brahma Homolog (BRM)/SMARCA2 ATPase Activity for the Treatment of Brahma Related Gene 1 (BRG1)/SMARCA4-Mutant Cancers.
    Papillon JPN; Nakajima K; Adair CD; Hempel J; Jouk AO; Karki RG; Mathieu S; Möbitz H; Ntaganda R; Smith T; Visser M; Hill SE; Hurtado FK; Chenail G; Bhang HC; Bric A; Xiang K; Bushold G; Gilbert T; Vattay A; Dooley J; Costa EA; Park I; Li A; Farley D; Lounkine E; Yue QK; Xie X; Zhu X; Kulathila R; King D; Hu T; Vulic K; Cantwell J; Luu C; Jagani Z
    J Med Chem; 2018 Nov; 61(22):10155-10172. PubMed ID: 30339381
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Co-regulation of transcription by BRG1 and BRM, two mutually exclusive SWI/SNF ATPase subunits.
    Raab JR; Runge JS; Spear CC; Magnuson T
    Epigenetics Chromatin; 2017 Dec; 10(1):62. PubMed ID: 29273066
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Frequent BRG1/SMARCA4-inactivating mutations in human lung cancer cell lines.
    Medina PP; Romero OA; Kohno T; Montuenga LM; Pio R; Yokota J; Sanchez-Cespedes M
    Hum Mutat; 2008 May; 29(5):617-22. PubMed ID: 18386774
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Cdx2 Regulates Gene Expression through Recruitment of Brg1-associated Switch-Sucrose Non-fermentable (SWI-SNF) Chromatin Remodeling Activity.
    Nguyen TT; Savory JGA; Brooke-Bisschop T; Ringuette R; Foley T; Hess BL; Mulatz KJ; Trinkle-Mulcahy L; Lohnes D
    J Biol Chem; 2017 Feb; 292(8):3389-3399. PubMed ID: 28082674
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Downregulation of SWI/SNF chromatin remodeling factor subunits modulates cisplatin cytotoxicity.
    Kothandapani A; Gopalakrishnan K; Kahali B; Reisman D; Patrick SM
    Exp Cell Res; 2012 Oct; 318(16):1973-86. PubMed ID: 22721696
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Structure of the BRK domain of the SWI/SNF chromatin remodeling complex subunit BRG1 reveals a potential role in protein-protein interactions.
    Allen MD; Bycroft M; Zinzalla G
    Protein Sci; 2020 Apr; 29(4):1047-1053. PubMed ID: 31909846
    [TBL] [Abstract][Full Text] [Related]  

  • 20. In silico screening of cancer-associated mutations in the HSA domain of BRG1 and its role in affecting the Arp-HSA sub-complex of SWI/SNF.
    S AS; Goutham R N A; Mohan S S
    Comput Biol Chem; 2018 Dec; 77():109-115. PubMed ID: 30286321
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 31.